H2A.Z Functions To Regulate Progression through the Cell Cycle

• 資料種別: 文書・図像類
• タイトル: H2A.Z Functions To Regulate Progression through the Cell Cycle
• 著者・編者: DHILLON, Namrita; OKI, Masaya; SZYJKA, SHAWN J.; APARICIO, Oscar M.; KAMAKAKA, Rohinton T.
• 著者標目: DHILLON, Namrita; OKI, Masaya; SZYJKA, SHAWN J.; APARICIO, Oscar M.; KAMAKAKA, Rohinton T.
• 出版事項: American Society for Microbiology
• 出版年月日等: 2006-01
• 出版年（W3CDTF）: 2006-01
• タイトル（掲載誌）: Molecular and Cellular Biology
• 巻号年月日等（掲載誌）: 26 2
• 掲載巻: 26
• 掲載号: 2
• 掲載ページ: 489-501
• 本文の言語コード: eng
• 対象利用者: 一般
• 一般注記: Histone H2A variants are highly conserved proteins found ubiquitously in nature and thought to perform specialized functions in the cell. Studies in yeast on the histone H2A variant H2A.Z have shown a role for this protein in transcription as well as chromosome segregation. Our studies have focused on understanding the role of H2A.Z during cell cycle progression. We found that htz1Δ cells were delayed in DNA replication and progression through the cell cycle. Furthermore, cells lacking H2A.Z required the S-phase checkpoint pathway for survival. We also found that H2A.Z localized to the promoters of cyclin genes, and cells lacking H2A.Z were delayed in the induction of these cyclin genes. Several different models are proposed to explain these observations.
• 一次資料へのリンクURL: https://u-fukui.repo.nii.ac.jp/?action=repository_action_common_download&item_id=22582&item_no=1&attribute_id=22&file_no=1
• オンライン閲覧公開範囲: 限定公開
• 連携機関・データベース: 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• 提供元機関・データベース: 福井大学 : 福井大学学術機関リポジトリ