記事
Stage-Specific Effects of Ionizing Radiation during Early Development
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CiNii Research
Stage-Specific Effects of Ionizing Radiation during Early Development
- 資料種別
- 記事
- 著者
- Yasuko Honjoほか
- 出版者
- MDPI AG
- 出版年
- 2020-06-01
- 資料形態
- デジタル
- 掲載誌名
- International Journal of Molecular Sciences 21 11
- 掲載ページ
- p.3975-
資料詳細
要約等:
- <jats:p>Early embryonic cells are sensitive to genotoxic stressors such as ionizing radiation. However, sensitivity to these stressors varies dependin...
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デジタル
- 資料種別
- 記事
- 出版年月日等
- 2020-06-01
- 出版年(W3CDTF)
- 2020-06-01
- タイトル(掲載誌)
- International Journal of Molecular Sciences
- 巻号年月日等(掲載誌)
- 21 11
- 掲載巻
- 21
- 掲載号
- 11
- 掲載ページ
- 3975-
- 掲載年月日(W3CDTF)
- 2020-06-01
- 出版事項(掲載誌)
- MDPI AG
- 件名標目
- 対象利用者
- 一般
- 標準番号(その他)
- PMID : 32492918
- DOI
- 10.3390/ijms21113975
- 作成日(W3CDTF)
- 2020-06-02
- オンライン閲覧公開範囲
- インターネット公開
- 著作権情報
- https://creativecommons.org/licenses/by/4.0/
- 参照
- Cell cycle-dependent radiosensitivity in mouse zygotesEffect of microgravity on mammalian embryo development evaluated at the International Space StationEffect of gamma-ray exposure on the genome-editing efficiency of improved genome-editing via oviductal nucleic acids delivery (<i>i</i>-GONAD)
- 参照
- Developmental Activation of the Capability to Undergo Checkpoint-Induced Apoptosis in the Early Zebrafish EmbryoSEQUELAE OF THE LD/50 X-RAY EXPOSURE OF THE PRE-IMPLANTATION MOUSE EMBRYO: DAYS 0.0 TO 5.0Histone titration against the genome sets the DNA-to-cytoplasm threshold for the <i>Xenopus</i> midblastula transitionEmbryonic death, dwarfism and fetal malformations after irradiation of embryos at the zygote stage: studies on two mouse strainsRole of cell cycle in mediating sensitivity to radiotherapyDisruption of <i>mRad50</i> causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiationIdentification of radiation-sensitive mutants in the Medaka, Oryzias latipesChk1 and Chk2 kinases in checkpoint control and cancerLack of a <i> p21 <sup>waf1/cip</sup> </i> ‐Dependent G1/S Checkpoint in Neural Stem and Progenitor Cells After DNA Damage In VivoDynamic Dependence on ATR and ATM for Double-Strand Break Repair in Human Embryonic Stem Cells and Neural DescendantsA Comparison of the X-Ray Sensitivity of Haploid and Diploid Zygotes of Xenopus IaevisCellular responses to ionizing radiation change quickly over time during early development in zebrafishLoss of <i>p</i> 21 increases sensitivity to ionizing radiation and delays the onset of lymphoma in <i>atm</i> -deficient miceMechanisms maintaining genomic integrity in embryonic stem cells and induced pluripotent stem cellsCdks and cyclins link G<sub>1</sub>length and differentiation of embryonic, neural and hematopoietic stem cellsThe Embryonic and Fetal Effects in ICR Mice Irradiated in the Various Stages of the Preimplantation PeriodUndamaged DNA Transmits and Enhances DNA Damage Checkpoint Signals in Early EmbryosG1 checkpoint is compromised in mouse ESCs due to functional uncoupling of p53-p21Waf1 signalingHomologous Recombination in Zebrafish ES CellsNovel use of zebrafish as a vertebrate model to screen radiation protectors and sensitizersDeconstructing stem cell self-renewal: genetic insights into cell-cycle regulationDNA double‐strand break response in stem cells: Mechanisms to maintain genomic integrityThe role of nucleotide excision repair in protecting embryonic stem cells from genotoxic effects of UV-induced DNA damageStress Defense in Murine Embryonic Stem Cells Is Superior to That of Various Differentiated Murine CellsHomologous Recombination and DNA-End Joining Reactions in Zygotes and Early Embryos of Zebrafish <i>(Danio rerio) </i>and <i>Drosophila melanogaster</i>Chk2-deficient mice exhibit radioresistance and defective p53-mediated transcriptionMouse embryonic stem cells are hypersensitive to apoptosis triggered by the DNA damage O6-methylguanine due to high E2F1 regulated mismatch repairDNA repair activity in fish and interest in ecotoxicology: A reviewCell Cycle-Dependent Radiosensitivity in Two-Cell Mouse Embryos in CultureNuclear accumulation and activation of p53 in embryonic stem cells after DNA damageSurvival responses of human embryonic stem cells to DNA damageChk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functionalA developmental timer that regulates apoptosis at the onset of gastrulationEffect of Heat on Radiosensitivity at Different Developmental Stages of Embryos of the Fish<i>Oryzias Latipes</i>Gamma radiation induces locus specific changes to histone modification enrichment in zebrafish and Atlantic salmonDelayed and stage specific phosphorylation of H2AX during preimplantation development of γ-irradiated mouse embryosEffect of inhibitors of DNA replication on early zebrafish embryos: evidence for coordinate activation of multiple intrinsic cell-cycle checkpoints at the mid-blastula transitionAberrant cell cycle checkpoint function and early embryonic death in <i>Chk1</i><sup>−/−</sup> miceRBE of Fast Neutrons for Inhibition of Hatchability in Fish Embryos Irradiated at Different Developmental StagesDNA repair capacity of zebrafishDNA Damage Responses in Human Induced Pluripotent Stem Cells and Embryonic Stem CellsActivation of apoptosis and caspase‐3 in zebrafish early gastrulaeThe <i>Xenopus</i> Chk1 Protein Kinase Mediates a Caffeine-sensitive Pathway of Checkpoint Control in Cell-free ExtractsPleiotropic defects in ataxia-telangiectasia protein-deficient miceSome Biochemical Consequences of the Spatial Distribution of Ionizing Radiation-Produced Free RadicalsRadiation effects on development<i>ATR</i> disruption leads to chromosomal fragmentation and early embryonic lethalityRadiosensitivity variation during the cell cycle in pronuclear mouse embryos <i>in vitro</i>An analysis of the changing radiation response of the developing mouse embryoDeficiency in the response to DNA double-strand breaks in mouse early preimplantation embryosRadiation-sensitivity Differences within Cell-division Cycles during Mouse CleavageInhibition of cyclin-dependent kinase 2 by p21 is necessary for retinoblastoma protein-mediated G <sub>1</sub> arrest after γ-irradiationAnalysis of Structural and Numerical Chromosomal Anomalies at the First, Second, and Third Mitosis after Irradiation of One-cell Mouse Embryos with X-rays or NeutronsDNA Damage-Induced Activation of p53 by the Checkpoint Kinase Chk2The One-cell Mouse Embryo: Cell Cycle-dependent Radiosensitivity and Development of Chromosomal Anomalies in Postradiation Cell CyclesThe medaka midblastula transition as revealed by the expression of the paternal genomeHighly Asynchronous and Asymmetric Cleavage Divisions Accompany Early Transcriptional Activity in Pre-Blastula Medaka EmbryosChk1 is an essential kinase that is regulated by Atr and required for the G<sub>2</sub>/M DNA damage checkpointThe effects of ionising radiation on the embryo and foetus: A review of experimental dataX-Ray Sensitivity during the Cell Generation Cycle of Cultured Chinese Hamster CellsRestoration of an absent G <sub>1</sub> arrest and protection from apoptosis in embryonic stem cells after ionizing radiationIonizing radiation induces apoptosis and elevates cyclin A1-Cdk2 activity before but not after the midblastula transition in Xenopus.Homologous Recombination Conserves DNA Sequence Integrity Throughout the Cell Cycle in Embryonic Stem CellsPrenatal irradiation–induced brain neuropathology and cognitive impairmentInduction and Repair of Clustered DNA Lesions: What Do We Know So Far?p53 and p73 Regulate Apoptosis but Not Cell-Cycle Progression in Mouse Embryonic Stem Cells upon DNA Damage and DifferentiationMaintenance of Genomic Stability in Mouse Embryonic Stem Cells: Relevance in Aging and DiseaseThe Cell Cycle and Myc Intersect with Mechanisms that Regulate Pluripotency and ReprogrammingMarked depression of time interval between fertilization period and hatching period following exposure to low-dose X-rays in zebrafishES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damagep21--Negative Regulator of the Cell CyclePreliminary study on chromosomal aberrations in eggs of mice fertilized in vitro after X-irradiationDNA damage signaling in early Xenopus embryosHypersensitivity to DNA damage leads to increased apoptosis during early mouse developmentLethal and teratogenic effects after exposure to X‐rays at various times of early murine gestationThe DNA Damage Checkpoint in Embryonic Cell Cycles Is Dependent on the DNA-to-Cytoplasmic RatioMouse Embryonic Stem Cells, but Not Somatic Cells, Predominantly Use Homologous Recombination to Repair Double-Strand DNA BreaksMitotic and G <sub>2</sub> Checkpoint Control: Regulation of 14-3-3 Protein Binding by Phosphorylation of Cdc25C on Serine-216Repair at Single Targeted DNA Double-Strand Breaks in Pluripotent and Differentiated Human CellsEffects of Radiations of Different Qualities on Cells: Molecular Mechanisms of Damage and RepairCell cycle regulation during early mouse embryogenesisIonizing Radiation Induces Ataxia Telangiectasia Mutated-Dependent Checkpoint Signaling and G2 But Not G1 Cell Cycle Arrest in Pluripotent Human Embryonic Stem CellsNbn Heterozygosity Renders Mice Susceptible to Tumor Formation and Ionizing Radiation-Induced TumorigenesisMalformations after radiation exposure of preimplantation stagesBiological effects after prenatal irradiation (embryo and fetus) ICRP Publication 90 Approved by the Commission in October 2002X-Ray Effect on the Development of Xenopus laevis Embryos —With Special Reference to Primordial Germ CellsChange in Dose-survival Time Relationship after X-irradiation during Embryonic Development in the Fish, Oryzias IatipesCell Lines Derived from a Medaka Radiation-Sensitive Mutant have Defects in DNA Double-Strand Break Responses
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