Requirement for the Kinase Activity of Human DNA-Dependent Protein Kinase Catalytic Subunit in DNA Strand Break Rejoining

• 資料種別: 記事
• タイトル: Requirement for the Kinase Activity of Human DNA-Dependent Protein Kinase Catalytic Subunit in DNA Strand Break Rejoining
• 著者標目: Akihiro Kurimasa; Satoshi Kumano; Nikolai V. Boubnov; Michael D. Story; Chang-Shung Tung; Scott R. Peterson; David J. Chen
• 出版年月日等: 1999-05-01
• 出版年（W3CDTF）: 1999-05-01
• タイトル（掲載誌）: Molecular and Cellular Biology
• 巻号年月日等（掲載誌）: 19 5
• 掲載巻: 19
• 掲載号: 5
• 掲載ページ: 3877-3884
• 掲載年月日（W3CDTF）: 1999-05-01
• 出版事項（掲載誌）: Informa UK Limited
• 件名標目: Models, Molecular; Recombination, Genetic; Binding Sites; DNA Repair; Genes, Immunoglobulin; Molecular Sequence Data; Gene Expression; Nuclear Proteins; DNA-Activated Protein Kinase; Protein Serine-Threonine Kinases; Cyclic AMP-Dependent Protein Kinases; Recombinant Proteins; DNA-Binding Proteins; Phosphatidylinositol 3-Kinases; Adenosine Triphosphate; Tumor Cells, Cultured; Humans; Amino Acid Sequence; Sequence Alignment; DNA Damage
• 対象利用者: 一般
• 標準番号（その他）: PMID : 10207111
• DOI: 10.1128/mcb.19.5.3877; https://doi.org/10.1128/mcb.19.5.3877
• 作成日（W3CDTF）: 2015-10-26
• オンライン閲覧公開範囲: インターネット公開
• 著作権情報: https://journals.asm.org/non-commercial-tdm-license
• 関連情報（URI）: https://journals.asm.org/doi/pdf/10.1128/MCB.19.5.3877; https://www.tandfonline.com/doi/pdf/10.1128/MCB.19.5.3877
• 参照: Heat exposure enhances radiosensitivity by depressing DNA-PK kinase activity during double strand break repair; https://cir.nii.ac.jp/crid/1360002220502472576; DNA-Dependent Protein Kinase Catalytic Subunit: The Sensor for DNA Double-Strand Breaks Structurally and Functionally Related to Ataxia Telangiectasia Mutated; https://cir.nii.ac.jp/crid/1360013168838858752; NK314 potentiates antitumor activity with adult T-cell leukemia-lymphoma cells by inhibition of dual targets on topoisomerase IIα and DNA-dependent protein kinase; https://cir.nii.ac.jp/crid/1360283693931291392; Differential Radiosensitivity Phenotypes of DNA-PKcs Mutations Affecting NHEJ and HRR Systems following Irradiation with Gamma-Rays or Very Low Fluences of Alpha Particles; https://cir.nii.ac.jp/crid/1360285712521299328; Differential Role of DNA-PKcs Phosphorylations and Kinase Activity in Radiosensitivity and Chromosomal Instability; https://cir.nii.ac.jp/crid/1360285713105521920; Development and Evolution of DNA-Dependent Protein Kinase Inhibitors toward Cancer Therapy; https://cir.nii.ac.jp/crid/1360576283460470400
• 連携機関・データベース: 国立情報学研究所 : CiNii Research; https://cir.nii.ac.jp/
• 提供元機関・データベース: Crossref; https://www.crossref.org

• 要約等: The catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) is an enormous, 470-kDa protein serine/threonine kinase that has homology with member...