Graphene Field-Effect Transistors with Surface-Charge Modulation for C-Reactive Protein Detection in Artificial Saliva
デジタルデータあり（科学技術振興機構）
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J-STAGE
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- 資料種別
- 記事
- 著者標目
- 出版年月日等
- 2024-03-23
- 出版年（W3CDTF）
- 2024-03-23
- タイトル（掲載誌）
- Electrochemistry
- 巻号年月日等（掲載誌）
- 92 3
- 掲載巻
- 92
- 掲載号
- 3
- 掲載ページ
- 037006-037006
- 掲載年月日（W3CDTF）
- 2024-03-23
- ISSN（掲載誌）
- 13443542
- ISSN-L（掲載誌）
- 13443542
- 出版事項（掲載誌）
- The Electrochemical Society of Japan
- 本文の言語コード
- en
- 対象利用者
- 一般
- DOI
- 10.5796/electrochemistry.24-00016
- オンライン閲覧公開範囲
- インターネット公開
- 参照
- Graphene as an Imaging Platform of Charged MoleculesDrift Suppression of Solution-Gated Graphene Field-Effect Transistors by Cation Doping for Sensing PlatformsReview on electrochemical sensing strategies for C-reactive protein and cardiac troponin I detectionSelective ion sensing with high resolution large area graphene field effect transistor arraysSelective single-molecule analytical detection of C-reactive protein in saliva with an organic transistorSurface Charge Modulation and Reduction of Non-Linear Electrolytic Screening in FET-Based BiosensingSemi-quantitative graphene chemiresistor enzyme immunoassay for simple and sensitive antigen detectionState-space modeling for dynamic response of graphene FET biosensorsDeep-learning-based semantic image segmentation of graphene field-effect transistorsValidation of a high-sensitivity assay for C-reactive protein in human salivaGraphene as a Reversible and Spectrally Selective Fluorescence QuencherDetection of Glial Fibrillary Acidic Protein in Patient Plasma Using On-Chip Graphene Field-Effect Biosensors, in Comparison with ELISA and Single-Molecule ArrayCarbon-Dot-Enhanced Graphene Field-Effect Transistors for Ultrasensitive Detection of ExosomesHigh throughput transfer technique: Save your graphenePoint-of-Care Diagnostics: Recent Developments in a Connected AgeBioanalytical advances in assays for C-reactive proteinNanosensor-Based Real-Time Monitoring of Stress Biomarkers in Human Saliva Using a Portable Measurement SystemElastomer-coated graphene biosensor and its response to enzymatic reactionsGraphene Sensor Arrays for Rapid and Accurate Detection of Pancreatic Cancer Exosomes in Patients’ Blood Plasma SamplesSurfactant-free single-layer graphene in waterSARS-CoV-2 detection by using graphene FET arrays with a portable microfluidic measurement systemRobust graphene field-effect transistor biosensors via hydrophobization of SiO<sub>2</sub> substratesBiosensing with Surface-Charge-Modulated Graphene Field-Effect Transistors beyond Nonlinear Electrolytic ScreeningEvaluation of saliva as diagnostic materials for influenza virus infection by PCR-based assaysCarrier Transport in Two-Dimensional Graphene LayersSaliva specimen: A new laboratory tool for diagnostic and basic investigationGraphene Field Effect Transistor-Based Immunosensor for Ultrasensitive Noncompetitive Detection of Small AntigensScalable Production of High-Sensitivity, Label-Free DNA Biosensors Based on Back-Gated Graphene Field Effect TransistorsA graphene-based physiometer array for the analysis of single biological cellsGraphene-based fully integrated portable nanosensing system for on-line detection of cytokine biomarkers in salivaRapid Detection of COVID-19 Causative Virus (SARS-CoV-2) in Human Nasopharyngeal Swab Specimens Using Field-Effect Transistor-Based BiosensorDetection of Cortisol in Saliva with a Flow-Filtered, Portable Surface Plasmon Resonance Biosensor SystemPerspectives on Carbon Nanotubes and Graphene Raman SpectroscopyTuning the isoelectric point of graphene by electrochemical functionalizationUltrahigh electron mobility in suspended grapheneChemical analysis in saliva and the search for salivary biomarkers – a tutorial reviewIonic strength-sensitive and pH-insensitive interactions between C-reactive protein (CRP) and an anti-CRP antibody
- 連携機関・データベース
- 国立情報学研究所 : CiNii Research
- 提供元機関・データベース
- Japan Link CenterCrossref
- 要約等
- <p>Saliva-based biosensors are emerging as viable tools for non-invasive, painless, and easily administered household medical diagnostics. Despite their potential, the complexity of saliva, containing various non-target molecules and contaminants, presents significant challenges due to nonspecific interactions with biosensors. This study utilizes surface-charge modulated graphene field-effect transistors (SCM-GFETs) for the detection of C-reactive protein (CRP) in artificial saliva, using portable measurement apparatus. Our findings indicate that SCM-GFETs exhibit nonspecific responses to saliva components. To address this issue, a two-step preprocessing method is implemented: diluting the saliva in phosphate-buffered saline at a 1 : 10<sup>4</sup> ratio and subsequent membrane filtration. This process significantly reduced nonspecific interactions, enabling CRP detection in saliva samples. These advancements hold promise for enhancing graphene field-effect transistor technology in point-of-care diagnostic devices.</p>
- DOI
- 10.5796/electrochemistry.24-00016
- オンライン閲覧公開範囲
- インターネット公開
- 連携機関・データベース
- 科学技術振興機構 : J-STAGE