Impact of Different Selectivity between Soluble and Membrane-bound Forms of Carcinoembryonic Antigen (CEA) on the Target-mediated Disposition of Anti-CEA Monoclonal Antibodies

• 資料種別: 記事
• タイトル: Impact of Different Selectivity between Soluble and Membrane-bound Forms of Carcinoembryonic Antigen (CEA) on the Target-mediated Disposition of Anti-CEA Monoclonal Antibodies
• 著者標目: Junko Iwano; Daisuke Shinmi; https://orcid.org/0000-0001-6706-0030; Kazuhiro Masuda; Takashi Murakami; Junichi Enokizono; https://orcid.org/0009-0006-8898-835x
• 出版年月日等: 2019-11
• 出版年（W3CDTF）: 2019-11
• タイトル（掲載誌）: Drug Metabolism and Disposition
• 巻号年月日等（掲載誌）: 47 11
• 掲載巻: 47
• 掲載号: 11
• 掲載ページ: 1240-1246
• 掲載年月日（W3CDTF）: 2019-11
• ISSN（掲載誌）: 00909556
• 出版事項（掲載誌）: Elsevier BV
• 件名標目: Male; Mice, Inbred BALB C; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Carcinoembryonic Antigen; Mice; Liver; Area Under Curve; Animals
• 対象利用者: 一般
• 標準番号（その他）: PMID : 31533926
• DOI: 10.1124/dmd.119.088179
• 作成日（W3CDTF）: 2019-09-18
• オンライン閲覧公開範囲: インターネット公開
• 著作権情報: https://www.elsevier.com/tdm/userlicense/1.0/; https://www.elsevier.com/legal/tdmrep-license
• 関連情報（URI）: https://api.elsevier.com/content/article/PII:S0090955624077110?httpAccept=text/xml; https://api.elsevier.com/content/article/PII:S0090955624077110?httpAccept=text/plain; https://syndication.highwire.org/content/doi/10.1124/dmd.119.088179
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• 連携機関・データベース: 国立情報学研究所 : CiNii Research; https://cir.nii.ac.jp/
• 提供元機関・データベース: Crossref; https://www.crossref.org; 科学研究費助成事業データベース; https://kaken.nii.ac.jp/ja

• 要約等: Carcinoembryonic antigen (CEA) is a tumor-specific antigen overexpressed in multiple cancers. CEA is expressed as a membrane protein, a part of which ...