Correlation and Characteristics of Intravoxel Incoherent Motion and Arterial Spin Labeling Techniques Versus Multiple Parameters Obtained on Dynamic Susceptibility Contrast Perfusion MRI for Brain Tumors

• 資料種別: 博士論文
• タイトル: Correlation and Characteristics of Intravoxel Incoherent Motion and Arterial Spin Labeling Techniques Versus Multiple Parameters Obtained on Dynamic Susceptibility Contrast Perfusion MRI for Brain Tumors
• 著者・編者: Dolgorsuren, Enkh-Amgalan; Harada, Masafumi; Kanazawa, Yuki; Abe, Takashi; Otomo, Maki; Matsumoto, Yuki; Mizobuchi, Yoshifumi; Nakajima, Kohhei
• 著者標目: Dolgorsuren, Enkh-Amgalan; Harada, Masafumi; Kanazawa, Yuki; Abe, Takashi; Otomo, Maki; Matsumoto, Yuki; Mizobuchi, Yoshifumi; Nakajima, Kohhei
• 出版事項: Tokushima University Faculty of Medicine
• 出版年月日等: 2019-08
• 出版年（W3CDTF）: 2019-08
• 並列タイトル等: 脳腫瘍におけるダイナミック磁化率コントラスト灌流MRIの各種パラメーターに対するintravoxel incoherent motion法とarterial spin labeling法との相関と特徴; Perfusion MRI for brain tumors
• タイトル（掲載誌）: The Journal of Medical Investigation
• 巻号年月日等（掲載誌）: 66 3-4
• 掲載巻: 66
• 掲載号: 3-4
• 掲載ページ: 308-313
• ISSN（掲載誌）: ISSN : 1349-6867; ISSN : 1343-1420
• 授与機関名: 徳島大学
• 授与年月日: 2019-09-26
• 報告番号: 甲第3336号
• 学位: 博士（医学）
• 本文の言語コード: eng
• 件名標目: Intravoxel incoherent motion; brain tumor; arterial spin labeling; dynamic susceptibility contrast perfusion
• 対象利用者: 一般
• 一般注記: Purpose : To compare data on brain tumors derived from intravoxel incoherent motion (IVIM) and arterial spin labeling (ASL) imaging with multiple parameters obtained on dynamic susceptibility contrast (DSC) perfusion MRI and to clarify the characteristics of IVIM and ASL perfusion data from the viewpoint of cerebral blood flow (CBF) analysis. Methods : ASL-CBF and IVIM techniques as well as DSC examination were performed in 24 patients with brain tumors. The IVIM data were analyzed with the two models. The relative blood flow (rBF), relative blood volume (rBV) corrected relative blood volume (crBV), mean transit time (MTT), and leakage coefficient (K2) were obtained from the DSC MRI data. Results : The ASL-CBF had the same tendency as the perfusion parameters derived from the DSC data, but the permeability from the vessels had less of an effect on the ASL-CBF. The diffusion coefficient of the fast component on IVIM contained more information on permeability than the f value. Conclusion : ASL-CBF is more suitable for the evaluation of perfusion in brain tumors than IVIM parameters. ASL-CBF and IVIM techniques should be carefully selected and the biological significance of each parameter should be understood for the correct comprehension of the pathological status of brain tumors.
• 記録形式（IMT）: application/pdf
• 一次資料へのリンクURL: fulltext; http://repo.lib.tokushima-u.ac.jp/files/public/11/113793/20191011150446839389/k3336_abstract_review.pdf; http://repo.lib.tokushima-u.ac.jp/files/public/11/113793/20191016115948746619/k3336_fulltext.pdf
• オンライン閲覧公開範囲: インターネット公開
• 関連情報（DOI）: 10.2152/jmi.66.308
• 掲載誌（NCID）: AA12022913; https://ci.nii.ac.jp/ncid/AA12022913; AA11166929; https://ci.nii.ac.jp/ncid/AA11166929
• 連携機関・データベース: 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• 提供元機関・データベース: 徳島大学 : 徳島大学機関リポジトリ