偽悪性変化を伴った下顎歯肉腫瘤の1例
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- 資料種別
- 記事
- 著者・編者
- 吉岡 幸男小川 郁子林堂 安貴 他
- 並列タイトル等
- A case of lower gingival polypoid mass with pseudomalignant change
- タイトル（掲載誌）
- 日本口腔科学会雑誌
- 巻号年月日等（掲載誌）
- 59(2) 2010.3
- 掲載巻
- 59
- 掲載号
- 2
- 掲載ページ
- 63～67
- 掲載年月日（W3CDTF）
- 2010-03
- ISSN（掲載誌）
- 0029-0297
- ISSN-L（掲載誌）
- 0029-0297
- 出版事項（掲載誌）
- 東京 : 日本口腔科学会
- 出版地（国名コード）
- JP
- 本文の言語コード
- jpn
- NDLC
- 対象利用者
- 一般
- 所蔵機関
- 国立国会図書館
- 請求記号
- Z19-215
- 連携機関・データベース
- 国立国会図書館 : 国立国会図書館雑誌記事索引
- 書誌ID（NDLBibID）
- 10694866
- 整理区分コード
- 632
- 要約等
- We reported a case of pseudomalignant polypoid mass arising at the mandible, both clinically and histopathologically.<br>A 65-year-old man visited our hospital because of a mass at the left mandible. Oral examination revealed a polypoid mass at the molar region of the left mandible, which was elastic, soft and covered with normal mucosa. We diagnosed a reactive mass due to the marginal periodontitis of 78, so we planned to extract these teeth and extirpate the mass. A week later, the polypoid mass grew rapidly with an ulcer formation, and a biopsy was performed. The specimen comprised inflammatory granulation tissue with an ulcer, which contained scattered large bizarre spindle or stellate cells with enlarged and hyperchromatic nuclei. Moreover, mitotic figures and nuclear pleomorphism were occasionally observed in the overlaying mucosa. Immunohistochemical examination showed that the large cells expressed vimentin, and were negative for cytokeratins (CAM5.2, AE1/AE3) and p63. These finding suggested a benign inflammatory lesion as well as malignant lesions such as spindle cell carcinoma and sarcoma. <br>The patient underwent the biopsy again at the deep site near the alveolar bone when simultaneously being taken off the metal prosthesis (5678). The secondary biopsy specimen showed only proliferation of the granulation tissues without the large bizarre cells. The polypoid mass reduced in size and its surface became smooth a week after removing the prosthesis. Finally, we diagnosed that the polypoid mass was inflammatory gingival hyperplasia with pseudomalignant change. It was excised in association with the extraction of the lower left second and third molars. No sign of recurrence was noted three months after the treatment.
- DOI
- 10.11277/stomatology.59.63
- オンライン閲覧公開範囲
- インターネット公開
- 連携機関・データベース
- 科学技術振興機構 : J-STAGE
- 要約等
- We reported a case of pseudomalignant polypoid mass arising at the mandible, both clinically and histopathologically.<br>A 65-year-old man visited our hospital because of a mass at the left mandible. Oral examination revealed a polypoid mass at the molar region of the left mandible, which was elastic, soft and covered with normal mucosa. We diagnosed a reactive mass due to the marginal periodontitis of 78, so we planned to extract these teeth and extirpate the mass. A week later, the polypoid mass grew rapidly with an ulcer formation, and a biopsy was performed. The specimen comprised inflammatory granulation tissue with an ulcer, which contained scattered large bizarre spindle or stellate cells with enlarged and hyperchromatic nuclei. Moreover, mitotic figures and nuclear pleomorphism were occasionally observed in the overlaying mucosa. Immunohistochemical examination showed that the large cells expressed vimentin, and were negative for cytokeratins (CAM5.2, AE1/AE3) and p63. These finding suggested a benign inflammatory lesion as well as malignant lesions such as spindle cell carcinoma and sarcoma. <br>The patient underwent the biopsy again at the deep site near the alveolar bone when simultaneously being taken off the metal prosthesis (5678). The secondary biopsy specimen showed only proliferation of the granulation tissues without the large bizarre cells. The polypoid mass reduced in size and its surface became smooth a week after removing the prosthesis. Finally, we diagnosed that the polypoid mass was inflammatory gingival hyperplasia with pseudomalignant change. It was excised in association with the extraction of the lower left second and third molars. No sign of recurrence was noted three months after the treatment.
- DOI
- 10.11277/stomatology.59.63
- 関連情報（URI）
- 連携機関・データベース
- 国立情報学研究所 : CiNii Research
- 提供元機関・データベース
- Japan Link Center雑誌記事索引データベースCiNii ArticlesCiNii Articles科学研究費助成事業データベース科学研究費助成事業データベース科学研究費助成事業データベース
- 書誌ID（NDLBibID）
- 10694866
- NII論文ID
- 10027093100130004555748