The low carriage prevalence of pneumococcus among community-dwelling older people: A cross-sectional study in Japan

• 資料種別: 博士論文
• タイトル: The low carriage prevalence of pneumococcus among community-dwelling older people: A cross-sectional study in Japan
• 著者・編者: 安田, 一行
• 著者標目: 安田, 一行
• 出版事項: Elsevier Ltd.
• 出版年月日等: 2020-09-18
• 出版年（W3CDTF）: 2020-09-18
• 並列タイトル等: 本邦の地域在住高齢者における肺炎球菌保菌に関する横断研究
• タイトル（掲載誌）: Vaccine
• 巻号年月日等（掲載誌）: 38 21
• 掲載巻: 38
• 掲載号: 21
• 掲載ページ: 3752-3758
• ISSN（掲載誌）: ISSN : 0264-410X
• 授与機関名: Nagasaki University (長崎大学)
• 授与年月日: 2020-09-18
• 報告番号: 甲医歯薬第1267号
• 学位: 博士(医学)
• 本文の言語コード: eng
• 件名標目: Streptococcus pneumoniae; Pneumococcus; Carriage prevalence; Community-dwelling; Older people; Superaged society
• 対象利用者: 一般
• 一般注記: 出版タイプ： VoR; Background: The carriage prevalence of pneumococcus among community-dwelling older adults is not fully understood, especially in superaged societies. Our purpose was to elucidate the carriage prevalence of pneumococcus in the upper respiratory tract among Japanese community-dwelling adults aged ?65 years. Methods: We conducted a cross-sectional study of generally healthy community-dwelling adults aged ?65 years in Nagasaki city, Japan. Demographic and clinical data and nasopharyngeal, oropharyngeal and saliva samples were collected from February 21st, 2018, to December 17th, 2018. The specimens were tested by culture and molecular methods. Results: Among a total of 504 enrolled participants, none were positive for pneumococcus by culture, and 22 were positive by PCR. The overall carriage prevalence was 4.4% (95% CI: 2.8?6.5%). The prevalence was highest in saliva samples, followed by oropharyngeal and nasopharyngeal samples. No demographic characteristics were associated with carriage prevalence, including age (4.7% among participants aged 65?74 years and 4.1% among those 75 years and older). Among the pneumococcal-positive participants, 18.2% were PCV13-covered serotypes. Conclusions: Our data suggest a low carriage prevalence of S. pneumoniae among community-dwelling older people in Japan.; 長崎大学学位論文 学位記番号:博(医歯薬)甲第1267号 学位授与年月日:令和2年9月18日; Author: Ikkoh Yasuda, Motoi Suzuki, Bhim Gopal Dhoubhadel, Mayumi Terada, Akira Satoh, Eiichiro Sando, Tomoko Hiraoka, Masaki Kurihara, Nobuo Matsusaka, Fumitaka Kawahara, Koya Ariyoshi, Konosuke Morimoto; Citation: Vaccine, 38(21), pp.3752-3758; 2020; identifier:Nagasaki University (長崎大学), 博士(医学) (2020-09-18)
• 一次資料へのリンクURL: fulltext; https://nagasaki-u.repo.nii.ac.jp/?action=repository_action_common_download&item_id=48&item_no=1&attribute_id=70&file_no=1
• オンライン閲覧公開範囲: インターネット公開
• 著作権情報: c 2020 Elsevier Ltd. All rights reserved.
• 関連情報: http://hdl.handle.net/10069/40271
• 関連情報（DOI）: 10.1016/j.vaccine.2020.03.033; https://doi.org/10.1016/j.vaccine.2020.03.033
• 連携機関・データベース: 国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）; https://irdb.nii.ac.jp
• 提供元機関・データベース: 長崎大学 : 長崎大学学術研究成果リポジトリ