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白血病治療の分子標的としてのAML1複合体

白血病治療の分子標的としてのAML1複合体
Paper図書
北林一生, 国立がんセンター研究所 [著][北林一生]2003-2005<Y151-H15390033>
National Diet Library
  • Subject Heading白血病 / 染色体転座 / AML1 / HIPK2 / タンパク質リン酸化

Homeodomain interacting protein kinase 2 regulates DNA damage response through interacting with heterochromatin protein 1γ 34 26

Homeodomain interacting protein kinase 2 regulates DNA damage response through interacting with heterochromatin protein 1γ 34 26
Digital博士論文障害者向け資料あり
Akaike, Yoko, Kuwano, Yuki, Nishida, Kensei, Kurokawa, Ken, Kajita, Keisuke, Kano, Shizuka, Masuda, Kiyoshi, Rokutan, KazuhitoSpringer Nature2014-08-25Oncogene
National Diet Library
  • Subject HeadingDNA damage response HIPK2 HP1γ chromatin remodeling DNA...
  • Note (General)...tein kinase 2 (HIPK2) is a potentia......nclear whether HIPK2 exerts distinc......molecule(s) of HIPK2, which mediates HIPK2-dependent DNA damage repair. HIPK2-knockdown huma......T116) or hipk1/hipk2 double-deficie....... Knockdown of HIPK2 in p53-null HC......ic analysis of HIPK2-associated pro......vel target for HIPK2. Immunoprecipi......ng FLAG-tagged HIPK2 and one of the......onstrated that HIPK2 specifically a......SV-887) within HIPK2 abolished the ......ng activity of HIPK2. Sublethal UV-...... in endogenous HIPK2-silenced cells with HIPK2 3’UTR siRNA. O......ession of FLAG-HIPK2, but not the H......or kinase-dead HIPK2 mutant, in the HIPK2-silenced...
  • Alternative Title...vel target for HIPK2

Homeodomain interacting protein kinase 2 regulates DNA damage response through interacting with heterochromatin protein 1γ

Homeodomain interacting protein kinase 2 regulates DNA damage response through interacting with heterochromatin protein 1γ
Digital博士論文
赤池, 瑶子, 桑野, 由紀, 西田, 憲生, クロカワ, ケン, カジタ, ケイスケ, カノ, シズカ, 増田, 清士, 六反, 一仁Springer Nature2014-08-25Oncogene34 26p.3463-3473
Available onlineOther Libraries in Japan
  • Summary, etc....tein kinase 2 (HIPK2) is a potentia......nclear whether HIPK2 exerts distinc......molecule(s) of HIPK2, which mediates HIPK2-dependent DNA damage repair. HIPK2-knockdown huma......T116) or hipk1/hipk2 double-deficie....... Knockdown of HIPK2 in p53-null HC......ic analysis of HIPK2-associated pro......vel target for HIPK2. Immunoprecipi......ng FLAG-tagged HIPK2 and one of the......onstrated that HIPK2 specifically a......SV-887) within HIPK2 abolished the ......ng activity of HIPK2. Sublethal UV-...... in endogenous HIPK2-silenced cells with HIPK2 3’UTR siRNA. O......ession of FLAG-HIPK2, but not the H......or kinase-dead HIPK2 mutant, in the HIPK2-silenced...
  • Subject HeadingDNA damage response HIPK2 HP1γ chromatin remodeling DNA...
  • Alternative Title...vel target for HIPK2

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