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            <description>&#x5f35;, &#x8d85;&#x7426;. &#x30ad;&#x30e1;&#x30e9;&#x578b;STAR&#x53d7;&#x5bb9;&#x4f53;&#x306f;&#x3001;&#x9ad8;&#x611f;&#x53d7;&#x6027;&#x3092;&#x6301;&#x3064;TCR&#x9670;&#x6027;CD8&#x3b1;&#x3b2; CD3&#x967d;&#x6027;&#x7d30;&#x80de;&#x306e;&#x30d2;&#x30c8;&#x4eba;&#x5de5;&#x591a;&#x80fd;&#x6027;&#x5e79;&#x7d30;&#x80de;&#x304b;&#x3089;&#x306e;&#x5206;&#x5316;&#x3092;&#x53ef;&#x80fd;&#x306b;&#x3059;&#x308b;. Kyoto University, 2026-03-23. DOI:10.14989/doctor.k26643</description>
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            <description>Marie-Paule Lefranc, G&#xe9;rard Lefranc. The T cell receptor factsbook. Academic Press, c2001. ISBN:0124413528</description>
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            <description>&#x4e2d;&#x5c3e;, &#x771e;&#x4e8c;; Nakao, Shinji. &#x518d;&#x751f;&#x4e0d;&#x826f;&#x6027;&#x8ca7;&#x8840;&#x60a3;&#x8005;&#x9aa8;&#x9ac4;&#x304b;&#x3089;&#x306e;&#x9020;&#x8840;&#x50b7;&#x5bb3;&#x6027;T&#x30ea;&#x30f3;&#x30d1;&#x7403;&#x30af;&#x30ed;&#x30fc;&#x30f3;&#x306e;&#x5358;&#x96e2;. 1997-03-03. DOI:10.24517/00066421</description>
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            <title>Regulation of memory CD4+ T cell generation by intrinsic and extrinsic IL-27 signaling during malaria infection / Tsogtsaikhan, Sanjaadorj</title>
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            <description>Tsogtsaikhan, Sanjaadorj. Regulation of memory CD4+ T cell generation by intrinsic and extrinsic IL-27 signaling during malaria infection. The Japanese Society for Immunology, 2024-09-04&lt;br&gt;The generation and maintenance of memory T cells are regulated by various factors, including cytokines. Previous studies have shown that IL-27 is produced during the early acute phase of Plasmodium chabaudi chabaudi AS (Pcc) infection and inhibits the development of Th1-type memory CD4+ T cells. However, whether IL-27 acts directly on its receptor on Plasmodium-specific CD4+ T cells or indirectly via its receptor on other immune cells remains unclear. We aimed to determine the role of IL-27 receptor signaling in different immune cell types in regulating the generation and phenotype of memory CD4+ T cells during Plasmodium infection. We utilized Plasmodium-specific T-cell antigen receptor (TCR) transgenic mice, PbT-II, and Il27r&#x3b1;&#x2212;/&#x2212; mice to assess the direct and indirect effects of IL-27 signaling on memory CD4+ T-cell generation. Mice were transferred with PbT-II or Il27r&#x3b1;&#x2212;/&#x2212; PbT-II cells and infected with Pcc. Conditional knockout mice lacking the IL-27 receptor in T cells or dendritic cells were employed to discern the specific immune cell types involved in IL-27 receptor signaling. High levels of memory in PbT-II cells with Th1-shift occurred only when both PbT-II and host cells lacked the IL-27 receptor, suggesting the predominant inhibitory role of IL-27 signaling in both cell types. Furthermore, IL-27 receptor signaling in T cells limited the number of memory CD4+ T cells, while signaling in both T and dendritic cells contributed to the Th1 dominance of memory CD4+ T cells. These findings underscore the complex cytokine signaling network regulating memory CD4+ T cells during Plasmodium infection.</description>
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            <description>&#x5185;&#x7530;, &#x53cb;&#x4e00;&#x6717;. RLTPR Q575E : &#x6210;&#x4eba;T&#x7d30;&#x80de;&#x767d;&#x8840;&#x75c5;/&#x30ea;&#x30f3;&#x30d1;&#x816b;&#x306b;&#x304a;&#x3051;&#x308b;&#x65b0;&#x898f;&#x53cd;&#x5fa9;&#x6027;&#x6a5f;&#x80fd;&#x7372;&#x5f97;&#x578b;&#x5909;&#x7570;. John Wiley &amp; Sons Ltd, 2021-02-25</description>
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            <pubDate>Sat, 04 Jul 2026 21:48:57 +0900</pubDate>
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            <link>https://ndlsearch.ndl.go.jp/books/R100000039-I8951762</link>
            <description>&#x962a;&#x672c;, &#x8cb4;&#x58eb;. CKIP-1&#x306f;&#x3001;CARMA1&#x3068;&#x306e;&#x76f8;&#x4e92;&#x4f5c;&#x7528;&#x3092;&#x4ecb;&#x3057;&#x3066;&#x3001;T&#x7d30;&#x80de;&#x6d3b;&#x6027;&#x5316;&#x3092;&#x6291;&#x5236;&#x7684;&#x306b;&#x5236;&#x5fa1;&#x3059;&#x308b;. Kyoto University, 2014-05-23. DOI:10.14989/doctor.k18463; 10.14989/doctor.k18463</description>
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            <pubDate>Sat, 07 Mar 2026 14:39:15 +0900</pubDate>
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