Xanthine Oxidase Inhibition by Febuxostat Attenuates Experimental Atherosclerosis in Mice

• 資料種別: 記事
• タイトル: Xanthine Oxidase Inhibition by Febuxostat Attenuates Experimental Atherosclerosis in Mice
• 著者標目: Johji Nomura; Nathalie Busso; Annette Ives; Chieko Matsui; Syunsuke Tsujimoto; Takashi Shirakura; Mizuho Tamura; Tsunefumi Kobayashi; Alexander So; Yoshihiro Yamanaka
• 出版年月日等: 2014-04-01
• 出版年（W3CDTF）: 2014-04-01
• タイトル（掲載誌）: Scientific Reports
• 巻号年月日等（掲載誌）: 4 1
• 掲載巻: 4
• 掲載号: 1
• 掲載ページ: 4554-
• 掲載年月日（W3CDTF）: 2014-04-01
• 出版事項（掲載誌）: Springer Science and Business Media LLC
• 対象利用者: 一般
• DOI: 10.1038/srep04554; https://doi.org/10.1038/srep04554
• 作成日（W3CDTF）: 2014-04-01
• 著作権情報: https://creativecommons.org/licenses/by/3.0/
• 関連情報（URI）: https://www.nature.com/articles/srep04554.pdf; https://www.nature.com/articles/srep04554
• 参照: Febuxostat does not delay progression of carotid atherosclerosis in patients with asymptomatic hyperuricemia : A randomized, controlled trial; https://cir.nii.ac.jp/crid/1050852514686743936; Xanthine Oxidase Inhibitor Febuxostat Exerts an Anti-Inflammatory Action and Protects against Diabetic Nephropathy Development in KK-Ay Obese Diabetic Mice; https://cir.nii.ac.jp/crid/1360005744308071808; Febuxostat treatment attenuates oxidative stress and inflammation due to ischemia-reperfusion injury through the necrotic pathway in skin flap of animal model; https://cir.nii.ac.jp/crid/1360013168811562496; The Effects of Xanthine Oxidoreductase Inhibitors on Oxidative Stress Markers following Global Brain Ischemia Reperfusion Injury in C57BL/6 Mice; https://cir.nii.ac.jp/crid/1360283694437095680; Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis; https://cir.nii.ac.jp/crid/1360285711330818048; The Xanthine Oxidase Inhibitor Febuxostat Suppresses the Progression of IgA Nephropathy, Possibly via Its Anti-Inflammatory and Anti-Fibrotic Effects in the gddY Mouse Model; https://cir.nii.ac.jp/crid/1360285714472202112; Febuxostat Attenuates the Progression of Periodontitis in Rats; https://cir.nii.ac.jp/crid/1360290617722537344; Urate-lowering therapy for CKD patients with asymptomatic hyperuricemia without proteinuria elucidated by attribute-based research in the FEATHER Study; https://cir.nii.ac.jp/crid/1360298336564118272; Allopurinol, Febuxostat, and Nonuse of Xanthine Oxidoreductase Inhibitor Treatment in Patients Receiving Hemodialysis: A Longitudinal Analysis; https://cir.nii.ac.jp/crid/1360303972864697344; Significance and amplification methods of the purine salvage pathway in human brain cells; https://cir.nii.ac.jp/crid/1360306905178736384; XOR-Derived ROS in Tie2-Lineage Cells Including Endothelial Cells Promotes Aortic Aneurysm Progression in Marfan Syndrome; https://cir.nii.ac.jp/crid/1360306905627405184; Increased plasma XOR activity induced by NAFLD/NASH and its possible involvement in vascular neointimal proliferation; https://cir.nii.ac.jp/crid/1360576118762622208; Febuxostat reduces muscle wasting in tumor-bearing mice with LM8 osteosarcoma cells via inhibition of reactive oxygen species generation; https://cir.nii.ac.jp/crid/1360576118763908864; Xanthine oxidase inhibition by febuxostat attenuates stress-induced hyperuricemia, glucose dysmetabolism, and prothrombotic state in mice; https://cir.nii.ac.jp/crid/1360848658407166848; Xanthine Oxidase Inhibition by Febuxostat in Macrophages Suppresses Angiotensin II-Induced Aortic Fibrosis; https://cir.nii.ac.jp/crid/1360848659450044544; Role of macrophage autophagy in atherosclerosis: modulation by bioactive compounds; https://cir.nii.ac.jp/crid/1360857593692915456; Impact of hyperuricemia on chronic kidney disease and atherosclerotic cardiovascular disease; https://cir.nii.ac.jp/crid/1360857593738881792; Association between serum urate level and carotid atherosclerosis: an insight from a post hoc analysis of the PRIZE randomised clinical trial; https://cir.nii.ac.jp/crid/1360862102147671296; Xanthine oxidase inhibitor ameliorates postischemic renal injury in mice by promoting resynthesis of adenine nucleotides; https://cir.nii.ac.jp/crid/1361412896469631744; Effect of the Xanthine Oxidase Inhibitor Febuxostat on the Cardio-Ankle Vascular Index in Asymptomatic Patients with Hyperuricemia and Liver Dysfunction: A Sub-Analysis of the PRIZE Study; https://cir.nii.ac.jp/crid/1390022222477279104; Impact of Serum Uric Acid Levels on Coronary Plaque Stability Evaluated Using Integrated Backscatter Intravascular Ultrasound in Patients with Coronary Artery Disease; https://cir.nii.ac.jp/crid/1390282679407406848; Cardiovascular significance of adipose-derived adiponectin and liver-derived xanthine oxidoreductase in metabolic syndrome; https://cir.nii.ac.jp/crid/1390578393608376320
• 連携機関・データベース: 国立情報学研究所 : CiNii Research; https://cir.nii.ac.jp/
• 提供元機関・データベース: Crossref; https://www.crossref.org

• 要約等: <jats:title>Abstract</jats:title><jats:p>Atherosclerosis is a chronic inflammatory disease due to lipid deposition in the arterial wall. Multiple mech...