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- Contents...eases: repurposing knowledge, mechanisms and therapeutics to increase discover......y / David C. Swinney, Michael P....... of zika virus infection: lesson......aul C. Jordan, Andreas Jekle, Jer......e Deval Developing therapeutics ......rickson, Christina F Spiropoulou Part II. Kinetoplastids. Designing drugs to targ...... disease: when chemistry needs biology / Martine Keenan, Eric Chatelain Drug discovery and development fo......panosomiasis / Andrew Spaulding, Mitchell F. Gallerstein, Lori Ferrins Discovery of ......s report / Baljinder Singh, Frederick S...... Part III. Helminths. Onchocerci......wryluk, Ivan Scandale Drug discovery and develop...
- Subject HeadingTropical medicine. Drug development. Tropical Medicine. Drug Development.
- Title HeadingMethods and principles in medicinal chemistry ; v. 77.
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- Subject HeadingProtein drugs. Proteins--Therapeutic use.
- Related MaterialMethods and principles in medicinal chemistry
- Periodical TitleMethods and principles in medicinal chemistry
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National Diet Library
- Summary, etc....rs key aspects in early drug dev......iscovery phase and are required for first-in-human studies....... broad scope brings together cri......om many disciplines, ranging from process ......harmacology to intellectual prop...... issues. After introducing the overall e...... are described in a sequential and enabling order: the av......drug substance and that of the dr......on of pharmacokinetics and -dynamics, as ......g safety. The final section focuses on intellectual prop......rty aspects during early clinical developmen......lify salient points, resulting in an abundance o......ctice-oriented information that is usually not ...
- Subject HeadingDrug development. Drugs--Testing. Clinical trials. Human experimentation in medicine.
- Title HeadingMethods and principles in medicinal chemistry ; v. 73.
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- Subject HeadingBiological Products--chemistry. Biological Pr......Pharmaceutical chemistry. Naturstoff Pharmazeutische C...
- Title HeadingMethods and principles in medicinal chemistry ; v. 60.
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- ContentsPt. 1. Principles pt. 2. Data pt. 3. Methods pt. 4. Applications.
- Subject HeadingPharmaceutical chemistry.
- Author HeadingBrown, Nathan (Medicinal chemist)
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- Subject HeadingCombinatorial Chemistry Techniques. Microwaves. Chemistry, Organic. Chemistry, Pharmaceutica......Pharmaceutical chemistry. Organic compounds--Synthesis...
- Title HeadingMethods and principles in medicinal chemistry ; v. 52.
- Author HeadingKappe, C. Oliver. Stadler, Alexander, 1973- Dallinger, Doris.
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- Subject Heading...sign. Pharmacokinetics. Drugs--Metabolism. Drug...
- Title HeadingMethods and principles in medicinal chemistry ; v. 51.
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- ContentsIn vitro characte......mall-molecule kinase inhibitors Screening for kinase inhibitors: from ...... assays Dissecting phosphorylati......gue-sensitive kinases and more specific kinase inhibitors as too......rug design of kinase inhibitors for si......ction therapy Kinaes inhibitors in signal transdu......therapy Design principles of deep pocket-targeting protein kinase inhibitors From discovery to clinic: aurora kinase inhibitors as nov......ncer Discovery and design of protein kinase inhibitors: targeting the cell cycle in oncology Medicinal chemistry approaches for the inhibition of the...... Cellular protein kinases as antiviral targets ...
- Subject HeadingProtein Kinase Inhibitors -- the......iscovery. Protein kinases -- Inhibitors. Antineoplastic agents -- Developmen...
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- Contentsv. 1. Alphabetical listing v. 2. Appendices, references...
- Subject HeadingDrugs -- Design. Cheminformatics. Drug Design -- Handbooks. Models, Molecular -- Handbooks. Molecula......nformation -- Handbooks. Pharmacology, Clinical -- Handbooks. Molecular pharmacology.
- Note (General)Updated ed. of: Handbook of molecular descriptors,...
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- Note (General)...r biographical information http: //www.loc.gov/...
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- Subject Heading...Diseases, Emerging--drug therapy
- Title HeadingMethods and principles in medicinal chemistry ; v. 80
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National Diet Library
- ContentsNatural products in drug discovery......ern approaches in the search for......lead compounds in medicinal chemistry / Eliezer J. B......los A.M. Fraga and Lidia M. Lima ......ural compounds in drug discovery and development / ......tion of plants and their constitu......tural products in discovery of new anti-infective agents ......aximiliano Sortino ... [et al.] ......s / Luiz C. Klein-Junior, José R. Santin and Sérgio F. de Andrade Recent progress in the chemistry and biology of pac......itaxel (Taxol) and related taxane......Qi, Jielu Zhao and David G.I. Kingston Cancer ch...... / A. Douglas Kinghorn ... [et al.] Medicinal p...
- Subject Heading...Pharmaceutical chemistry. Plants, Medicinal--metabolism. Drug Discovery. ...
- Title HeadingWiley series in drug discovery and development.
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National Diet Library
- ContentsFront Matter Introduction. His......e / ROBERTA S KING Factors Affecting Metabolism / ROBERTA S KING Biotransformations in Drug Metabolism / ROBERTA S KING A Comprehensi......transformation in Drug Discovery......ATI, YANG YUAN In Vivo Drug Metabolite Kinetics / ZHENG Y......sed Proteomics Methods for Quantifying Drug-Metabolizing Enzymes and Transporters /...... S Smith, SUN MIN JUNG, JIAPENG ......chnologies for In vitro and In vivo Studies. ......SHARP Accelerating Metabolite Id......tions of Drug Candidates to Enhan......tions of Drug Candidates to Impro......ructural Alert and Reactive Metab......ept as Applied in Medicinal Chemistry to Minimi...
- Subject HeadingDrugs--Metabolism--Handbooks, manuals, etc Drugs--Met...
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National Diet Library
- ContentsVolume 1. General principles of supramolecular chemistry and molecular reco....... Experimental and computational methods in supramolecular chemistry / volume edito......n Volume 4. Bioinspired and biomimetic supramolecular chemistry / volume edito......wickramarajah, Andrew J. Wilson V......Supramolecular medicinal chemistry and chemical biolo......olume editors, Andrew J. Wilson, ......ramolecular engineering : discrete mo......ramolecular engineering : designing the solid sta......escent sensors and imaging agents / volu......ume editor, Colin Raston.
- Subject HeadingSupramolecular chemistry. SCIENCE / Chemistry / Physical & Theoretical
- Alternative TitleComprehensive supramolecular chemistry 2
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National Diet LibraryOther Libraries in Japan
- Contents...ives Synthesis and Applications: ......ate-of-the-Art and Perspectives 1.1 Introduction 1.2 ......ide: Synthesis Methods and Chemistry Alteration 1.3......xide Reduction and Functionalizat......MGs 1.5 Concluding Remarks Ackno......ionuclides 2.1 Introduction 2.2 ......Anionic SeO42− and Cationic Sr2+ ......plications 3.1 Introduction 3.1.1 Photothermal and Photodynamic T......y 3.1.2 Bioimaging and Drug/Gene Deli.......1.5 Tissue Engineering and Regenerative Medicine 3.2 Conclusio......odetectors 4.1 Introduction 4.2 ......Mechanism Enabling Photodetectio......ciency 4.4.4 Gain 4.4.5 Response...... 4.5 Synthesis Methods for 2D Materials 4.5.1 Mechan...
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- Subject Heading...Pharmaceutical chemistry Drugs -- Desig......cal Factors -- chemistry Biological Fac......ular Structure Chemistry, Pharmaceutica......Pharmaceutical chemistry fast
- Subject Heading (ID)...Pharmaceutical chemistry Drugs -- Desig......cal Factors -- chemistry Biological Fac......ular Structure Chemistry, Pharmaceutica......Pharmaceutical chemistry fast
- Note (General)Includes bibliographical references and index
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- Subject HeadingPharmaceutical chemistry
- Subject Heading (ID)Pharmaceutical chemistry
- Note (General)Includes bibliographical references and index
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- Subject HeadingPharmaceutical chemistry Microwaves Org......s -- Synthesis Chemistry, Pharmaceutica......Pharmaceutical chemistry fast
- Subject Heading (ID)Pharmaceutical chemistry Microwaves Org......s -- Synthesis Chemistry, Pharmaceutica......Pharmaceutical chemistry fast
- Note (General)Previous ed.: 2005 Formerly CIP Uk Includes bibliographical references and index
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- Subject HeadingMass spectrometry Pharmaceutical chemistry Drug development
- Subject Heading (ID)Mass spectrometry Pharmaceutical chemistry Drug development
- Note (General)Includes bibliographical references and index