Influence of Depression on the Association between Colder Indoor Temperature and Higher Blood Pressure

• 資料種別: 博士論文
• タイトル: Influence of Depression on the Association between Colder Indoor Temperature and Higher Blood Pressure
• 著者・編者: Okumura, Kazuki; Obayashi, Kenji; Tai, Yoshiaki; Yamagami, Yuki; Kurumatani, Norio; Saeki, Keigo
• 著者標目: Okumura, Kazuki; Obayashi, Kenji; Tai, Yoshiaki; Yamagami, Yuki; Kurumatani, Norio; Saeki, Keigo
• 出版事項: Wolters Kluwer
• 出版年月日等: 2022-10-01
• 出版年（W3CDTF）: 2022-10-01
• 並列タイトル等: うつ症状が室温低値と血圧高値の関連に及ぼす影響
• タイトル（掲載誌）: Journal of hypertension
• 巻号年月日等（掲載誌）: 40 10
• 掲載巻: 40
• 掲載号: 10
• 掲載ページ: 2013-2021
• ISSN（掲載誌）: ISSN : 0263-6352
• 授与機関名: 奈良県立医科大学
• 授与年月日: 2023-03-15
• 報告番号: 甲第859号
• 学位: 博士（医学）
• 本文の言語コード: eng
• 件名標目: Ambulatory blood pressure monitoring; Cold exposure; Depression; Epidemiologic study; Hypertension; Indoor temperature; Older adults
• 対象利用者: 一般
• 一般注記: 出版タイプ： VoR; type:Thesis; Objectives: Cold exposure accounts for more than 7% of all-cause mortality worldwide, and cold-induced blood pressure (BP) elevation and consequent cardiovascular events are partially responsible. For prevention, it is important to identify risk factors for exaggerated temperature-sensitivity of BP but this is not fully understood. This study investigated whether depressive symptoms affect the relationship between indoor temperature and BP. Methods: We conducted a cross-sectional analysis of 1076 community-based individuals who were at least 60 years of age. Depressive symptoms were assessed using the 15-item Geriatric Depression Scale at a cutoff point of 4/5. We performed ambulatory BP monitoring and indoor temperature measurement on two consecutive days during the cold season in Nara, Japan. Results: When using daytime SBP as a dependent variable, multilevel linear regression analyses showed that lower daytime indoor temperature was significantly associated with higher daytime SBP in the depressive group (n = 216, β = -0.804, P < 0.001) but not in the nondepressive group (n = 860, β = -0.173, P = 0.120); moreover, a significant interaction between depression and daytime indoor temperature was observed (P = 0.014). These relationships were independent of potential confounders including age, gender, BMI, medications, and physical activity. Similar results were obtained for morning SBP, nocturnal SBP dipping, and morning BP surge. Conclusion: The results suggest that depressive participants are more likely to have cold-induced BP elevation than nondepressive participants. Further longitudinal studies are warranted to determine whether people with depressive symptoms are at a high risk for cold-related cardiovascular events.; 博士（医学）・甲第859号・令和5年3月15日; © 2022 Wolters Kluwer Health, Inc. All rights reserved. This is a non-final version of an article published in final form in Okumura, Kazuki et al. Influence of depression on the association between colder indoor temperature and higher blood pressure. Journal of Hypertension. 2022, 40(10), p.2013-2021, doi: 10.1097/HJH.0000000000003221.; identifier:Journal of Hypertension Vol.40 No.10 p.2013-2021 (2022 Oct); identifier:02636352; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/4090; identifier:Journal of hypertension, 40(10): 2013-2021
• 一次資料へのリンクURL: fulltext; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/4090/1/01%e7%94%b2859%e6%9c%ac%e6%96%87%e3%81%ae%e8%a6%81%e6%97%a8.pdf; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/4090/2/02%e7%94%b2859%e5%af%a9%e6%9f%bb%e8%a6%81%e6%97%a8.pdf; http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/4090/6/03%e7%94%b2859%e6%9c%ac%e6%96%87.pdf
• オンライン閲覧公開範囲: インターネット公開
• 関連情報（DOI）: 10.1097/HJH.0000000000003221; https://doi.org/10.1097/HJH.0000000000003221
• 掲載誌（NCID）: AA10644107; https://ci.nii.ac.jp/ncid/AA10644107
• 連携機関・データベース: 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• 提供元機関・データベース: 奈良県立医科大学 : 奈良県立医科大学機関リポジトリ GINMU