Aminosidineの眼科的応用(アミノサイジン Aminosidine(論文特集))

• 資料種別: 記事
• タイトル: Aminosidineの眼科的応用
• 著者・編者: 三国 政吉 他
• シリーズタイトル: アミノサイジン Aminosidine(論文特集)
• 著者標目: 三国 政吉
• タイトル（掲載誌）: Chemotherapy
• 巻号年月日等（掲載誌）: 16(2) 1968.02
• 掲載巻: 16
• 掲載号: 2
• 掲載ページ: 305～310
• 掲載年月日（W3CDTF）: 1968-02
• ISSN（掲載誌）: 0009-3165
• ISSN-L（掲載誌）: 0009-3165
• 出版事項（掲載誌）: 東京 : 日本化学療法学会
• 出版地（国名コード）: JP
• 本文の言語コード: jpn
• NDLC: ZS47
• 対象利用者: 一般
• コレクション（共通）: 障害者向け資料
• コレクション（障害者向け資料：レベル1）: テキストデータ
• コレクション（障害者向け資料：レベル2）: プレーンテキスト
• コレクション（個別）: 国立国会図書館デジタルコレクション > デジタル化資料 > 雑誌; https://dl.ndl.go.jp/collections/A00002
• オンライン閲覧公開範囲: 国立国会図書館内限定公開
• デジタル化資料送信: 図書館・個人送信対象外
• 遠隔複写可否（NDL）: 可
• 所蔵機関: 国立国会図書館
• 請求記号: Z19-42
• 掲載誌（国立国会図書館永続的識別子）: info:ndljp/pid/1800161; https://dl.ndl.go.jp/pid/1800161
• 連携機関・データベース: 国立国会図書館 : 国立国会図書館雑誌記事索引; https://ndlsearch.ndl.go.jp
• 書誌ID（NDLBibID）: 8097464; http://id.ndl.go.jp/bib/8097464
• 整理区分コード: 632

• 要約等: Bacterial and clinical experiments for ophth almic use of aminosidine (AMD) were performed, and the results summarized as follows.<BR>1) Minimum growth in hibitory concentration of AMD was 0. 07 mcg/ml for <I>K-W bacillus, </I> 0. 18∼0. 35 mcg/ml for <I>M-A bacillus, </I> 3. 55∼35. 5 mcg/ml for <I>Pneumococcus, </I>0. 35 mcg/ml for <I>C. diphtheriae, </I> 0. 35 m cg/ml for<I> Gonococcus, </I>35. 5 mcg/ml for <I>Streptococcus, </I>0. 18∼0. 71 mcg/ml for <I>Staphylococcus</I> and 35. 5∼71 mcgiml for <I>Pyocyaneus.</I><BR>2) The distribution of the sensitivity for 42 strains of <I>Staph. aureus</I> isolated in 1966 was in the range of ≤0. 07- ≥71 mcg/ml, and majority of them (92. 9) were in <3. 55 mcg/ml.<BR>3) The concentration in the blood by intramuscular injection of a single dose 0. 35 g reached the highest after 1 hour and decreased gradually until 12 hours.<BR>4) After instillation of 1% AMD eye-drops, the con centration was found in the tissue of the outer parts of the rabbit eye. After 15 mg subconjunctival injection, the concentration was obtained not only in the tissue of the outer segment, but also in the inner parts of the eye. After the intramuscular injection of AMD in a dose of 35. 5 mg/kg, the concentration was recognized in the outer and inner parts of the eye.<BR>5) Intram uscular injection of 0. 35 g AMD 1 or 2 times daily revealled excellent effects on 12 cases of hordeolum caused by <I>Staphylococcus, </I>4 cases of lid abscess, I case of dacryocystitis and corneal ulcer by <I>Pneumococcus, </I> and 2 cases of preventive application against post-removal of foreign body on the cornea.<BR>6) Side effects: Some of patients experienced slight pain on injection, but any other severe side effects were not noticed.
• DOI: 10.11250/chemotherapy1953.16.305
• オンライン閲覧公開範囲: インターネット公開
• 連携機関・データベース: 科学技術振興機構 : J-STAGE; http://www.jstage.jst.go.jp

• 要約等: Bacterial and clinical experiments for ophth almic use of aminosidine (AMD) were performed, and the results summarized as follows.<BR>1) Minimum growth in hibitory concentration of AMD was 0. 07 mcg/ml for <I>K-W bacillus, </I> 0. 18∼0. 35 mcg/ml for <I>M-A bacillus, </I> 3. 55∼35. 5 mcg/ml for <I>Pneumococcus, </I>0. 35 mcg/ml for <I>C. diphtheriae, </I> 0. 35 m cg/ml for<I> Gonococcus, </I>35. 5 mcg/ml for <I>Streptococcus, </I>0. 18∼0. 71 mcg/ml for <I>Staphylococcus</I> and 35. 5∼71 mcgiml for <I>Pyocyaneus.</I><BR>2) The distribution of the sensitivity for 42 strains of <I>Staph. aureus</I> isolated in 1966 was in the range of ≤0. 07- ≥71 mcg/ml, and majority of them (92. 9) were in <3. 55 mcg/ml.<BR>3) The concentration in the blood by intramuscular injection of a single dose 0. 35 g reached the highest after 1 hour and decreased gradually until 12 hours.<BR>4) After instillation of 1% AMD eye-drops, the con centration was found in the tissue of the outer parts of the rabbit eye. After 15 mg subconjunctival injection, the concentration was obtained not only in the tissue of the outer segment, but also in the inner parts of the eye. After the intramuscular injection of AMD in a dose of 35. 5 mg/kg, the concentration was recognized in the outer and inner parts of the eye.<BR>5) Intram uscular injection of 0. 35 g AMD 1 or 2 times daily revealled excellent effects on 12 cases of hordeolum caused by <I>Staphylococcus, </I>4 cases of lid abscess, I case of dacryocystitis and corneal ulcer by <I>Pneumococcus, </I> and 2 cases of preventive application against post-removal of foreign body on the cornea.<BR>6) Side effects: Some of patients experienced slight pain on injection, but any other severe side effects were not noticed.
• DOI: 10.11250/chemotherapy1953.16.305; https://doi.org/10.11250/chemotherapy1953.16.305
• 関連情報（URI）: http://id.ndl.go.jp/bib/8097464; https://ndlsearch.ndl.go.jp/books/R000000004-I8097464; https://search.jamas.or.jp/link/ui/1971101766
• 連携機関・データベース: 国立情報学研究所 : CiNii Research; https://cir.nii.ac.jp/
• 提供元機関・データベース: Japan Link Center; https://japanlinkcenter.org/top; 雑誌記事索引データベース; https://ndlsearch.ndl.go.jp; CiNii Articles
• 書誌ID（NDLBibID）: 8097464; http://id.ndl.go.jp/bib/8097464
• NII論文ID: 130004190678