Estimated functional renal parenchymal volume predicts the split renal function following renal surgery.

• 資料種別: 博士論文
• タイトル: Estimated functional renal parenchymal volume predicts the split renal function following renal surgery.
• 著者・編者: Mibu, Hisakazu; Tanaka, Nobumichi; Hosokawa, Yukinari; Kumamoto, Hiromi; Marugami, Nagaaki; Hirao, Yoshihiko; Fujimoto, Kiyohide
• 著者標目: Mibu, Hisakazu; Tanaka, Nobumichi; Hosokawa, Yukinari; Kumamoto, Hiromi; Marugami, Nagaaki; Hirao, Yoshihiko; Fujimoto, Kiyohide
• 出版事項: Springer International
• 出版年月日等: 2015-10
• 出版年（W3CDTF）: 2015-10
• 並列タイトル等: 機能的腎体積測定による術後分腎機能評価の検討
• タイトル（掲載誌）: World journal of urology Vol. No. p.
• 巻号年月日等（掲載誌）: 33 10
• 掲載巻: 33
• 掲載号: 10
• 掲載ページ: 1571-1577
• ISSN（掲載誌）: ISSN : 0724-4983
• 授与機関名: 奈良県立医科大学
• 授与年月日: 2015-11-27
• 報告番号: 乙第1369号
• 学位: 博士（医学）
• 本文の言語コード: eng
• 件名標目: Renal function; Renal volume; Nephrectomy; Nephron-sparing surgery; 3-D image reconstruction
• 対象利用者: 一般
• 一般注記: type:Thesis; PURPOSE:The change in functional renal volume (FRV) has an absolute influence on renal function after nephrectomy (Nx) or nephron-sparing surgery (NSS). In this study, we prospectively examined whether the postoperative renal function following Nx and NSS could be accurately predicted and assessed the reproducibility of our newly developed 3-D image reconstruction system (Kashihara) to measure the FRV. METHODS:We enrolled 98 patients who underwent Nx and 41 patients who underwent NSS from April 2006 to September 2009 to predict postoperative FRV and renal function. FRV was measured before and after (1 month and 1 year) renal surgery. The postoperative estimated glomerular filtration rate (eGFR) was predicted from the preoperative eGFR calculated from the serum creatinine (sCr) level and the ratio of the postoperative/preoperative FRV. To assess the reproducibility and accuracy of our newly developed 3-dimensional (3-D) image reconstruction system, FRV was measured by five examiners using images obtained by CT (five cases) and MRI (five cases). RESULTS:Significant correlation was found both for FRV and for renal function between the predictive values and the actually measured values at 1 month and 1 year after surgery, not only in the Nx group, but also in the NSS group. The accuracy and reproducibility could be confirmed both with CT and MRI studies. CONCLUSIONS:The postoperative FRV and renal function could be predicted preoperatively using a 3-D image reconstructive system, preoperative routine diagnostic imaging, and preoperative sCr level.; 博士（医学）・乙第1369号・平成27年11月27日; © Springer-Verlag Berlin Heidelberg 2015; The final publication is available at Springer via http://dx.doi.org/10.1007/s00345-014-1470-7; identifier:World journal of urology Vol.33 No.10 p.1571-1577 (2015.10); identifier:07244983; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/3107; identifier:World journal of urology Vol. No. p., 33(10): 1571-1577
• オンライン閲覧公開範囲: インターネット公開
• 関連情報（DOI）: 10.1007/s00345-014-1470-7
• 連携機関・データベース: 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• 提供元機関・データベース: 奈良県立医科大学 : 奈良県立医科大学機関リポジトリ GINMU

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http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3107/1/01_%e4%b9%991369%e6%9c%ac%e6%96%87%e3%81%ae%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3107/2/02_%e4%b9%991369%e5%af%a9%e6%9f%bb%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3107/6/03_%e4%b9%991369%e6%9c%ac%e6%96%87.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3107/7/04_%e4%b9%991369Figure_1-2.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3107/8/05_%e4%b9%991369Table_1-4.pdf fulltext