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Activated Factor X Signaling Pathway via Protease-Activated Receptor 2 is a Novel Therapeutic Target for Preventing Atrial Fibrillation 85 8

Activated Factor X Signaling Pathway via Protease-Activated Receptor 2 is a Novel Therapeutic Target for Preventing Atrial Fibrillation 85 8
Digital博士論文障害者向け資料あり
Matsuura, Tomomi, Soeki, Takeshi, Fukuda, Daiju, Uematsu, Etsuko, Tobiume, Takeshi, Hara, Tomoya, Kusunose, Kenya, Ise, Takayuki, Yamaguchi, Koji, Yagi, Shusuke, Yamada, Hirotsugu, Wakatsuki, Tetsuzo, Sata, MasatakaThe Japanese Circulation Society2021-07-21Circulation Journal
National Diet Library
  • Subject Headingatrial fibrillation FXa PAR2 inflammation anticoagula...
  • Note (General)...ated factor X (FXa), which contri......nclusions: The FXa–PAR2 signaling......tion. A direct FXa inhibitor, rivaroxaban, could...

Rivaroxaban, a specific FXa inhibitor, improved endothelium-dependent relaxation of aortic segments in diabetic mice 9

Rivaroxaban, a specific FXa inhibitor, improved endothelium-dependent relaxation of aortic segments in diabetic mice 9
Digital博士論文障害者向け資料あり
Pham, Tran Phuong, Fukuda, Daiju, Yagi, Shusuke, Kusunose, Kenya, Yamada, Hirotsugu, Soeki, Takeshi, Shimabukuro, Michio, Sata, MasatakaSpringer Nature2019-08-01Scientific Reports
National Diet Library
  • Subject HeadingRivaroxaban FXa PAR2 Endothelial dysfunction
  • Note (General)Activated factor X (FXa) plays a centr...... inhibition of FXa by rivaroxaban, a direct FXa inhibitor, att......ion of a major FXa receptor, PAR2...... PAR2−/− mice. FXa or a PAR2 agon...... PAR2−/− mice. FXa promoted JNK p......cells (HCAEC). FXa-induced endoth......s suggest that FXa or PAR2 is a potential therap...

Potential role of activated factor VIII (FVIIIa) in FVIIa/tissue factor-dependent FXa generation in initiation phase of blood coagulation. 109 4

Potential role of activated factor VIII (FVIIIa) in FVIIa/tissue factor-dependent FXa generation in initiation phase of blood coagulation. 109 4
Digital博士論文障害者向け資料あり
Furukawa, Shoko, Nogami, Keiji, Ogiwara, Kenichi, Shima, MidoriSpringer Nature2019-04International journal of hematology Vol. No. p. (2019 Apr)
National Diet Library
  • Subject HeadingFVIIa Tissue factor FVIII FXa generation Initiation phase
  • Note (General)...n by promoting FXa generation (ex......n of intrinsic FXa (intrinsic-Xa)......, and FVIIa/TF/FXa activates FVII......FVIII/FVIIa/TF/FXa relationships ......hanisms. Total FXa generated by F......(1 min); total FXa with FVIIa-inh.......7 nM, whereas FXa generated by F...... activation by FXa with FVIIa/TF ......ects of VWF on FXa-induced FVIII ......TF-induced and FXa-induced FVIII activation medi...

Rivaroxaban, a specific FXa inhibitor, improved endothelium-dependent relaxation of aortic segments in diabetic mice

Rivaroxaban, a specific FXa inhibitor, improved endothelium-dependent relaxation of aortic segments in diabetic mice
Digital博士論文
ファン, トラン フォン, 福田, 大受, 八木, 秀介, 楠瀬, 賢也, 山田, 博胤, 添木, 武, 島袋, 充生, 佐田, 政隆Springer Nature2019-08-01Scientific Reports9p.11206-
Available onlineOther Libraries in Japan
  • Summary, etc.Activated factor X (FXa) plays a centr...... inhibition of FXa by rivaroxaban, a direct FXa inhibitor, att......ion of a major FXa receptor, PAR2...... PAR2−/− mice. FXa or a PAR2 agon...... PAR2−/− mice. FXa promoted JNK p......cells (HCAEC). FXa-induced endoth......s suggest that FXa or PAR2 is a potential therap...
  • Subject HeadingRivaroxaban FXa PAR2 Endothelial dysfunction

Potential role of activated factor VIII (FVIIIa) in FVIIa/tissue factor-dependent FXa generation in initiation phase of blood coagulation.

Potential role of activated factor VIII (FVIIIa) in FVIIa/tissue factor-dependent FXa generation in initiation phase of blood coagulation.
Digital博士論文
Furukawa, Shoko, Nogami, Keiji, Ogiwara, Kenichi, Shima, MidoriSpringer Nature2019-04International journal of hematology Vol. No. p. (2019 Apr)109 4p.390-401
Available onlineOther Libraries in Japan
  • Subject HeadingFVIIa Tissue factor FVIII FXa generation Initiation phase
  • Note (General)...n by promoting FXa generation (ex......n of intrinsic FXa (intrinsic-Xa)......, and FVIIa/TF/FXa activates FVII......FVIII/FVIIa/TF/FXa relationships ......hanisms. Total FXa generated by F......(1 min); total FXa with FVIIa-inh.......7 nM, whereas FXa generated by F...... activation by FXa with FVIIa/TF ......ects of VWF on FXa-induced FVIII ......TF-induced and FXa-induced FVIII activation medi...

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