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Effect of Hepatitis C Virus Genotype 1b Core and NS5A Mutations on Response to Peginterferon Plus Ribavirin Combination Therapy

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Effect of Hepatitis C Virus Genotype 1b Core and NS5A Mutations on Response to Peginterferon Plus Ribavirin Combination Therapy

資料種別
記事
著者
Shingo Nakamotoほか
出版者
MDPI AG
出版年
2015-09-07
資料形態
デジタル
掲載誌名
International Journal of Molecular Sciences 16 9
掲載ページ
p.21177-21190
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資料詳細

要約等:

<jats:p>We examined whether hepatitis C virus (HCV) genotype 1b core- and NS5A-region mutations are associated with response to peginterferon α-2b plu...

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デジタル

資料種別
記事
出版年月日等
2015-09-07
出版年(W3CDTF)
2015-09-07
タイトル(掲載誌)
International Journal of Molecular Sciences
巻号年月日等(掲載誌)
16 9
掲載巻
16
掲載号
9
掲載ページ
21177-21190
掲載年月日(W3CDTF)
2015-09-07
出版事項(掲載誌)
MDPI AG
対象利用者
一般
標準番号(その他)
PMID : 26370958
作成日(W3CDTF)
2015-09-08
オンライン閲覧公開範囲
インターネット公開
著作権情報
https://creativecommons.org/licenses/by/4.0/
参照
Analysis of the complete open reading frame of hepatitis C virus in genotype 2a infection reveals critical sites influencing the response to peginterferon and ribavirin therapy
Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial
Amino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin†
Sustained virological response in hepatitis C virus type 1b infected patients is predicted by the number of mutations within the NS5A-ISDR: a meta-analysis focused on geographical differences
Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis.
Quantification of hepatitis C amino acid substitutions 70 and 91 in the core coding region by real-time amplification refractory mutation system reverse transcription-polymerase chain reaction
Expression of hepatitis c virus proteins inhibits interferon α signaling in the liver of transgenic mice
Expression of Hepatitis C Virus Proteins Inhibits Signal Transduction through the Jak-STAT Pathway
Classification of chronic hepatitis: Diagnosis, grading and staging
Peginterferon-α2a and Ribavirin Combination Therapy in Chronic Hepatitis C
Predictive values of amino acid sequences of the core and NS5A regions in antiviral therapy for hepatitis C: a Japanese multi-center study
Mutations in the Hepatitis C Virus <i>core</i> Gene Are Associated with Advanced Liver Disease and Hepatocellular Carcinoma
Association between mutations in the core region of hepatitis C virus genotype 1 and hepatocellular carcinoma development
Peginterferon Alfa-2a plus Ribavirin for Chronic Hepatitis C Virus Infection
Mutations in E2-PePHD, NS5A-PKRBD, NS5A-ISDR, and NS5A-V3 of Hepatitis C Virus Genotype 1 and Their Relationships to Pegylated Interferon-Ribavirin Treatment Responses
Endogenous intrahepatic IFNs and association with IFN-free HCV treatment outcome
Impact of Asian Race on Response to Combination Therapy With Peginterferon Alfa-2a and Ribavirin in Chronic Hepatitis C
Viral hepatitis C
Amino acid substitutions in the hepatitis C virus core region are the important predictor of hepatocarcinogenesis
IFN‐α antagonistic activity of HCV core protein involves induction of suppressor of cytokine signaling‐3
Hepatitis C Virus Nonstructural 5A Protein and Interferon Resistance: a New Model for Testing the Reliability of Mutational Analyses
Anemia in the Treatment of Hepatitis C Virus Infection
Predictive factors of early and sustained responses to peginterferon plus ribavirin combination therapy in Japanese patients infected with hepatitis C virus genotype 1b: Amino acid substitutions in the core region and low-density lipoprotein cholesterol levels
Treatment predictors of a sustained virologic response in hepatitis B and C
Mutations in the Nonstructural Protein 5a Gene and Response to Interferon in Patients with Chronic Hepatitis C Virus 1b Infection
Impact of amino acid substitutions in the hepatitis C virus genotype 1b core region on liver steatosis and hepatic oxidative stress in patients with chronic hepatitis C
Locations of antibody binding sites within conserved regions of the hepatitis C virus core protein
Viral Determinants of Resistance to Treatment in Patients with Hepatitis C
Evidence That Hepatitis C Virus Resistance to Interferon Is Mediated through Repression of the PKR Protein Kinase by the Nonstructural 5A Protein
Virological Response in Patients with??Hepatitis C Virus Genotype 1b and??a??High Viral Load
Homotypic Interaction and Multimerization of Hepatitis C Virus Core Protein
Mechanism of action of interferon and ribavirin in treatment of hepatitis C
Transcriptional regulation of cellular and viral promoters by the hepatitis C virus core protein
New hepatitis C virus (HCV) genotyping system that allows for identification of HCV genotypes 1a, 1b, 2a, 2b, 3a, 3b, 4, 5a, and 6a
Control of PKR Protein Kinase by Hepatitis C Virus Nonstructural 5A Protein: Molecular Mechanisms of Kinase Regulation
Peginterferon alfa-2b and Ribavirin: Effective in Patients With Hepatitis C Who Failed Interferon alfa/Ribavirin Therapy
Pretreatment Sequence Diversity Differences in the Full-Length Hepatitis C Virus Open Reading Frame Correlate with Early Response to Therapy
Mutations in the E2–Pephd and Ns5a Region of Hepatitis C Virus Type 1 and the Dynamics of Hepatitis C Viremia Decline During Interferon Alfa Treatment
Comparison of full-length sequences of interferon-sensitive and resistant hepatitis C virus 1b. Sensitivity to interferon is conferred by amino acid substitutions in the NS5A region.
Optimal therapy of hepatitis C
Natural history of chronic hepatitis C
Internal Initiation Stimulates Production of p8 Minicore, a Member of a Newly Discovered Family of Hepatitis C Virus Core Protein Isoforms
Serum aminotransferase levels and platelet counts as predictors of degree of fibrosis in chronic hepatitis C virus infection
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提供元機関・データベース
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