並列タイトル等胃がんリスク評価におけるABC分類とX線所見の関連性について
タイトル（掲載誌）Japanese journal of radiology
一般注記type:Thesis
PURPOSE:To investigate the correlation between ABC risk assessment and radiological findings of gastric mucosa and to propose an improved method for gastric cancer screening.MATERIALS AND METHODS:We evaluated 318 participants with Helicobacter pylori (Hp) antibody titers, serum pepsinogen (PG) and upper GI radiography and then classified them into three groups: A, double-negative; B, Hp-positive, PG-negative; C, PG-positive. Group A was subclassified as: A-1, Hp antibody titer <3.0 U/ml; A-2, Hp antibody titer ≥3.0 U/ml. Results for group A and non-A (B or C) participants and radiological findings of gastric mucosa (fold and area gastricae) were analyzed retrospectively.RESULTS:Radiological findings differed significantly between the 207 A-1 and 98 non-A group. Odds ratios were 17.72 for fold distribution, 10.63 for fold thickness, 6.10 for fold characteristics, and 10.62 for area gastricae. Presence of ≥2 risk factors offered 90.3 % sensitivity, 94.7 % specificity, and 93.3 % accuracy. Nine (69.2 %) of the 13 A-2 group participants and 11 (5.3 %) A-1 group participants had a risk for gastric cancer according to radiological findings.CONCLUSION:A good correlation exists between ABC classifications and radiological findings for gastric cancer risk, but some discrepant cases exist. We recommend both methods as screening for gastric cancer.
博士（医学）・乙第1370号・平成27年11月27日
© Japan Radiological Society 2015
© Springer-Verlag Berlin Heidelberg 2015
The final publication is available at Springer via http://dx.doi.org/10.1007/s11604-015-0469-3
identifier:Japanese journal of radiology Vol.33 No.10 p.636-644 (2015.10)
identifier:18671071
identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/3108
identifier:Japanese journal of radiology, 33(10): 636-644
DOIinfo:doi/10.1007/s11604-015-0469-3
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