一体型SPECT/CT装置における心電図同期X線CT撮影の減弱補正法の確立

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Author: 小野口, 昌久ほか

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Publication date: 2017-05-17

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Note (General)：: 金沢大学医薬保健研究域保健学系外膜と内膜がそれぞれ任意に作動する新しい心臓動態ファントムを構築した。SPECT/CT装置を用い，ファントムの心筋層にTc-99m溶液，心室部に造影剤を入れて心機能評価の検証を行った。今回開発した本ファントムは，ストローク比を任意に変えることで異なる心筋壁の動きや左室容...

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https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26460725/

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Material Type: 文書・図像類
Title: 一体型SPECT/CT装置における心電図同期X線CT撮影の減弱補正法の確立
Author/Editor: 小野口, 昌久
Onoguchi, Masahisa
Author Heading: 小野口, 昌久
Onoguchi, Masahisa
Publication Date: 2017-05-17
Publication Date (W3CDTF): 2017-05-17
Alternative Title: Establishment of attenuation correction method using myocardial gated X-ray/CT imaging in integrated SPECT/CT system
Periodical title: 平成28(2016)年度科学研究費補助金基盤研究(C) 研究成果報告書 = 2016 Fiscal Year Final Research Report
No. or year of volume/issue: 2014-04-01 - 2017-03-31
Volume: 2014-04-01 - 2017-03-31
Pages: 4p.-
Text Language Code: jpn
Subject Heading: 心筋動態ファントム
心電図同期SPECT
SPECT/CT装置
減弱補正
心機能
心筋血流
心電図同期CT撮影法
被ばく線量
Target Audience: 一般
Note (General): 金沢大学医薬保健研究域保健学系
外膜と内膜がそれぞれ任意に作動する新しい心臓動態ファントムを構築した。SPECT/CT装置を用い，ファントムの心筋層にTc-99m溶液，心室部に造影剤を入れて心機能評価の検証を行った。今回開発した本ファントムは，ストローク比を任意に変えることで異なる心筋壁の動きや左室容積が可変できる。本ファントムを用いることで多様な臨床条件（心室容積，駆出率，物理的現象）を想定した技術的評価が可能と考えられた。
The conventional dynamic cardiac phantom used in the field of nuclear medicine has a structure for which the size of the external side of the heartis fixed and only the inner side moves anteroposterior. Therefore, its usefulness in technical evaluation is limited. Hence, we developed a new dynamic cardiac phantom in which the outer and inner membranes freely move. Using a SPECT/CT system, we performed validation by filling the myocardial layer of the dynamic cardiac phantom with solution and the ventricle part with contrast medium. We evaluated myocardial wall motions of 3 segments (basal, mid, and apical) by setting the stroke ratios at 20:20 (ventricle-to-myocardial layer ratio). The myocardial wall motions at the stroke ratio of 20:20 were 7.50 ± 0.44, 11.15 ± 0.56, and 9.90 ± 0.24 mm in the basal, mid, and apical segments, respectively. These results suggest that the use of this phantom can realize technical evaluation that presumes various clinical conditions.
研究課題/領域番号:26460725, 研究期間(年度):2014-04-01 - 2017-03-31
DOI: 10.24517/00053200
Access Restrictions: 限定公開
Related Material: https://kaken.nii.ac.jp/search/?qm=30283120
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26460725/
https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-26460725/26460725seika/
Data Provider (Database): 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）
https://irdb.nii.ac.jp
Original Data Provider (Database): 金沢大学 : 金沢大学学術情報リポジトリKURA