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Ara-Cの白血病細胞内活性化物高感度モニターによる抗がん効果の予測

Ara-Cの白血病細胞内活性化物高感度モニターによる抗がん効果の予測
Paper図書
上田, 孝典, 福井医科大学1998-2001<Y151-H10670938>
National Diet Library
  • Subject Headingara-C ara-CTP N4-Behenoyl-ara-C 白血病 濃度曲線下面積...

Ara-CとAsparaginase/Hydroxyurea相乗効果の生化学的機序

Ara-CとAsparaginase/Hydroxyurea相乗効果の生化学的機序
Paper図書
久保田, 優, 京都大学1987-1988<Y151-S62570422>
National Diet Library
  • Subject HeadingCytosine arabinoside (Ara-C) Ara-CTP Hydroxyurea l-Asparaginase Me...

Combination of guanine arabinoside and Bcl-2 inhibitor YC137 overcome the cytarabine resistance in HL-60 leukemia cell line.

Combination of guanine arabinoside and Bcl-2 inhibitor YC137 overcome the cytarabine resistance in HL-60 leukemia cell line.
Digital文書・図像類
Nishi, Rie, Yamauchi, Takahiro, Negoro, Eiju, Takemura, Haruyuki, Ueda, Takanori2013-04Cancer Science104 4p.502-507
Other Libraries in Japan
  • Subject Heading... triphosphate (ara-CTP) Bcl-2 leukemia
  • Note (General)... triphosphate (ara-CTP), an active me...... production of ara-CTP and the induct......r of decreased ara-CTP production and...... by augmenting ara-CTP production and......d in decreased ara-CTP production. HL......eby increasing ara-CTP production and...... by augmenting ara-CTP production and reversing refr...

Close correlation of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate, an intracellular active metabolite, to the therapeutic efficacy of N(4)-behenoyl-1-beta-D-arabinofuranosylcytosine therapy for acute myelogenous leukemia.

Close correlation of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate, an intracellular active metabolite, to the therapeutic efficacy of N(4)-behenoyl-1-beta-D-arabinofuranosylcytosine therapy for acute myelogenous leukemia.
Digital文書・図像類
Yamauchi, Takahiro, Kawai, Yasukazu, Goto, Nobuyuki, Kishi, Shinji, Imamura, Shin, Yoshida, Akira, Urasaki, Yoshimasa, Fukushima, Toshihiro, Iwasaki, Hiromichi, Tsutani, Hiroshi, Masada, Mikio, Ueda, TakanoriJapanese Cancer Association2001-09Japanese journal of cancer research : Gann92 9p.975-982
Other Libraries in Japan
  • Subject HeadingBHAC ara-C ara-CTP Clinical pharmacokinetics AUC
  • Note (General)...-triphosphate (ara-CTP), the intracel......ng methods for ara-CTP were insuffici...... evaluated the ara-CTP pharmacokineti......ction therapy. ara-CTP could be monit...... intracellular ara-CTP for a longer t......-time curve of ara-CTP was significan......ater amount of ara-CTP was attributed to the higher ara-CTP concentrations......irst time, the ara-CTP pharmacokineti...... importance of ara-CTP was proven. Ad......itoring of the ara-CTP pharmacokinetics in each indi...

Monitoring of intracellular 1-beta-D-arabinofuranosylcytosine 5'-triphosphate in 1-beta-D-arabinofuranosylcytosine therapy at low and conventional doses.

Monitoring of intracellular 1-beta-D-arabinofuranosylcytosine 5'-triphosphate in 1-beta-D-arabinofuranosylcytosine therapy at low and conventional doses.
Digital文書・図像類
Yamauchi, Takahiro, Kawai, Yasukazu, Kishi, Shinji, Goto, Nobuyuki, Urasaki, Yoshimasa, Imamura, Shin, Fukushima, Toshihiro, Yoshida, Akira, Iwasaki, Hiromichi, Tsutani, Hiroshi, Masada, Mikio, Ueda, TakanoriJapanese Cancer Association2001-05Japanese journal of cancer research : Gann92 5p.546-553
Other Libraries in Japan
  • Subject Headingara-C ara-CTP clinical pharmacokinetics low...
  • Note (General)...-triphosphate (ara-CTP). However, ara-CTP has seldom bee...... 1804 (1996)), ara-CTP was monitored ......(6 patients)]. Ara-CTP could be deter...... intracellular ara-CTP. The presence ......nt to maintain ara-CTP. The continuou......ons maintained ara-CTP and the plasma......atively higher ara-CTP concentrations......ently produced ara-CTP more efficient...... quantities of ara-CTP even at the same dose.

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