The Effect of Different Surgical Instruments for Bone Regeneration under the Surgery of Bone Defect on Rat Calvaria

• 資料種別: 博士論文
• タイトル: The Effect of Different Surgical Instruments for Bone Regeneration under the Surgery of Bone Defect on Rat Calvaria
• 著者・編者: 古森, 喬
• 著者標目: 古森, 喬
• 並列タイトル等: ラットの頭蓋骨手術に用いる器具の違いが骨再生に及ぼす影響
• 授与機関名: 大阪歯科大学
• 授与年月日: 2022-06-22
• 報告番号: 乙第1641号
• 学位: 博士（歯学）
• 本文の言語コード: eng
• 件名標目: Bone regeneration; Surgical instruments; Calvaria; Ultrasonic knife; Trephine bur
• 対象利用者: 一般
• 一般注記: In this study, we compared the healing process of bone defects treated with a trephine bur with those treated with an ultrasonic knife using a critical-sized bone defect model on rat calvaria. Nine-millimeter critical-size bone defects were prepared using both instruments in the calvaria of adult Sprague-Dawley rats. One and four weeks after the osteotomy, weperformed a histomorphometric analysis to evaluate bone regeneration around the cutting surface. Quantitative micro-computed tomography analyses of the bone volume in both groups suggested that ultrasonic knife surgery resulted in superior bone formation compared to that in trephine bur surgery. Furthermore, at the cutting surface, the ultrasonic knife treatment retained the alkaline phosphatase activity and new bone formation, which was identified using calcein staining, even one week after surgery. Considering the speed and volume of bone regeneration, the ultrasonic knife is likely to be the preferred over the trephine bur to perform osteotomies in implant surgery.; 2022年度
• 一次資料へのリンクURL: fulltext; https://osaka-dent.repo.nii.ac.jp/?action=repository_action_common_download&item_id=338&item_no=1&attribute_id=20&file_no=1; https://osaka-dent.repo.nii.ac.jp/?action=repository_action_common_download&item_id=338&item_no=1&attribute_id=20&file_no=2
• オンライン閲覧公開範囲: インターネット公開
• 連携機関・データベース: 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• 提供元機関・データベース: 大阪歯科大学 : 大阪歯科大学学術リポジトリ