並列タイトル等三次元リングを使用した三尖弁形成術後の三尖弁閉鎖不全症再燃のリスク因子の検討
タイトル(掲載誌)Acta Medica Nagasakiensia
授与機関名Nagasaki University (長崎大学)
一般注記Objective: The purpose of this study was to investigate the results of tricuspid valve (TV) repair with three-dimensional ring (3DR) and risk factors of recurrent tricuspid regurgitation (TR).Methods: We retrospectively investigated 171 patients who underwent TV repair with a 3DR for TR from 2007 to 2016 at our institution. The patients were divided into the non-Recurrence group (<2+ TR) and Recurrence group (≥2+ TR), and compared to identify the cause of recurrent TR. The mean follow-up period was 58±35 months.Results: The preoperative TR grade was 3.0±0.8. A total of 22 patients had at least ≥2+ TR in the follow-up period. Freedom from ≥2+ TR and re-operation at 5 years were 83.6±3.3% and 97.9±2.1%. Comparison of the non-Recurrence and Recurrence groups revealed significant differences in the preoperative TR grade (2.9±0.8 and 3.4±0.6, p=0.008), proportion of the patients with left ventricular ejection fraction (LVEF) <40% (9% and 32%, p=0.003) and right ventricular end-systolic dimension (RVDs, 22.8±7.1 mm and 31.1±12.3 mm, P=0.001). In the multivariate analysis, LVEF <40% (hazard ratio: 12.65, 95% confidence interval: 2.66–60.18; p=0.002) and RVDs (hazard ratio: 1.08, 95% confidence interval: 1.02–1.14; p=0.02) were identified as risk factors for recurrent TR.Conclusion: Our results of TV repair with 3DR were of satisfactory. However, patients with preoperative lower LVEF and larger RVDs were identified at risk of recurrent TR. This result suggests the limitation to use of 3DR alone for TV repair and need for additional procedure.
長崎大学学位論文 学位記番号:博(医歯薬)甲第1421号 学位授与年月日:令和4年3月18日
Author: Tessho Kitamura, Kikuko Obase, Shun Nakaji, Ichiro Matsumaru, Takashi Miura, Kiyoyuki Eishi
Citation: Acta Medica Nagasakiensia, 65(3), pp. 103-109; 2022
identifier:Nagasaki University (長崎大学), 博士(医学) (2022-03-18)
一次資料へのリンクURLhttps://nagasaki-u.repo.nii.ac.jp/?action=repository_action_common_download&item_id=27578&item_no=1&attribute_id=70&file_no=1 (fulltext)
著作権情報(C) 2022 Nagasaki University School of Medicine
関連情報http://hdl.handle.net/10069/41424
連携機関・データベース国立情報学研究所 : 学術機関リポジトリデータベース(IRDB)(機関リポジトリ)