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酵母機能診断系によるDNAミスマツチ修復遺伝子変異の機能マツピング

Paper図書

石岡, 千加史, 東北大学1999-2001<Y151-H11470503>

National Diet Library

Subject HeadingDNAミスマツチ修復 MLH1

遺伝子変異メチル化の定量的検出法の開発と子宮内膜癌発生予知への臨床応用

Paper図書

井上正樹, 金沢大学 [著][井上正樹]2001-2003<Y151-H13557137>

National Diet Library

Subject Heading子宮体癌 / 早期発見 / 分子標的 / テイラーメイド癌検診 / DNA修復遺伝子 / MLH1 / テロメラーゼ

MicroRNA-449a deficiency promotes colon carcinogenesis 7

Digital博士論文障害者向け資料あり

Niki, Masanori, Nakajima, Kohei, Ishikawa, Daichi, Nishida, Jun, Ishifune, Chieko, Tsukumo, Shin-ichi, Shimada, Mitsuo, Nagahiro, Shinji, Mitamura, Yoshinori, Yasutomo, KojiSpringer Nature2017-09-06Scientific Reports

National Diet Library

Subject HeadingmicroRNA-449a colon carcinogenesis Notch signaling MlH1
Note (General)... expression of MLH1 for which loss......showed reduced Mlh1 expression compared with thos...

MLH1-mediated recruitment of FAN1 to chromatin for the induction of apoptosis triggered by O6-methylguanine

Digital博士論文障害者向け資料あり

Rikitake, Mihoko, Fujikane, Ryosuke, Obayashi, Yuko, Oka, Kyoko, Ozaki, Masao, Hidaka, Masumi2020-03-14

National Diet Library

Subject Headingapoptosis FANCD2 and FANCI-associated nuclease 1 (FAN1) O6-methylguanine mismatch repair (MMR) MLH1
Note (General)...ing partner of MLH1. Immunoprecipi......cted with both MLH1 and MSH2 after......ear foci in an MLH1-dependent mann......ized with both MLH1 foci and singl......teraction with MLH1 and produces ssDNA by its exo...
Alternative TitleMLH1-mediated recruitment of FAN1 ...

MicroRNA-449a deficiency promotes colon carcinogenesis

Digital博士論文

仁木, 昌徳, 中島, 公平, 石川, 大地, 西田, 純, 石舟, 智恵子, 九十九, 伸一, 島田, 光生, 永廣, 信治, 三田村, 佳典, 安友, 康二Springer Nature2017-09-06Scientific Reports7p.10696-

Available onlineOther Libraries in Japan

Summary, etc.... expression of MLH1 for which loss......showed reduced Mlh1 expression compared with thos...
Subject HeadingmicroRNA-449a colon carcinogenesis Notch signaling MlH1

線虫 Caenorhabditis elegans を用いたストレス応答機構に関する研究

Digital博士論文

森脇, 隆仁京都大学 (Kyoto University)2014-03-24

Available onlineOther Libraries in Japan

Subject HeadingC. elegans DNA damage response DNA mismatch repair Aging Drug resistance ATM MLH1

遺伝子変異メチル化の定量的検出法の開発と子宮内膜癌発生予知への臨床応用

Digital文書・図像類

井上, 正樹, Inoue, Masaki2005-04-18平成15(2003)年度科学研究費補助金基盤研究(B) 研究成果報告書概要 = 2003 Fiscal Year Final Research Report Summary2001-2003p.2p.-

Other Libraries in Japan

Subject Heading...イド癌検診 DNA修復遺伝子 MLH1 テロメラーゼ DNA mis......ir genes human MLH1 hypermethylation of promoter ...
Note (General)...修復遺伝子の機能障害は体癌ではMLH1の発現異常が重要で、MLH1蛋白発現の低下は遺伝子の変異で......nce法を用いた。これによるとMLH1の蛋白発現はプロモーターのCp......同じ程度にメチル化がみられた。MLH1の過剰メチル化症例ではMSI及......れ,内膜の形態変化よりも早期にMLH1プロモーターのメチル化が進行す......lencing of the MLH1 gene by promot......bp upstream of MLH1 covering 48 Cp......d. Analysis of MLH1 by immunohisto...... for decreased MLH1 expression and......ylation of the MLH1 promoter is frequent in the h...
Alternative Title...nethylation of MLH1 promoter and its clinical app...

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