Effect of capsaicin on voltage-gated sodium channels with <i>kdr</i> mutation from German cockroaches (<i>Blattella germanica</i>)

• 資料種別: 記事
• タイトル: Effect of capsaicin on voltage-gated sodium channels with <i>kdr</i> mutation from German cockroaches (<i>Blattella germanica</i>)
• 著者標目: Kamezaki Masashi; Nishiwaki Hisashi
• 出版年月日等: 2025-08-20
• 出版年（W3CDTF）: 2025-08-20
• タイトル（掲載誌）: 日本農薬学会誌（Ｊｏｕｒｎａｌ ｏｆ Ｐｅｓｔｉｃｉｄｅ Ｓｃｉｅｎｃｅ）
• 巻号年月日等（掲載誌）: 50 3
• 掲載巻: 50
• 掲載号: 3
• 掲載ページ: 74-80
• 掲載年月日（W3CDTF）: 2025-08-20
• ISSN（掲載誌）: 1348589X
• 出版事項（掲載誌）: Pesticide Science Society of Japan
• 本文の言語コード: en
• 件名標目: german cockroach; <i>kdr</i>; L993F; two-electrode voltage clamp; voltage-gated sodium channel
• 対象利用者: 一般
• DOI: 10.1584/jpestics.d25-023; https://doi.org/10.1584/jpestics.d25-023
• 関連情報（URI）: https://www.jstage.jst.go.jp/article/jpestics/50/3/50_D25-023/_pdf
• 参照: Genotype to phenotype, the molecular and physiological dimensions of resistance in arthropods; https://cir.nii.ac.jp/crid/1360011143931135872; A Single Crossing-Over Event in Voltage-Sensitive Na+ Channel Genes May Cause Critical Failure of Dengue Mosquito Control by Insecticides; https://cir.nii.ac.jp/crid/1360011144973390464; Differential mechanism of action of the pyrethroid tetramethrin on tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels.; https://cir.nii.ac.jp/crid/1360024023310328832; Sodium channel-directed alkaloids synergize the mosquitocidal and neurophysiological effects of natural pyrethrins; https://cir.nii.ac.jp/crid/1360024025244083072; A TRPV family ion channel required for hearing in Drosophila; https://cir.nii.ac.jp/crid/1360292619465116672; Leucine to tryptophane substitution in the pore helix IIP1 confer sodium channel resistance to pyrethroids and DDT; https://cir.nii.ac.jp/crid/1360305497317606528; Capsaicin Inhibits Multiple Voltage-Gated Ion Channels in Rabbit Ventricular Cardiomyocytes in TRPV1-Independent Manner; https://cir.nii.ac.jp/crid/1360305498299341952; Novel sodium channel gene mutations in Blattella germanica reduce the sensitivity of expressed channels to deltamethrin; https://cir.nii.ac.jp/crid/1360305498861421568; Cross resistance to brevetoxin-3 by kdr and super-kdr mutations in house flies; https://cir.nii.ac.jp/crid/1360305501693665152; Pyrethroids in an AlphaFold2 Model of the Insect Sodium Channel; https://cir.nii.ac.jp/crid/1360586972304169728; Mode of action of piperovatine, an insecticidal piperamide isolated from Piper piscatorum (Piperaceae), against voltage-gated sodium channels; https://cir.nii.ac.jp/crid/1360586972623903872; A single amino acid change in the para sodium channel protein is associated with knockdown-resistance (kdr) to pyrethroid insecticides in German cockroach; https://cir.nii.ac.jp/crid/1360586973263900288; Effect of Capsaicin and Other Thermo-TRP Agonists on Thermoregulatory Processes in the American Cockroach; https://cir.nii.ac.jp/crid/1360586974319394816; kdr-Type resistance in insects with special reference to the German cockroach, Blattella germanica; https://cir.nii.ac.jp/crid/1360586976725423488; Capsaicin Functions as Drosophila Ovipositional Repellent and Causes Intestinal Dysplasia; https://cir.nii.ac.jp/crid/1360865821277619200; Neuropharmacology and genetics of kdr-type resistance in the German cockroach, Blattella germanica (L.); https://cir.nii.ac.jp/crid/1360868448546322048; Capsaicin inhibits sodium currents and epileptiform activity in prefrontal cortex pyramidal neurons; https://cir.nii.ac.jp/crid/1360868449258473600; Insecticidal Activity of Natural Capsaicinoids Against Several Agricultural Insects; https://cir.nii.ac.jp/crid/1360868449278467584; Capsaicin preferentially inhibits slow-inactivation sodium currents in insects; https://cir.nii.ac.jp/crid/1360868451646788096; Transient receptor potential vanilloid 1 (TRPV1)‐independent actions of capsaicin on cellular excitability and ion transport; https://cir.nii.ac.jp/crid/1360868451652499968; Identification of Amino Acid Residues in the Insect Sodium Channel Critical for Pyrethroid Binding; https://cir.nii.ac.jp/crid/1360868451868910592; Capsaicin Inhibits Activation of Voltage-Gated Sodium Currents in Capsaicin-Sensitive Trigeminal Ganglion Neurons; https://cir.nii.ac.jp/crid/1361137045688447744; The capsaicin receptor: a heat-activated ion channel in the pain pathway; https://cir.nii.ac.jp/crid/1361137045885586432; <i>Drosophila</i>Painless Is a Ca²⁺-Requiring Channel Activated by Noxious Heat; https://cir.nii.ac.jp/crid/1361418520702862208; Two Interdependent TRPV Channel Subunits, Inactive and Nanchung, Mediate Hearing in <i>Drosophila</i>; https://cir.nii.ac.jp/crid/1361699993558873344; Preferential block of inactivation-deficient Na+ currents by capsaicin reveals a non-TRPV1 receptor within the Na+ channel; https://cir.nii.ac.jp/crid/1361981470978232064; Pyrethroids, knockdown resistance and sodium channels; https://cir.nii.ac.jp/crid/1361981471130443520; Activation of<i>Drosophila</i>Sodium Channels Promotes Modification by Deltamethrin; https://cir.nii.ac.jp/crid/1362262943955136896; Molecular evidence for dual pyrethroid-receptor sites on a mosquito sodium channel; https://cir.nii.ac.jp/crid/1362262944158522368; A Method of Computing the Effectiveness of an Insecticide; https://cir.nii.ac.jp/crid/1362544419085261184; Elucidation of pyrethroid and DDT receptor sites in the voltage-gated sodium channel; https://cir.nii.ac.jp/crid/1362825894492775936; Voltage-gated sodium channels as primary targets of diverse lipid-soluble neurotoxins; https://cir.nii.ac.jp/crid/1363388844308893056
• 連携機関・データベース: 国立情報学研究所 : CiNii Research; https://cir.nii.ac.jp/
• 提供元機関・データベース: Japan Link Center; https://japanlinkcenter.org/top; Crossref; https://www.crossref.org

• 要約等: <p>Capsaicin inhibits the current flow in the voltage-gated sodium channels (VGSCs) of mammals and insects. The aim of the present study was to elucid...