Search results 12
Paper図書
National Diet Library
- Subject Headingara-C / DNA / 耐性 / microarray
Paper図書
National Diet Library
- Subject Headingara-C ara-CTP N4-Behenoyl-ara-C 白血病 濃度曲線下面積 TDM
Paper図書
National Diet Library
- Subject Heading抗がん剤耐性 / 白血病 / 定量PCR / 多剤耐性遺伝子 / (MDR) / ara-C
Digital博士論文障害者向け資料あり
National Diet Library
- Subject HeadingLentiviral barcoding Clonal analysis Subependymal zone Neurospheres Transit amplifying cell Ara-C
Paper図書
National Diet Library
- Subject Heading血中薬剤濃度自動シミユレーター 血中薬物動態 薬剤感受性試験 コロニーアツセイ法 ara-C ダウノルビシン
Paper図書
National Diet Library
- Subject HeadingCytosine arabinoside (Ara-C) Ara-CTP Hydroxyurea l-Asparaginase ...
Digital博士論文
Available onlineOther Libraries in Japan
- Subject HeadingLentiviral barcoding Clonal analysis Subependymal zone Neurospheres Transit amplifying cell Ara-C
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Other Libraries in Japan
- Subject Headingcytarabine (ara-C) 9-β-D-arabino...... triphosphate (ara-CTP) Bcl-2 leukemia
- Note (General)Cytarabine (ara-C) is the key ag......eukemic cells, ara-C is phosphoryla......nase (dCK), to ara-C triphosphate (ara-CTP), an active ......ytotoxicity of ara-C depends on the production of ara-CTP and the indu......ablished a new ara-C-resistant acut......ll line (HL-60/ara-C60) with dual r......r of decreased ara-CTP production a...... by augmenting ara-CTP production a......subclone HL-60/ara-C60 was 60-fold more ara-C-resistant than......0 cells. HL-60/ara-C60 cells exhibi......d in decreased ara-CTP production. HL-60/ara-C60 cells were a...... refractory to ara-C-induced apopto......n treatment of ara-C with ara-G augmented the dCK ...
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- Subject HeadingAra-C F-ara-A Drug resistance Leuke...
- Note (General)...of cytarabine (ara-C) with fludarab...... metabolite of ara-C, ara-C 5'-triphosphate (ara-CTP). Therapy-re......ia may exhibit ara-C resistance, th......t of combining ara-C and fludarabine on ara-C-resistant leuk......d 10-fold more ara-C resistant, res......ler amounts of ara-CTP. Both varian......nt followed by ara-C incubation pro......for augmenting ara-CTP production, ......reby enhancing ara-C cytotoxicity. ......phosphate over ara-C monophosphate,......otentiation of ara-C cytotoxicity i......enhancement of ara-C cytotoxicity d......ccumulation in ara-C-resistant leuk......e mechanism of ara-C resistance.
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- Subject Headingara-C DNA repair UV BCNU Comet assa...
- Note (General)...nosylcytosine (ara-C), an inhibitor......combination of ara-C with DNA damag......ir will expand ara-C cytotoxicity t......incubated with ara-C prior to irrad......th inhibited. ara-C-mediated inhib......ing at 10 μM. ara-C combined with ......he presence of ara-C. In conclusion, ara-C was cytotoxic ......alternatively, ara-C might exert its own cytotoxic...
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- Subject HeadingBHAC ara-C ara-CTP Clinical pharmacokinetics A...
- Note (General)...-triphosphate (ara-CTP), the intrac...... metabolite of ara-C derived from B......ng methods for ara-CTP were insuffi...... evaluated the ara-CTP pharmacokine......ction therapy. ara-CTP could be mon......vels of plasma ara-C and intracellular ara-CTP for a longer......s of high-dose ara-C. The area unde......-time curve of ara-CTP was signific......ater amount of ara-CTP was attribut...... to the higher ara-CTP concentratio......ence of plasma ara-C pharmacokineti......irst time, the ara-CTP pharmacokine...... importance of ara-CTP was proven. ......itoring of the ara-CTP pharmacokinetics in each in...
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- Subject Headingara-C ara-CTP clinical pharmacokinetics l...
- Note (General)...nosylcytosine (ara-C) is used empir...... or high dose. Ara-C therapy may be...... metabolite of ara-C, 1-beta-D-arab......-triphosphate (ara-CTP). However, ara-CTP has seldom b......ventional-dose ara-C therapies beca...... 1804 (1996)), ara-CTP was monitore......ventional-dose ara-C [subcutaneous ara-C administration......s), continuous ara-C infusion (20 o......patients), 2-h ara-C infusion (70 m......nase-resistant ara-C derivative (70......(6 patients)]. Ara-CTP could be det...... of the plasma ara-C and the intracellular ara-CTP. The presence of ara-C in the plasma ......nt to maintain ara-CTP. The continuous ara-C and t...