Intestinal helminth infections in HIV-infected patients in Savannakhet after establishment of an HIV registration network in Lao People’s Democratic Republic

• 資料種別: 記事
• タイトル: Intestinal helminth infections in HIV-infected patients in Savannakhet after establishment of an HIV registration network in Lao People’s Democratic Republic
• 著者・編者: Yukako Kaneshiro; Khamphang Sourinphoumy; Naoki Imaizumi
• 出版事項: 日本 : Springer Nature
• 出版年月日等: 2019-02-11
• 出版年（W3CDTF）: 2019-02-11
• タイトル（掲載誌）: Tropical medicine and health
• 巻号年月日等（掲載誌）: 47(14)
• 掲載巻: 47(14)
• ISSN（掲載誌）: 1349-4147
• ISSN-L（掲載誌）: 1348-8945
• 本文の言語コード: eng
• DOI: 10.1186/s41182-019-0142-0; https://doi.org/10.1186/s41182-019-0142-0
• 国立国会図書館永続的識別子: info:ndljp/pid/11285308; https://dl.ndl.go.jp/pid/11285308
• コレクション（共通）: 障害者向け資料
• コレクション（障害者向け資料：レベル1）: テキストデータ
• コレクション（個別）: 国立国会図書館デジタルコレクション > 電子書籍・電子雑誌 > その他; https://dl.ndl.go.jp/collections/B00035
• 収集根拠: オンライン資料収集制度
• 受理日（W3CDTF）: 2019-05-18T07:46:57+09:00
• 保存日（W3CDTF）: 2019-05-18
• 記録形式（IMT）: application/pdf
• オンライン閲覧公開範囲: 国立国会図書館内限定公開
• デジタル化資料送信: 図書館・個人送信対象外
• 遠隔複写可否（NDL）: 可
• 掲載誌（URI）: http://tropmedhealth.biomedcentral.com/articles
• 掲載誌（国立国会図書館永続的識別子）: info:ndljp/pid/11285294; https://dl.ndl.go.jp/pid/11285294
• 連携機関・データベース: 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

• 要約等: Background: In Lao People’s Democratic Republic (PDR), which borders China, Vietnam, Cambodia, Thailand, and Myanmar, the number of HIV-infected patients has increased in recent years. HIV-infected patients diagnosed in Lao PDR are enrolled in a registration network and receive antiretroviral therapy (ART) covered by governmental financial support. Based on the registration network, we investigated intestinal helminth infections and coinfection with HTLV-1 in HIV-infected patients treated with an early intervention using ART in Lao PDR.\nMethods: This cross-sectional study of all 252 HIV-infected patients at Savannakhet Provincial Hospital, located in the southern part of Lao PDR, was conducted between February and March 2018. Socioepidemiological information and clinical information were collected from a registration network database and by questionnaire administered to participants. Microscopic examination of intestinal helminth infections in stool samples and particle agglutination for anti-HTLV-1 antibody in plasma were performed.\nResults: The median age of all 252 participants was 39 years old (range, 18–59). Based on the registration network database, there were 156 (61.9%) HIV-infected patients with a CD4-positive cell count ≥ 200 cells/μL and 146 (57.9%) with an HIV viral load < 250 copies/mL. Among 212 stool samples, 75 (35.4%) were found to contain one or more intestinal helminth species, including Opisthorchis viverrini (16.5%), Strongyloides stercoralis (10.8%), hookworm (10.4%), and Taenia saginata (3.3%). This rate of intestinal helminth infections was lower than that of a previous report conducted before the establishment of the registration network for HIV-infected patients in Lao PDR. There was no significant association between intestinal helminth infections and a lower CD4-positive T cell count or higher HIV viral load. HIV-infected patients with anti-HTLV-1 antibody positivity were not found in this cohort.\nConclusion: The registration network and an early intervention using ART may provide good medical care and improve the clinical course of HIV-infected patients in Lao PDR. However, the incidence of intestinal helminth infections remains high at 35.4%. The development of a specific medical care system for helminth infection for HIV-infected patients is necessary.; 論文
• DOI: 10.1186/s41182-019-0142-0; https://doi.org/10.1186/s41182-019-0142-0
• オンライン閲覧公開範囲: インターネット公開
• 著作権情報: Creative Commons Attribution 4.0; https://creativecommons.org/licenses/by/4.0/
• 関連情報（URI）: http://hdl.handle.net/20.500.12000/47230; https://u-ryukyu.repo.nii.ac.jp/records/2011223; http://id.ndl.go.jp/digimeta/11285308; https://dl.ndl.go.jp/pid/11285308; http://link.springer.com/content/pdf/10.1186/s41182-019-0142-0.pdf; http://link.springer.com/article/10.1186/s41182-019-0142-0/fulltext.html; https://search.jamas.or.jp/link/ui/2020369335
• 参照: A new diagnostic algorithm using biopsy specimens in adult T-cell leukemia/lymphoma: combination of RNA in situ hybridization and quantitative PCR for HTLV-1; https://cir.nii.ac.jp/crid/1360290617827696896
• 参照: Helminth infection in southern Laos: high prevalence and low awareness; https://cir.nii.ac.jp/crid/1360011144850157312; Intestinal parasitic infections in relation to HIV/AIDS status, diarrhea and CD4 T-cell count; https://cir.nii.ac.jp/crid/1360292618695409024; Strongyloidiasis in Patients with Hematologic Malignancies; https://cir.nii.ac.jp/crid/1360855568664033280; Effects of HIV-1 infection on malaria parasitemia in milo sub-location, western Kenya; https://cir.nii.ac.jp/crid/1360855569147783680; Coinfection by HTLV-I/II is associated with an increased risk of strongyloidiasis and delay in starting antiretroviral therapy for AIDS patients; https://cir.nii.ac.jp/crid/1361418518561006720; Strongyloidiasis in a patient with acquired immunodeficiency syndrome; https://cir.nii.ac.jp/crid/1361418519911102464; Molecular epidemiology of HIV, HBV, HCV, and HTLV-1/2 in drug abuser inmates in central Javan prisons, Indonesia; https://cir.nii.ac.jp/crid/1361418521180313600; Clinical, endoscopic and histopathological profiles of parasitic duodenitis cases diagnosed by upper digestive endoscopy; https://cir.nii.ac.jp/crid/1361699993501874688; Women experience a better long-term immune recovery and a better survival on HAART in Lao People’s Democratic Republic; https://cir.nii.ac.jp/crid/1361699993725253504; Intestinal Parasitic Infections in HIV-Infected Patients, Lao People’s Democratic Republic; https://cir.nii.ac.jp/crid/1361699994822934656; HTLV-1/2 seroprevalence and coinfection rate in Brazilian first-time blood donors: an 11-year follow-up; https://cir.nii.ac.jp/crid/1361699995825838464; Parasite infections in AIDS; https://cir.nii.ac.jp/crid/1361981468942647296; Physical activity among HIV-positive patients receiving antiretroviral therapy in Hanoi and Nam Dinh, Vietnam: a cross-sectional study; https://cir.nii.ac.jp/crid/1361981471303746688; Dissemination of <i>Strongyloides stercoralis</i> as an immune restoration phenomenon in an HIV-1-infected man on antiretroviral therapy; https://cir.nii.ac.jp/crid/1361981471370059520; No Evidence of HTLV-I or HTLV-II Infection Among the Hmong People of Northern Thailand or Injecting Drug Users in Bangkok; https://cir.nii.ac.jp/crid/1363107368981106176; The global burden of intestinal nematode infections — Fifty years on; https://cir.nii.ac.jp/crid/1363107370501165184; <i>Strongyloides stercoralis</i> Infection in AIDS; https://cir.nii.ac.jp/crid/1363388843613032064; Intestinal parasitic infection among the HIV-infected patients in Nepal; https://cir.nii.ac.jp/crid/1363670319350501760; Epidemiology and immunology of helminth–HIV interactions; https://cir.nii.ac.jp/crid/1364233268848940928; Strongyloidiasis and Infection Due to Human Immunodeficiency Virus: 25 Cases at a Brazilian Teaching Hospital, Including Seven Cases of Hyperinfection Syndrome; https://cir.nii.ac.jp/crid/1364233271072793856
• 連携機関・データベース: 国立情報学研究所 : CiNii Research; https://cir.nii.ac.jp/
• 提供元機関・データベース: 学術機関リポジトリデータベース; https://irdb.nii.ac.jp; 雑誌記事索引データベース; https://ndlsearch.ndl.go.jp; Crossref; https://www.crossref.org; CiNii Articles; 科学研究費助成事業データベース; https://kaken.nii.ac.jp/ja
• 書誌ID（NDLBibID）: 11285308; http://id.ndl.go.jp/bib/11285308
• NII論文ID: 120006937801

• 要約等: 本研究は、奈良町に残る伝統的町家に対する価値意識と保存再生手法の評価を推計し明確化することを目的とする。奈良町の居住者や店舗経営者のような奈良町生活者と奈良町への来訪者に対して、町家の各価値要素と保存再生手法案の比較をそれぞれ行い、さらに仮想的な質問として、町家の現状を踏まえた上で町家の保存再生に向けた寄付金への支払意志額を尋ねる調査を行った。その調査結果をもとに、CVMを用いて町家の評価を定量的に推計し、AHPを用いて奈良町町家に対する価値構成と保存再生手法の評価を明らかにした。訪問者と同様に属性の異なる市民グループとの比較を行った。その結果、（1）奈良町町家に対する評価は、京都や金沢の研究事例に比べ低く捉えられている（2）文化的価値の認識が支払動機につながると考えられる（3）文化的価値を重視すると考えられる保存再生手法はあるが、奈良町生活者は外壁のみ町家を保持し内部は現代風に再生する手法を最も重視していることが明らかとなった。
• DOI: 10.11361/journalcpij.46.223; https://doi.org/10.11361/journalcpij.46.223
• 関連情報（URI）: http://id.ndl.go.jp/bib/11285308; https://ndlsearch.ndl.go.jp/books/R000000004-I11285308; https://www.jstage.jst.go.jp/article/journalcpij/46/3/46_3_223/_pdf
• 連携機関・データベース: 国立情報学研究所 : CiNii Research; https://cir.nii.ac.jp/
• 提供元機関・データベース: Japan Link Center; https://japanlinkcenter.org/top; 雑誌記事索引データベース; https://ndlsearch.ndl.go.jp; Crossref; https://www.crossref.org; CiNii Articles
• 書誌ID（NDLBibID）: 11285308; http://id.ndl.go.jp/bib/11285308
• NII論文ID: 10030401388