Mycoplasma pulmonis接種によるマウスの肺炎 肺病変の形成と菌および抗体の推移〔英文〕
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- 資料種別
- 記事
- 著者・編者
- 跡部 ヒサエ 他
- 著者標目
- タイトル（掲載誌）
- 日本獣医学雑誌
- 巻号年月日等（掲載誌）
- 36(6) 1974.12
- 掲載巻
- 36
- 掲載号
- 6
- 掲載ページ
- 495～503
- 掲載年月日（W3CDTF）
- 1974-12
- ISSN（掲載誌）
- 0021-5295
- ISSN-L（掲載誌）
- 0021-5295
- 出版事項（掲載誌）
- 東京 : 日本獣医学会
- 出版地（国名コード）
- JP
- 本文の言語コード
- jpn
- NDLC
- 対象利用者
- 一般
- 所蔵機関
- 国立国会図書館
- 請求記号
- Z18-350
- 連携機関・データベース
- 国立国会図書館 : 国立国会図書館雑誌記事索引
- 書誌ID（NDLBibID）
- 7616331
- 整理区分コード
- 632
- 要約等
- Specific pathogen-free (SPF) ICR mice were inoculated intranasally with Mycoplasma pulmonis strain m53 and were observed during one-year period for the formation of pulmonary lesions, persistence of mycoplasmas and production of antibodies. Of the nasal cavity, the isolation rate was 100% during 3 months following inoculation, decreasing thereafter. While the organisms persisted for a longer period in the trachea than in any other sites of the respiratory tract, they were isolated only at a lower rate from the lung. Gross pulmonary lesions were first observed on the 2nd day after inoculation and, in earlier stage of infection, the incidence of pneumonic lesions correlated with mycoplasmal isolation rate, becoming a maximum 90% on the 20th day. Later, however, such correlation was not observed, although the incidence of lung lesions remained at 50% for 10 months. While the CF antibody was detected already 5 to 10 days after inoculation turning to negative in 90% of inoculated animals one year later, the IHA antibody was detected 20 or more days after inoculation persisting at high titers for one year or over. The MI antibody was first detectcd 2 months after inoculation at titers much lower than those in CF and IHA. In non-inoculated mice having been kept for 10 weeks as cage mates with inoculated ones, were found to have mycoplasmas and antibodies without no gross lesions in the lung.
- DOI
- 10.1292/jvms1939.36.495
- オンライン閲覧公開範囲
- インターネット公開
- 連携機関・データベース
- 科学技術振興機構 : J-STAGE
- 要約等
- Specific pathogen-free (SPF) ICR mice were inoculated intranasally with Mycoplasma pulmonis strain m53 and were observed during one-year period for the formation of pulmonary lesions, persistence of mycoplasmas and production of antibodies. Of the nasal cavity, the isolation rate was 100% during 3 months following inoculation, decreasing thereafter. While the organisms persisted for a longer period in the trachea than in any other sites of the respiratory tract, they were isolated only at a lower rate from the lung. Gross pulmonary lesions were first observed on the 2nd day after inoculation and, in earlier stage of infection, the incidence of pneumonic lesions correlated with mycoplasmal isolation rate, becoming a maximum 90% on the 20th day. Later, however, such correlation was not observed, although the incidence of lung lesions remained at 50% for 10 months. While the CF antibody was detected already 5 to 10 days after inoculation turning to negative in 90% of inoculated animals one year later, the IHA antibody was detected 20 or more days after inoculation persisting at high titers for one year or over. The MI antibody was first detectcd 2 months after inoculation at titers much lower than those in CF and IHA. In non-inoculated mice having been kept for 10 weeks as cage mates with inoculated ones, were found to have mycoplasmas and antibodies without no gross lesions in the lung.
- DOI
- 10.1292/jvms1939.36.495
- 関連情報（URI）
- 連携機関・データベース
- 国立情報学研究所 : CiNii Research
- 提供元機関・データベース
- Japan Link Center学術機関リポジトリデータベース雑誌記事索引データベースCrossrefPubMedCiNii Articles
- 書誌ID（NDLBibID）
- 7616331
- NII論文ID
- 110003919241