並列タイトル等Relationship between pharyngeal airway depth and ventilation condition in mandibular setback surgery : A computational fluid dynamics study
学位博士(歯学)
Doctor of Philosophy in Dental Science
一般注記博士論文全文, 博士論文要旨, 最終試験結果の要旨, 論文審査の要旨
Objectives: This study aimed to determine the anteroposterior depth (APD) of the pharyngeal airway (PA) where post-operative PA obstruction was predicted, using computer fluid dynamics (CFD), in order to prevent obstructive sleep apnoea after mandibular setback surgery.
Settings and sample population: Nineteen skeletal Class III patients (8 men; mean age, 26.7 years) who required mandibular setback surgery had computed tomography images taken before and 6 months after surgery.
Methods: The APD of each site of the four cross-sectional reference planes (retropalatal airway [RA], second cervical vertebral airway, oropharyngeal airway and third cervical vertebral airway) were measured. The Maximum negative pressure (Pmax) of the PA was measured at inspiration using CFD, based on a three-dimensional PA model. Intersite differences were determined using analysis of variance and the Friedman test with Bonferroni correction. The relationship between APD and Pmax was evaluated by Spearman correlation coefficients and non-linear regression analysis.
Results: The smallest PA site was the RA. Pmax was significantly correlated with the APD of the RA (rs = .628, P < .001). The relationship between Pmax and the APD-RA was fitted to a curve, which showed an inversely proportional relationship of Pmax to the square of the APD-RA. Pmax substantially increased even with a slight reduction of the APD-RA. In particular, when the APD-RA was 7 mm or less, Pmax increased greatly, suggesting that PA obstruction was more likely to occur.
Conclusions: The results of this study suggest that APD-RA is a useful predictor of good PA ventilation after surgery.
This is the peer reviewed version of the following article:
Yoshito Shirazawa, Tomonori Iwasaki, Kazuhiro Ooi, Yutaka Kobayashi, Ayaka Yanagisawa-Minami, Yoichiro Oku, Anna Yokura, Yuusuke Ban, Hokuto Suga, Shuichi Kawashiri, Youichi Yamasaki.
Relationship between pharyngeal airway depth and ventilation condition in mandibular setback surgery: A computational fluid dynamics study
Orthodontics & Craniofacial Research (2020), 23(3), 313-322
© 2020 John Wiley & Sons A/S.
which has been published in final form at https://doi.org/10.1111/ocr.12371
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連携機関・データベース国立情報学研究所 : 学術機関リポジトリデータベース（IRDB）（機関リポジトリ）