Phosphatemic index is a novel evaluation tool for dietary phosphorus load : A whole-foods approach

• 資料種別: 博士論文
• タイトル: Phosphatemic index is a novel evaluation tool for dietary phosphorus load : A whole-foods approach
• 著者・編者: Narasaki, Yoko; Yamasaki, Michiyo; Matsuura, Sayaka; Morinishi, Mayumi; Nakagawa, Tomomi; Matsuno, Mami; Katsumoto, Misaki; Nii, Sachi; Fushitani, Yuka; Sugihara, Kohei; Noda, Tsuneyuki; Yoneda, Takeshi; Masuda, Masashi; Yamanaka-Okumura, Hisami; Takeda, Eiji; Sakaue, Hiroshi; Yamamoto, Hironori; Taketani, Yutaka
• 著者標目: Narasaki, Yoko; Yamasaki, Michiyo; Matsuura, Sayaka; Morinishi, Mayumi; Nakagawa, Tomomi; Matsuno, Mami; Katsumoto, Misaki; Nii, Sachi; Fushitani, Yuka; Sugihara, Kohei; Noda, Tsuneyuki; Yoneda, Takeshi; Masuda, Masashi; Yamanaka-Okumura, Hisami; Takeda, Eiji; Sakaue, Hiroshi; Yamamoto, Hironori; Taketani, Yutaka
• 出版事項: Elsevier|National Kidney Foundation
• 出版年月日等: 2020-08-07
• 出版年（W3CDTF）: 2020-08-07
• 並列タイトル等: リン負荷指数は、食事性リン負荷の新たな評価指標である : 食品を用いたアプローチ; PHOSPHATEMIC INDEX EVALUATES PHOSPHORUS LOAD
• タイトル（掲載誌）: Journal of Renal Nutrition
• 巻号年月日等（掲載誌）: 30 6
• 掲載巻: 30
• 掲載号: 6
• 掲載ページ: 493-502
• ISSN（掲載誌）: ISSN : 1051-2276
• 授与機関名: 徳島大学
• 授与年月日: 2020-03-23
• 報告番号: 甲第3417号
• 学位: 博士（栄養学）
• 本文の言語コード: eng
• 件名標目: Phosphatemix Index; Dietary phosphorus bioavailability; Crossover study; Whole-foods approach
• 対象利用者: 一般
• 一般注記: Objective: Dietary phosphorus (P) restriction is crucial to treat hyperphosphatemia and reduce cardiovascular disease risk and mortality in patients with chronic kidney disease (CKD) and the wider population. Various methods for dietary P restriction exist, but the bioavailability of P in food should also be considered when making appropriate food choices to maintain patients’ quality of life. Here, we propose the ‘‘Phosphatemic Index’’ (PI) as a novel tool for evaluating dietary P load based on P bioavailability; we also evaluated the effect of continuous intake of different PI foods in mixed meals on serum intact fibroblast growth factor 23 concentration. Design and Methods: A 2-stage crossover study was conducted: Study 1: 20 healthy participants consumed 10 different foods containing 200 mg of P, and the PI was calculated from the area under the curve of a time versus serum P concentration curve; Study 2: 10 healthy participants consumed 4 different test meals (low, medium, or high PI meals or a control) over a 5-day period. Results: Study 1 showed milk and dairy products had high PI values, pork and ham had medium PI values, and soy and tofu had low PI values. In Study 2, ingestion of high PI test meals showed higher fasting serum intact fibroblast growth factor 23 levels and lower serum 1,25-dihydroxyvitamin D levels compared with ingestion of low PI test meals. Conclusion: These findings suggest that the PI can usefully evaluate the dietary P load of various foods and may help to make appropriate food choices for dietary P restriction in CKD patients.
• 記録形式（IMT）: application/pdf
• オンライン閲覧公開範囲: インターネット公開
• 関連情報（DOI）: 10.1053/j.jrn.2020.02.005
• 連携機関・データベース: 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• 提供元機関・データベース: 徳島大学 : 徳島大学機関リポジトリ

目次

http://repo.lib.tokushima-u.ac.jp/files/public/11/114726/20200512174850258377/k3417_abstract_review.pdf fulltext

http://repo.lib.tokushima-u.ac.jp/files/public/11/114726/20201109164029852392/k3417_fulltext.pdf fulltext