Ultrasound assessment of muscle mass has potential to identify patients with low muscularity at intensive care unit admission : A retrospective study

• 資料種別: 博士論文
• タイトル: Ultrasound assessment of muscle mass has potential to identify patients with low muscularity at intensive care unit admission : A retrospective study
• 著者・編者: Arai, Yuta; Nakanishi, Nobuto; Ono, Yuko; Inoue, Shigeaki; Kotani, Joji; Harada, Masafumi; Oto, Jun
• 著者標目: Arai, Yuta; Nakanishi, Nobuto; Ono, Yuko; Inoue, Shigeaki; Kotani, Joji; Harada, Masafumi; Oto, Jun
• 出版事項: European Society for Clinical Nutrition and Metabolism|Elsevier
• 出版年月日等: 2021-09-06
• 出版年（W3CDTF）: 2021-09-06
• 並列タイトル等: ICU入室時の超音波による筋量測定の有用性についての検討
• タイトル（掲載誌）: Clinical Nutrition ESPEN
• 巻号年月日等（掲載誌）: 45
• 掲載巻: 45
• 掲載ページ: 177-183
• ISSN（掲載誌）: ISSN : 2405-4577
• 授与機関名: 徳島大学
• 授与年月日: 2023-03-23
• 報告番号: 甲第3694号
• 学位: 博士（医学）
• 本文の言語コード: eng
• 件名標目: Rectus femoris muscle; Muscle mass; Ultrasound; Computed tomography; Intensive care unit
• 対象利用者: 一般
• 一般注記: Background & aims: Muscle mass is an important biomarker of survival from a critical illness; however, there is no widely accepted method for routine assessment of low muscularity at intensive care unit (ICU) admission. We hypothesize that ultrasound-based partial muscle mass assessments can reflect the trunk muscle mass. Therefore, we aimed to investigate whether ultrasound muscle mass measurements could reflect trunk muscle mass and identify patients with low muscularity. Methods: We performed a retrospective analysis of prospectively obtained ultrasound data at ICU admission. We included patients who underwent computed tomography (CT) imaging at the third lumbar vertebra (L3) within 2 days before and 2 days after ICU admission. Primary outcomes included the correlation between the femoral muscle mass measurements using ultrasound and the cross-sectional area (CSA) at L3 obtained by CT. Low muscularity was defined as a skeletal muscle index of 36.0 cm2/m2 for males and 29.0 cm2/m2 for females. Secondary outcomes included the correlation with the ultrasound measurements of the biceps brachii muscle mass and diaphragm thickness. Results: Among 133 patients, 89 underwent CT imaging, which included the L3. The patient mean age was 72 ± 13 years, and 60 patients (67%) were male. The correlation between the femoral muscle ultrasound and CT was p = 0.57 (p < 0.01, n = 89) and p = 0.48 (p < 0.01, n = 89) for quadriceps muscle layer thickness and rectus femoris muscle CSA, and these had the discriminative power to assess low muscularity, with the areas under the curve of 0.84 and 0.76, respectively. The ultrasound measurements of the biceps brachii muscle mass and diaphragm thickness were correlated with CT imaging [p = 0.57 - 0.60 (p < 0.01, n = 52) and p = 0.35 (p < 0.01, n = 79)]. Conclusions: Ultrasound measurements of muscle mass were correlated with CT measurements, and the measurements of femoral muscle mass were useful to assess low muscularity at ICU admission.
• オンライン閲覧公開範囲: インターネット公開
• 関連情報（DOI）: 10.1016/j.clnesp.2021.08.032
• 連携機関・データベース: 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• 提供元機関・データベース: 徳島大学 : 徳島大学機関リポジトリ

目次

http://repo.lib.tokushima-u.ac.jp/files/public/11/118284/20230531163456132273/k3694_abstract.pdf fulltext

http://repo.lib.tokushima-u.ac.jp/files/public/11/118284/20230531163456394843/k3694_review.pdf fulltext

http://repo.lib.tokushima-u.ac.jp/files/public/11/118284/20230531163456668025/k3694_fulltext.pdf fulltext