並列タイトル等レビー小体型認知症における病前性格と認知症の行動・心理症状の関連：アルツハイマー型認知症と比較して
タイトル（掲載誌）Psychiatry and clinical neurosciences.
一般注記AIM:
The aim of this study was to elucidate the relation between premorbid personality traits and behavioral and psychological symptoms in dementia (BPSD) in dementia with Lewy bodies (DLB) and Alzheimer's disease (AD) patients.
METHODS:
Forty-one DLB patients and 98 AD patients were assessed for BPSD using the Neuropsychiatric Inventory (NPI). Each patient's midlife personality traits were rated by a family member using the NEO Five-Factor Inventory (NEO-FFI) questionnaire.
RESULTS:
In multiple regression analyses for DLB patients, NPI total score and anxiety were significantly associated with premorbid openness, delusion with premorbid agreeableness, and agitation with premorbid conscientiousness. In AD patients, depression was significantly associated with premorbid neuroticism, and agitation, apathy, and irritability with premorbid agreeableness.
CONCLUSION:
Premorbid personalities affected BPSD differently in DLB and AD. Given the differences in the effects of premorbid personalities on BPSD, additional studies are needed to develop interventions to reduce these symptoms.
identifier:PMID：28177178
開始ページ : 409
終了ページ : 416
DOIinfo:doi/10.1111/pcn.12511
コレクション（個別）国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文
受理日（W3CDTF）2019-11-04T14:30:53+09:00
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