Effect of Hepatitis C Virus Genotype 1b Core and NS5A Mutations on Response to Peginterferon Plus Ribavirin Combination Therapy
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CiNii Research
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- 資料種別
- 記事
- 著者標目
- 出版年月日等
- 2015-09-07
- 出版年(W3CDTF)
- 2015-09-07
- タイトル(掲載誌)
- International Journal of Molecular Sciences
- 巻号年月日等(掲載誌)
- 16 9
- 掲載巻
- 16
- 掲載号
- 9
- 掲載ページ
- 21177-21190
- 掲載年月日(W3CDTF)
- 2015-09-07
- 出版事項(掲載誌)
- MDPI AG
- 件名標目
- 対象利用者
- 一般
- 標準番号(その他)
- PMID : 26370958
- DOI
- 10.3390/ijms160921177
- 作成日(W3CDTF)
- 2015-09-08
- オンライン閲覧公開範囲
- インターネット公開
- 著作権情報
- https://creativecommons.org/licenses/by/4.0/
- 参照
- Analysis of the complete open reading frame of hepatitis C virus in genotype 2a infection reveals critical sites influencing the response to peginterferon and ribavirin therapyPeginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trialAmino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin†Sustained virological response in hepatitis C virus type 1b infected patients is predicted by the number of mutations within the NS5A-ISDR: a meta-analysis focused on geographical differencesMolecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis.Quantification of hepatitis C amino acid substitutions 70 and 91 in the core coding region by real-time amplification refractory mutation system reverse transcription-polymerase chain reactionExpression of hepatitis c virus proteins inhibits interferon α signaling in the liver of transgenic miceExpression of Hepatitis C Virus Proteins Inhibits Signal Transduction through the Jak-STAT PathwayClassification of chronic hepatitis: Diagnosis, grading and stagingPeginterferon-α2a and Ribavirin Combination Therapy in Chronic Hepatitis CPredictive values of amino acid sequences of the core and NS5A regions in antiviral therapy for hepatitis C: a Japanese multi-center studyMutations in the Hepatitis C Virus <i>core</i> Gene Are Associated with Advanced Liver Disease and Hepatocellular CarcinomaAssociation between mutations in the core region of hepatitis C virus genotype 1 and hepatocellular carcinoma developmentPeginterferon Alfa-2a plus Ribavirin for Chronic Hepatitis C Virus InfectionMutations in E2-PePHD, NS5A-PKRBD, NS5A-ISDR, and NS5A-V3 of Hepatitis C Virus Genotype 1 and Their Relationships to Pegylated Interferon-Ribavirin Treatment ResponsesEndogenous intrahepatic IFNs and association with IFN-free HCV treatment outcomeImpact of Asian Race on Response to Combination Therapy With Peginterferon Alfa-2a and Ribavirin in Chronic Hepatitis CViral hepatitis CAmino acid substitutions in the hepatitis C virus core region are the important predictor of hepatocarcinogenesisIFN‐α antagonistic activity of HCV core protein involves induction of suppressor of cytokine signaling‐3Hepatitis C Virus Nonstructural 5A Protein and Interferon Resistance: a New Model for Testing the Reliability of Mutational AnalysesAnemia in the Treatment of Hepatitis C Virus InfectionPredictive factors of early and sustained responses to peginterferon plus ribavirin combination therapy in Japanese patients infected with hepatitis C virus genotype 1b: Amino acid substitutions in the core region and low-density lipoprotein cholesterol levelsTreatment predictors of a sustained virologic response in hepatitis B and CMutations in the Nonstructural Protein 5a Gene and Response to Interferon in Patients with Chronic Hepatitis C Virus 1b InfectionImpact of amino acid substitutions in the hepatitis C virus genotype 1b core region on liver steatosis and hepatic oxidative stress in patients with chronic hepatitis CLocations of antibody binding sites within conserved regions of the hepatitis C virus core proteinViral Determinants of Resistance to Treatment in Patients with Hepatitis CEvidence That Hepatitis C Virus Resistance to Interferon Is Mediated through Repression of the PKR Protein Kinase by the Nonstructural 5A ProteinVirological Response in Patients with??Hepatitis C Virus Genotype 1b and??a??High Viral LoadHomotypic Interaction and Multimerization of Hepatitis C Virus Core ProteinMechanism of action of interferon and ribavirin in treatment of hepatitis CTranscriptional regulation of cellular and viral promoters by the hepatitis C virus core proteinNew hepatitis C virus (HCV) genotyping system that allows for identification of HCV genotypes 1a, 1b, 2a, 2b, 3a, 3b, 4, 5a, and 6aControl of PKR Protein Kinase by Hepatitis C Virus Nonstructural 5A Protein: Molecular Mechanisms of Kinase RegulationPeginterferon alfa-2b and Ribavirin: Effective in Patients With Hepatitis C Who Failed Interferon alfa/Ribavirin TherapyPretreatment Sequence Diversity Differences in the Full-Length Hepatitis C Virus Open Reading Frame Correlate with Early Response to TherapyMutations in the E2–Pephd and Ns5a Region of Hepatitis C Virus Type 1 and the Dynamics of Hepatitis C Viremia Decline During Interferon Alfa TreatmentComparison of full-length sequences of interferon-sensitive and resistant hepatitis C virus 1b. Sensitivity to interferon is conferred by amino acid substitutions in the NS5A region.Optimal therapy of hepatitis CNatural history of chronic hepatitis CInternal Initiation Stimulates Production of p8 Minicore, a Member of a Newly Discovered Family of Hepatitis C Virus Core Protein IsoformsSerum aminotransferase levels and platelet counts as predictors of degree of fibrosis in chronic hepatitis C virus infection
- 連携機関・データベース
- 国立情報学研究所 : CiNii Research
- 提供元機関・データベース
- Crossref科学研究費助成事業データベース