Relationship between frequency spectrum of heart rate variability and autonomic nervous activities during sleep in newborns. 3

• 資料種別: 博士論文
• タイトル: Relationship between frequency spectrum of heart rate variability and autonomic nervous activities during sleep in newborns.
• 巻次・部編番号: 40 3
• 著者・編者: Takatani, Tsunenori; Takahashi, Yukihiro; Yoshida, Ryota; Imai, Ryuko; Uchiike, Takao; Yamazaki, Masaharu; Shima, Midori; Nishikubo, Toshiya; Ikada, Yoshito; Fujimoto, Shinichi
• 著者標目: Takatani, Tsunenori; Takahashi, Yukihiro; Yoshida, Ryota; Imai, Ryuko; Uchiike, Takao; Yamazaki, Masaharu; Shima, Midori; Nishikubo, Toshiya; Ikada, Yoshito; Fujimoto, Shinichi
• 出版事項: Elsevier
• 出版年月日等: 2018-03; 40 3
• 出版年（W3CDTF）: 2018-03
• 並列タイトル等: 新生児の睡眠中の心拍変動周波数スペクトルと自律神経活動の関係
• タイトル（掲載誌）: Brain and development
• 掲載ページ: 165-171
• ISSN（掲載誌）: 03877604
• 授与機関名: 奈良県立医科大学
• 授与年月日: 2018-03-15
• 授与年月日（W3CDTF）: 2018-03-15
• 報告番号: 乙第1418号
• 学位: 博士（医学）
• 博論授与番号: 乙第1418号
• 本文の言語コード: eng
• 件名標目: EEG; Autonomic nervous system; Neonatal sleep; Heart rate variability
• 対象利用者: 一般
• 一般注記: type:Thesis; INTRODUCTION: We analyzed the frequency spectrum of two neonatal sleep stages, namely active sleep and quiet sleep, and the relationship between these sleep stages and autonomic nervous activity in 74 newborns and 16 adults as a comparison. METHOD: Active and quiet sleep were differentiated by electroencephalogram (EEG) patterns, eye movements, and respiratory wave patterns; autonomic activity was analyzed using the RR interval of simultaneously recorded electrocardiogram (ECG) signals. Power values (LFa, absolute low frequency; HFa, absolute high frequency), LFa/HFa ratio, and the values of LFn (normalized low frequency) and HFn (normalized high frequency) were obtained. Synchronicity between the power value of HFa and the LFa/HFa ratio during active and quiet sleep was also examined by a new method of chronological demonstration of the power values of HFa and LFa/HFa. RESULTS: We found that LFa, HFa and the LFa/HFa ratio during active sleep were significantly higher than those during quiet sleep in newborns; in adults, on the other hand, the LFa/HFa ratio during rapid eye movement (REM) sleep, considered as active sleep, was significantly higher than that during non-REM sleep, considered as quiet sleep, and HFa values during REM sleep were significantly lower than those during non-REM sleep. LFn during quiet sleep in newborns was significantly lower than that during active sleep. Conversely, HFn during quiet sleep was significantly higher than that during active sleep. Analysis of the four classes of gestational age groups at birth indicated that autonomic nervous activity in a few preterm newborns did not reach the level seen in full-term newborns. Furthermore, the power value of HFa and the LFa/HFa ratio exhibited reverse synchronicity. CONCLUSION: These results indicate that the autonomic patterns in active and quiet sleep of newborns are different from those in REM and non-REM sleep of adults and may be develop to the autonomic patterns in adults, and that parasympathetic activity is dominant during quiet sleep as compared to active sleep from the results of LFn and HFn in newborns. In addition, in some preterm infants, delayed development of the autonomic nervous system can be determined by classifying the autonomic nervous activity pattern of sleep stages.; 博士（医学）・乙第1418号・平成30年3月15日; © 2017 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.; identifier:Brain and development Vol.40 No.3 p.165-171 (2018 Mar); identifier:03877604; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/3434; identifier:Brain and development, 40(3): 165-171
• 国立国会図書館永続的識別子: info:ndljp/pid/11098911; https://dl.ndl.go.jp/pid/11098911
• コレクション（共通）: 障害者向け資料
• コレクション（障害者向け資料：レベル1）: テキストデータ
• コレクション（個別）: 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• 収集根拠: 博士論文（自動収集）
• 受理日（W3CDTF）: 2018-06-04T01:14:06+09:00
• 記録形式（IMT）: application/pdf
• オンライン閲覧公開範囲: 国立国会図書館内限定公開
• デジタル化資料送信: 図書館・個人送信対象外
• 遠隔複写可否（NDL）: 可
• 関連情報（URI）: https://doi.org/10.1016/j.braindev.2017.09.003
• 掲載誌（URI）: http://hdl.handle.net/10564/3434
• 連携機関・データベース: 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

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