一般注記application/pdf
We enrolled 196 patients with hypertension who were already being treated with free-drug combinations of angiotensin-II receptor blocker (ARB) and amlodipine. The free-drug combinations of ARB and amlodipine were replaced with the same dose of the fixed-dose combinations. The average home blood pressure (BP) in all patients receiving fixed-dose combinations was significantly lower than those receiving fixed-dose combinations (131±10/75±8vs. 136±11/77±9mm H g,P<.01) accompanied with increasing drug adherence. After lowering BP by fixed-dose combinations, the costs for medications decreased by 31 % over the 3 months.
本文 / Department of Cardiology and Nephrology, Mie University Graduate School of Medicine
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http://dx.doi.org/10.3109/10641963.2012.732644
DOIinfo:doi/10.3109/10641963.2012.732644
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