Artificial in vitro biosynthesis systems for the development of pseudo-natural products
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DOI[10.1246/bcsj.20170379]のデータに遷移します
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- 資料種別
- 記事
- 著者・編者
- Yuki GotoHiroaki Suga
- 出版年月日等
- 2018-02-28
- 出版年（W3CDTF）
- 2018-02-28
- タイトル（掲載誌）
- Bulletin of the Chemical Society of Japan
- 巻号年月日等（掲載誌）
- 91(3)
- 掲載巻
- 91(3)
- ISSN（掲載誌）
- 1348-0634
- ISSN-L（掲載誌）
- 0009-2673
- 本文の言語コード
- eng
- DOI
- 10.1246/bcsj.20170379
- 国立国会図書館永続的識別子
- info:ndljp/pid/11343758
- コレクション（共通）
- コレクション（障害者向け資料：レベル1）
- コレクション（個別）
- 国立国会図書館デジタルコレクション > 電子書籍・電子雑誌 > 学術機関 > 学協会
- 収集根拠
- オンライン資料収集制度
- 受理日（W3CDTF）
- 2019-08-28T20:45:13+09:00
- 保存日（W3CDTF）
- 2019-03-13
- 記録形式（IMT）
- application/pdf
- オンライン閲覧公開範囲
- 国立国会図書館内限定公開
- デジタル化資料送信
- 図書館・個人送信対象外
- 遠隔複写可否（NDL）
- 可
- 掲載誌（国立国会図書館永続的識別子）
- info:ndljp/pid/11343755
- 連携機関・データベース
- 国立国会図書館 : 国立国会図書館デジタルコレクション
- コレクション（個別）
- 国立国会図書館デジタルコレクション > 電子書籍・電子雑誌 > 学術機関 > 学協会
- オンライン閲覧公開範囲
- 国立国会図書館内限定公開
- デジタル化資料送信
- 図書館・個人送信対象外
- 遠隔複写可否（NDL）
- 可
- 所蔵機関
- 国立国会図書館
- 請求記号
- Z53-B35
- 関連情報（国立国会図書館永続的識別子）
- info:ndljp/pid/11343758
- 連携機関・データベース
- 国立国会図書館 : 国立国会図書館雑誌記事索引
- 書誌ID（NDLBibID）
- 028879124
- 整理区分コード
- 632
- 要約等
- <p>Recent advances in genome databases have allowed discovery of novel classes of natural products and their biosynthetic enzymes. Given the potentials and advantages of the biosynthetic enzymes, they are applicable to not only the production of natural products but also synthesis and discovery of artificial molecules with desired functions. This account describes our recent efforts to develop artificial <i>in vitro</i> biosynthesis systems that potentially allow for the elaboration of pseudo-natural peptides with novel bioactivities.</p>
- DOI
- 10.1246/bcsj.20170379
- オンライン閲覧公開範囲
- インターネット公開
- 連携機関・データベース
- 科学技術振興機構 : J-STAGE
- 要約等
- <p>Recent advances in genome databases have allowed discovery of novel classes of natural products and their biosynthetic enzymes. Given the potentials and advantages of the biosynthetic enzymes, they are applicable to not only the production of natural products but also synthesis and discovery of artificial molecules with desired functions. This account describes our recent efforts to develop artificial <i>in vitro</i> biosynthesis systems that potentially allow for the elaboration of pseudo-natural peptides with novel bioactivities.</p>
- DOI
- 10.1246/bcsj.20170379
- オンライン閲覧公開範囲
- インターネット公開
- 関連情報（URI）
- 参照
- The RaPID Platform for the Discovery of Pseudo-Natural Macrocyclic PeptidesMethodologies for Backbone Macrocyclic Peptide Synthesis Compatible With Screening TechnologiesSoft material nanoarchitectonics at interfaces: molecular assembly, nanomaterial synthesis, and life controlIn Vitro Biosynthesis of Peptides Containing Exotic Azoline Analogues
- 参照
- Flexizymes for genetic code reprogrammingRibosomal Synthesis of Backbone‐Macrocyclic Peptides Containing γ‐Amino AcidsA Fluorescent Imaging Probe Based on a Macrocyclic Scaffold That Binds to Cellular EpCAMReprogramming the genetic code in vitroEfficient siRNA Delivery by Lipid Nanoparticles Modified with a Nonstandard Macrocyclic Peptide for EpCAM-TargetingHighly selective inhibition of histone demethylases by de novo macrocyclic peptidesIn vitro evolution of single-chain antibodies using mRNA displayRibosomal synthesis of dehydrobutyrine- and methyllanthionine-containing peptidesThiazole/oxazole-modified microcins: complex natural products from ribosomal templatesDereplication, sequencing and identification of peptidic natural products: from genome mining to peptidogenomics to spectral networksConstraining Cyclic Peptides To Mimic Protein Structure MotifsExpanding the amino acid repertoire of ribosomal polypeptide synthesis via the artificial division of codon boxesRecent Developments of Engineered Translational Machineries for the Incorporation of Non-Canonical Amino Acids into PolypeptidesNonstandard Peptide Expression under the Genetic Code Consisting of Reprogrammed Dual Sense CodonsReevaluation of the <scp>d</scp>-Amino Acid Compatibility with the Elongation Event in TranslationPharmacophore Generation from a Drug-like Core Molecule Surrounded by a Library Peptide via the 10BASEd-T on Bacteriophage T7Acetyl-lysine Analog Peptides as Mechanistic Probes of Protein DeacetylasesIncorporation of non-natural amino acids into proteinsExpanded Genetic Code Technologies for Incorporating Modified Lysine at Multiple SitesFlexizymes as a tRNA Acylation Tool Facilitating Genetic Code ReprogrammingSelection-based discovery of macrocyclic peptides for the next generation therapeuticsStructural Basis for Potent Inhibition of SIRT2 Deacetylase by a Macrocyclic Peptide Inducing Dynamic Structural ChangeRibosomal Synthesis of Peptides with Multiple β-Amino AcidsRibosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclatureDissection of goadsporin biosynthesis by in vitro reconstitution leading to designer analogues expressed in vivoSelective thioether macrocyclization of peptides having the N-terminal 2-chloroacetyl group and competing two or three cysteine residues in translationPhage Selection of Bicyclic Peptides Based on Two Disulfide Bridges<i>In vitro</i>selection and evolution of functional proteins by using ribosome displayNonproteinogenic Amino Acid Building Blocks for Nonribosomal Peptide and Hybrid Polyketide ScaffoldsYcaO-Dependent Posttranslational Amide Activation: Biosynthesis, Structure, and FunctionChapter 10 The Protein Synthetic Machinery: Ribosomes and Cell-Free SystemsDiscovery of Macrocyclic Peptides Armed with a Mechanism‐Based Warhead: Isoform‐Selective Inhibition of Human Deacetylase SIRT2Natural Product-Like Macrocyclic N-Methyl-Peptide Inhibitors against a Ubiquitin Ligase Uncovered from a Ribosome-Expressed De Novo LibrarySelection-Based Discovery of Druglike Macrocyclic PeptidesRibosomal synthesis of backbone macrocyclic peptidesEpCAM: A New Therapeutic Target for an Old Cancer AntigenExpanding and Reprogramming the Genetic Code of Cells and AnimalsRibosomal Synthesis of Cyclic Peptides with a Fluorogenic Oxidative Coupling ReactionDiversification of echinomycin molecular structure by way of chemoenzymatic synthesis and heterologous expression of the engineered echinomycin biosynthetic pathwayRNA-peptide fusions for the <i>in vitro</i> selection of peptides and proteinsOne-Pot Synthesis of Azoline-Containing Peptides in a Cell-free Translation System Integrated with a Posttranslational CyclodehydrataseBiological effects of cyclosporin A: A new antilymphocytic agentRibosomal Synthesis of Peptidase-Resistant Peptides Closed by a Nonreducible Inter-Side-Chain BondMechanism-based Modulator Discovery for Sirtuin-catalyzed Deacetylation ReactionAdding New Chemistries to the Genetic CodeInitiating translation with <i>D</i> -amino acidsRecent advances in engineering nonribosomal peptide assembly linesInvestigating the role of a backbone to substrate hydrogen bond in OMP decarboxylase using a site-specific amide to ester substitutionBlurring the Lines between Ribosomal and Nonribosomal Peptide ScaffoldsPatellamide A and C biosynthesis by a microcin-like pathway in <i>Prochloron didemni</i> , the cyanobacterial symbiont of <i>Lissoclinum patella</i>Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organellesOrally Absorbed Cyclic PeptidesCombinatorial Biosynthesis of Cyclic Lipopeptide Antibiotics: A Model for Synthetic Biology To Accelerate the Evolution of Secondary Metabolite Biosynthetic PathwaysCloning and characterization of the goadsporin biosynthetic gene cluster from Streptomyces sp. TP-A0584A global assembly line for cyanobactinsRibosomal Synthesis of Peptides with C‐Terminal Lactams, Thiolactones, and AlkylamidesTranslation Initiation with Initiator tRNA Charged with Exotic PeptidesNatural combinatorial peptide libraries in cyanobacterial symbionts of marine ascidiansA highly flexible tRNA acylation method for non-natural polypeptide synthesisFlexizymes, Their Evolutionary History and Diverse UtilitiesHistone demethylation by a family of JmjC domain-containing proteinsCell-free translation reconstituted with purified componentsThe evolution of genome mining in microbes – a reviewDiscovery of a widely distributed toxin biosynthetic gene clusterThe Biochemistry of SirtuinsNew tools for reconstruction and heterologous expression of natural product biosynthetic gene clustersIn vitro virus: Bonding of mRNA bearing puromycin at the 3′‐terminal end to the C‐terminal end of its encoded protein on the ribosome in vitroRibosomal peptide natural products: bridging the ribosomal and nonribosomal worldsPhage antibodies: filamentous phage displaying antibody variable domainsIn Vitro Reconstitution of Metabolic Pathways: Insights into Nature’s Chemical LogicReprogramming the Translation Initiation for the Synthesis of Physiologically Stable Cyclic PeptidesChemical Posttranslational Modification of Phage-Displayed PeptidesSelection and evolution of enzymes from a partially randomized non-catalytic scaffoldGoadsporin, a Chemical Substance which Promotes Secondary Metabolism and Morphogenesis in Streptomycetes. II. Structure Determination.Monooxygenation of Nonnative Substrates Catalyzed by Bacterial Cytochrome P450s Facilitated by Decoy MoleculesA post-translational cyclodehydratase, PatD, tolerates sequence variation in the C-terminal region of substrate peptides
- 連携機関・データベース
- 国立情報学研究所 : CiNii Research
- 提供元機関・データベース
- Japan Link Center雑誌記事索引データベース雑誌記事索引データベースCrossrefCiNii Articles科学研究費助成事業データベース科学研究費助成事業データベース科学研究費助成事業データベース科学研究費助成事業データベース科学研究費助成事業データベースCrossrefCrossrefCrossrefCrossref
- 書誌ID（NDLBibID）
- 02887912411343758
- NII論文ID
- 130006507065