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Sex differences in left ventricular afterload and diastolic function are independent from the aortic size. / 反町, 秀美

Tue, 23 Jun 2026 16:35:25 +0900

反町, 秀美. Sex differences in left ventricular afterload and diastolic function are independent from the aortic size.. 群馬大学医学系研究科, 2019-06-30

A clinical application of preload stress echocardiography for predicting future hemodynamic worsening in patients with early-stage heart failure / 西條, 良仁ほか

Fri, 12 Jun 2026 12:24:10 +0900

Left Ventricular Diastolic Performance in Neonates / Iwashima, Satoru

Mon, 30 Oct 2023 19:56:15 +0900

Iwashima, Satoru. Left Ventricular Diastolic Performance in Neonates. 日本循環器学会, 2005-08-20

Sex differences in left ventricular afterload and diastolic function are independent from the aortic size. / 反町, 秀美

Wed, 06 Aug 2025 09:41:09 +0900

反町, 秀美. Sex differences in left ventricular afterload and diastolic function are independent from the aortic size.. 群馬大学医学系研究科, 2019-06-30

A clinical application of preload stress echocardiography for predicting future hemodynamic worsening in patients with early-stage heart failure 35 10 / 西條, 良仁ほか

Sat, 04 Jul 2026 21:43:46 +0900

西條, 良仁; 山田, 博胤; 楠瀬, 賢也; 坂東, 美佳; ニシオ, ススム; トリイ, ユウタ; ヒラタ, ユキナ; セノ, ヒロミツ; 松浦, 朋美; 伊勢, 孝之; 飛梅, 威; 山口, 浩司; 八木, 秀介; 添木, 武; 若槻, 哲三; 佐田, 政隆. A clinical application of preload stress echocardiography for predicting future hemodynamic worsening in patients with early-stage heart failure 35 10. Wiley Periodicals, 2018-07-13; 35 10
Aim: To improve the prognosis of patients with heart failure, risk stratification in their early stage is important. We assessed whether the change in transmitral flow (TMF) velocity pattern during preload augmentation can predict future hemodynamic worsening in early-stage heart failure patients with impaired relaxation TMF pattern.Methods: We designed a prospective cohort study that included 155 consecutive patients with impaired relaxation (IR) pattern at rest. Preload stress echocardiography was achieved using leg positive pressure (LPP), and changes of TMF pattern during the LPP was observed during baseline echocardiographic examination. The patients whose TMF pattern developed to pseudonormal (PN) pattern throughout the study period were classified into the change to PN group, and patients whose TMF pattern stayed in IR pattern were classified into the stay in IR group.Results: The median follow-up period was 17 months. The average age was 68 ± 11 years old, and 97 patients (63%) were male. Among 155 patients, 27 were classified into the change to PN group. A Cox proportional hazard analysis confirmed that the change in the peak atrial systolic TMF velocity during the LPP (ΔA, hazard ratio = 0.58 per 1SD; 95% CI = 0.39 - 0.88, P = 0.010) was the powerful independent predictor of change into PN pattern. Kaplan-Meier analysis revealed that the patients with ΔA ≤ -7 cm/s had more likely to develop into PN pattern than patients with ΔA > -7 cm/s (P = 0.001).Conclusions: Evaluation of a response in TMF during the LPP might provide an incremental diagnostic value to detect future overt heart failure in patients with early-stage heart failure.