Hypoxia Modifies the Transcriptome of Human NK Cells, Modulates Their Immunoregulatory Profile, and Influences NK Cell Subset Migration

• 資料種別: 記事
• タイトル: Hypoxia Modifies the Transcriptome of Human NK Cells, Modulates Their Immunoregulatory Profile, and Influences NK Cell Subset Migration
• 著者標目: Monica Parodi; https://orcid.org/0000-0001-9606-2190; Federica Raggi; https://orcid.org/0000-0002-6089-1752; Davide Cangelosi; https://orcid.org/0000-0002-6010-5619; Claudia Manzini; Mirna Balsamo; Fabiola Blengio; Alessandra Eva; https://orcid.org/0000-0003-2949-078x; Luigi Varesio; Gabriella Pietra; https://orcid.org/0000-0002-7080-531x; Lorenzo Moretta; https://orcid.org/0000-0003-4658-1747; Maria Cristina Mingari; Massimo Vitale; https://orcid.org/0000-0001-5372-7885; Maria Carla Bosco; https://orcid.org/0000-0003-1857-7193
• 出版年月日等: 2018-10-16
• 出版年（W3CDTF）: 2018-10-16
• タイトル（掲載誌）: Frontiers in Immunology
• 巻号年月日等（掲載誌）: 9
• 掲載巻: 9
• 掲載年月日（W3CDTF）: 2018-10-16
• 出版事項（掲載誌）: Frontiers Media SA
• 件名標目: Immunology; chemokine receptors; NK cells; Lymphocyte Activation; CD56bright cells; Chemokine receptors; Cytokines/chemokines; Hypoxia; NK cells; Transcriptome; Tumor immunology; Tumor infiltration; Cell Differentiation; Cell Movement; Chemotaxis; Cytokines; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation; Humans; Hypoxia; Immunomodulation; Killer Cells, Natural; Lymphocyte Activation; Transcriptome; CD56bright cells, Chemokine receptors, Cytokines/chemokines, Hypoxia, NK cells, Transcriptome, Tumor immunology, Tumor infiltration, Immunology and Allergy, Immunology; Immunomodulation; CD56bright cells; Cell Movement; Humans; tumor immunology; Hypoxia; hypoxia; Chemotaxis; Gene Expression Profiling; Cell Differentiation; RC581-607; cytokines/chemokines; Flow Cytometry; Killer Cells, Natural; Gene Expression Regulation; Cytokines; Immunologic diseases. Allergy; Transcriptome
• 対象利用者: 一般
• 標準番号（その他）: PMID : 30459756
• DOI: 10.3389/fimmu.2018.02358
• 作成日（W3CDTF）: 2018-10-16
• オンライン閲覧公開範囲: インターネット公開
• 著作権情報: https://creativecommons.org/licenses/by/4.0/
• 関連情報（URI）: https://www.frontiersin.org/article/10.3389/fimmu.2018.02358/full; http://hdl.handle.net/11567/931906; http://hdl.handle.net/2318/1806534
• 参照: Transcriptomic Changes in Young Japanese Males After Exposure to Acute Hypobaric Hypoxia; https://cir.nii.ac.jp/crid/1360853567725382400
• 参照: Faculty Opinions recommendation of Hypoxia modulates the gene expression profile of immunoregulatory receptors in human mature dendritic cells: identification of TREM-1 as a novel hypoxic marker in vitro and in vivo.; https://cir.nii.ac.jp/crid/1884242817486698880
• 連携機関・データベース: 国立情報学研究所 : CiNii Research; https://cir.nii.ac.jp/
• 提供元機関・データベース: Crossref; https://www.crossref.org

• 要約等: Hypoxia, which characterizes most tumor tissues, can alter the function of different immune cell types, favoring tumor escape mechanisms. In this stud...