Higher Cognitive Function in Elderly Individuals with Previous Cataract Surgery: Cross-Sectional Association Independent of Visual Acuity in the HEIJO-KYO Cohort.

• 資料種別: 博士論文
• タイトル: Higher Cognitive Function in Elderly Individuals with Previous Cataract Surgery: Cross-Sectional Association Independent of Visual Acuity in the HEIJO-KYO Cohort.
• 著者・編者: Miyata, Kimie; Obayashi, Kenji; Saeki, Keigo; Tone, Nobuhiro; Tanaka, Kunihiko; Nishi, Tomo; Morikawa, Masayuki; Kurumatani, Norio; Ogata, Nahoko
• 著者標目: Miyata, Kimie; Obayashi, Kenji; Saeki, Keigo; Tone, Nobuhiro; Tanaka, Kunihiko; Nishi, Tomo; Morikawa, Masayuki; Kurumatani, Norio; Ogata, Nahoko
• 出版事項: Mary Ann Liebert Inc.
• 出版年月日等: 2016-06
• 出版年（W3CDTF）: 2016-06
• 並列タイトル等: 白内障手術既往のある高齢者は視力と独立して高い認知機能を維持する : 平城京コホート研究横断解析
• タイトル（掲載誌）: Rejuvenation research
• 巻号年月日等（掲載誌）: 19 3
• 掲載巻: 19
• 掲載号: 3
• 掲載ページ: 239-243
• ISSN（掲載誌）: ISSN : 1549-1684
• 授与機関名: 奈良県立医科大学
• 授与年月日: 2017-03-15
• 報告番号: 甲第666号
• 学位: 博士（医学）
• 本文の言語コード: eng
• 対象利用者: 一般
• 一般注記: type:Thesis; Cataract surgery improves visual acuity and drastically increases the capacity for light reception to the retina. Although previous studies suggested that both light exposure and visual acuity were associated with cognitive function, the relationships between cataract surgery, visual acuity, and cognitive function have not been evaluated in large populations. In this cross-sectional study, we measured cognitive function using the Mini-Mental State Examination and best-corrected visual acuity in pseudophakic (previous cataract surgery) and phakic (no previous cataract surgery) elderly individuals. Of 945 participants (mean age 71.7 years), 166 (17.6%) had pseudophakia and 317 (33.5%) had impaired cognitive function (score ≤26). The pseudophakic group showed significantly better visual acuity than the phakic group (p = 0.003) and lower age-adjusted odds ratio (ORs) for cognitive impairment (OR 0.66; p = 0.038). Consistently, in multivariate logistic regression models, after adjusting for confounding factors, including visual acuity and socioeconomic status, ORs for cognitive impairment were significantly lower in the pseudophakic group than in the phakic group (OR 0.64; 95% confidence interval 0.43-0.96; p = 0.031). This association remained significant in sensitivity analysis, excluding participants with low cognitive score ≤23 (n = 36). In conclusion, in a general elderly population, prevalence of cognitive impairment was significantly lower in pseudophakic individuals independently of visual acuity. The association was also independent of several major causes of cognitive impairment such as aging, gender, obesity, socioeconomic status, hypertension, diabetes, sleep disturbances, depressive symptoms, and physical inactivity.; 博士（医学）・甲第666号・平成29年3月15日; © Mary Ann Liebert, Inc.; This is a non-final version of an article published in final form in "http://dx.doi.org/10.1089/rej.2015.1718"; identifier:Rejuvenation research Vol.19 No.3 p.239-243 (2016 Jun); identifier:15491684; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/3319; identifier:Rejuvenation research, 19(3): 239-243
• オンライン閲覧公開範囲: インターネット公開
• 関連情報（DOI）: 10.1089/rej.2015.1718
• 連携機関・データベース: 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• 提供元機関・データベース: 奈良県立医科大学 : 奈良県立医科大学機関リポジトリ GINMU

目次

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3319/1/01_%e7%94%b2666%e6%9c%ac%e6%96%87%e3%81%ae%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3319/2/02_%e7%94%b2666%e5%af%a9%e6%9f%bb%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3319/10/03%20%e7%94%b2666%e6%9c%ac%e6%96%87.pdf fulltext