Accuracy of magnetic resonance imaging in predicting dentate line invasion in low rectal cancer.

• 資料種別: 博士論文
• タイトル: Accuracy of magnetic resonance imaging in predicting dentate line invasion in low rectal cancer.
• 著者・編者: Tatsumoto, Shota; Itoh, Takahiro; Takahama, Junko; Marugami, Nagaaki; Minamiguchi, Kiyoyuki; Tanaka, Toshihiro; Koyama, Fumikazu; Morita, Kohei; Kichikawa, Kimihiko
• 著者標目: Tatsumoto, Shota; Itoh, Takahiro; Takahama, Junko; Marugami, Nagaaki; Minamiguchi, Kiyoyuki; Tanaka, Toshihiro; Koyama, Fumikazu; Morita, Kohei; Kichikawa, Kimihiko
• 出版事項: Springer
• 出版年月日等: 2020-06
• 出版年（W3CDTF）: 2020-06
• 並列タイトル等: 下部直腸癌におけるMRIを用いた歯状線浸潤の診断精度
• タイトル（掲載誌）: Japanese journal of radiology
• 巻号年月日等（掲載誌）: 38 6
• 掲載巻: 38
• 掲載号: 6
• 掲載ページ: 539-546
• ISSN（掲載誌）: ISSN : 1867-1071
• 授与機関名: 奈良県立医科大学
• 授与年月日: 2020-06-30
• 報告番号: 甲第748号
• 学位: 博士（医学）
• 本文の言語コード: eng
• 件名標目: Anal canal; Dentate line; Magnetic resonance imaging; Rectal cancer; Rectum
• 対象利用者: 一般
• 一般注記: type:Thesis; Purpose: To retrospectively assess the accuracy of magnetic resonance imaging (MRI) in predicting dentate line invasion in low rectal cancer. Materials and methods: Eighty-one patients with primary rectal cancer were assessed by dynamic contrast-enhanced MRI. The location of the dentate line was assessed on MRI in 27 patients with upper-mid rectal cancer. Two observers independently evaluated the distance between the distal tumor edge and the MRI-defined dentate line in 54 patients with low rectal cancer, and the imaging and histological findings were compared. Results: The MRI-defined dentate line was 24.0 ± 3.8 mm above the anal verge in patients with upper-mid rectal cancer. The dentate line invasion status agreed with the histological findings in 49/54 (91%) patients (κ = 0.72 [95% CI 0.50-0.95]) for observer 1, and in 51/54 (94%) patients (κ = 0.83 [0.65-1.00]) for observer 2 in patients with low rectal cancer. Interobserver agreement was good (κ = 0.83 [0.65-1.00]). The MRI-derived distance between the distal tumor edge and the dentate line had significant correlation with the histological distance (r = 0.86 for reader 1 and 0.75 for observer 2). Conclusion: MRI demonstrates high accuracy in predicting dentate line invasion in low rectal cancer.; 博士（医学）・甲第748号・令和2年6月30日; © Japan Radiological Society 2020; © 2020 Springer Nature Switzerland AG. Part of Springer Nature.; This is a post-peer-review, pre-copyedit version of an article published in Japanese journal of radiology. The final authenticated version is available online at: http://dx.doi.org/10.1007/s11604-020-00933-5.; identifier:Japanese journal of radiology Vol.38 No.6 p.539-546 (2020 Jun); identifier:18671071; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/3755; identifier:Japanese journal of radiology, 38(6): 539-546
• オンライン閲覧公開範囲: インターネット公開
• 関連情報（DOI）: 10.1007/s11604-020-00933-5
• 連携機関・データベース: 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• 提供元機関・データベース: 奈良県立医科大学 : 奈良県立医科大学機関リポジトリ GINMU

目次

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3755/1/01%e7%94%b2748%e6%9c%ac%e6%96%87%e3%81%ae%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3755/2/02%e7%94%b2748%e5%af%a9%e6%9f%bb%e8%a6%81%e6%97%a8.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3755/6/03%e7%94%b2748%e6%9c%ac%e6%96%87.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3755/7/04%e7%94%b2748Fig.01-07.pdf fulltext

http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/3755/8/05%e7%94%b2748Supplementary%20file.pdf fulltext