Frontal lobe function in elderly patients with Alzheimer's disease and caregiver burden.

• 資料種別: 博士論文
• タイトル: Frontal lobe function in elderly patients with Alzheimer's disease and caregiver burden.
• 著者・編者: Hashimoto, Akiko; Matsuoka, Kiwamu; Yasuno, Fumihiko; Takahashi, Masato; Iida, Junzo; Jikumaru, Kiyoko; Kishimoto, Toshifumi
• 著者標目: Hashimoto, Akiko; Matsuoka, Kiwamu; Yasuno, Fumihiko; Takahashi, Masato; Iida, Junzo; Jikumaru, Kiyoko; Kishimoto, Toshifumi
• 出版事項: John Wiley & Sons, Inc
• 出版年月日等: 2017
• 出版年（W3CDTF）: 2017
• 並列タイトル等: アルツハイマー型認知症患者における前頭葉機能と介護負担の関係
• タイトル（掲載誌）: Psychogeriatrics
• 巻号年月日等（掲載誌）: 17 4
• 掲載巻: 17
• 掲載号: 4
• 掲載ページ: 267-272
• ISSN（掲載誌）: ISSN : 1346-3500
• 授与機関名: 奈良県立医科大学
• 授与年月日: 2017-03-15
• 報告番号: 甲第661号
• 学位: 博士（医学）
• 本文の言語コード: eng
• 件名標目: Alzheimer's disease; caregiver burden; dementia; frontal lobe function
• 対象利用者: 一般
• 一般注記: type:Thesis; AIM: Understanding of the relationship between caregiver burden and the degree of behavioural deficits in patients with Alzheimer's disease (AD) is relatively limited. Therefore, it is worthwhile to examine the correlations between the various relevant factors to improve the efficacy of care for patients with AD. The aim of this study was to investigate the specific contributions of frontal lobe dysfunction in AD patients to caregiver burden, while controlling for other predictor variables. METHODS: Participants included 30 pairs of caregivers and patients with AD. The Zarit Burden Interview and Frontal Assessment Battery were used to measure the caregiver burden and patients' frontal lobe function, respectively. To investigate the effects of frontal lobe dysfunction on caregiver burden, hierarchical regression equations with steps incorporating additional predictor variables were fitted. We also performed a correlation analysis between the individual subdomains of the Zarit Burden Interview and the predictor variables. RESULTS: Our study suggests that the degree of frontal lobe dysfunction in AD patients predicts their caregiver burden, when other factors of daily functional limitations and neuropsychiatric symptoms are controlled. Daily functional limitations and neuropsychiatric symptoms affected caregivers' psychosocial burden, whereas frontal lobe dysfunction affected caregivers' burden due to the increase in the dependency of the patients. CONCLUSION: Our findings indicate that to ameliorate the disabilities of patients and reduce caregiver burden, there is a need for interventions that focus on psychosocial burdens, as shown in previous studies, as well as on excessive dependency due to frontal lobe dysfunction.; 博士（医学）・甲第661号・平成29年3月15日; © 2017 Japanese Psychogeriatric Society; This is the pre-peer reviewed version of the following article: http://dx.doi.org/10.1111/psyg.12231, which has been published in final form at http://dx.doi.org/10.1111/psyg.12231. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.; identifier:Psychogeriatrics Vol.17 No.4 p.267-272 (2017 Jul); identifier:13463500; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/3311; identifier:Psychogeriatrics, 17(4): 267-272
• オンライン閲覧公開範囲: インターネット公開
• 関連情報（DOI）: 10.1111/psyg.12231
• 連携機関・データベース: 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• 提供元機関・データベース: 奈良県立医科大学 : 奈良県立医科大学機関リポジトリ GINMU

目次

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3311/1/01_%e7%94%b2661%e6%9c%ac%e6%96%87%e3%81%ae%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3311/10/02%20%e7%94%b2661%e5%af%a9%e6%9f%bb%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3311/11/03%e7%94%b2661%e6%9c%ac%e6%96%87.pdf fulltext