The failure of two major formaldehyde catabolism enzymes (ADH5 and ALDH2) leads to partial synthetic lethality in C57BL/6 mice

• 資料種別: 記事
• タイトル: The failure of two major formaldehyde catabolism enzymes (ADH5 and ALDH2) leads to partial synthetic lethality in C57BL/6 mice
• 著者・編者: Jun Nakamura; Darcy W. Holley; Toshihiro Kawamoto
• 出版事項: 日本 : Springer Nature
• 出版年月日等: 2020-06-03
• 出版年（W3CDTF）: 2020-06-03
• タイトル（掲載誌）: Genes and environment
• 巻号年月日等（掲載誌）: 42(21)
• 掲載巻: 42(21)
• ISSN（掲載誌）: 1880-7062
• ISSN-L（掲載誌）: 1880-7046
• 本文の言語コード: eng
• DOI: 10.1186/s41021-020-00160-4; https://doi.org/10.1186/s41021-020-00160-4
• 国立国会図書館永続的識別子: info:ndljp/pid/11520477; https://dl.ndl.go.jp/pid/11520477
• コレクション（共通）: 障害者向け資料
• コレクション（障害者向け資料：レベル1）: テキストデータ
• コレクション（個別）: 国立国会図書館デジタルコレクション > 電子書籍・電子雑誌 > その他; https://dl.ndl.go.jp/collections/B00035
• 収集根拠: オンライン資料収集制度
• 受理日（W3CDTF）: 2020-08-03T12:00:21+09:00
• 保存日（W3CDTF）: 2020-08-03
• 記録形式（IMT）: application/pdf
• オンライン閲覧公開範囲: 国立国会図書館内限定公開
• デジタル化資料送信: 図書館・個人送信対象外
• 遠隔複写可否（NDL）: 可
• 掲載誌（URI）: https://genesenvironment.biomedcentral.com/articles
• 掲載誌（国立国会図書館永続的識別子）: info:ndljp/pid/11467640; https://dl.ndl.go.jp/pid/11467640
• 連携機関・データベース: 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

• 要約等: コレクション : 国立国会図書館デジタルコレクション > 電子書籍・電子雑誌 > その他
• DOI: 10.1186/s41021-020-00160-4; https://doi.org/10.1186/s41021-020-00160-4
• オンライン閲覧公開範囲: インターネット公開
• 関連情報（URI）: http://id.ndl.go.jp/digimeta/11520477; https://dl.ndl.go.jp/pid/11520477; https://link.springer.com/content/pdf/10.1186/s41021-020-00160-4.pdf; https://link.springer.com/article/10.1186/s41021-020-00160-4/fulltext.html; https://search.jamas.or.jp/link/ui/2021150902
• 参照: Fanconi anemia and Aldehyde Degradation Deficiency Syndrome: Metabolism and DNA repair protect the genome and hematopoiesis from endogenous DNA damage; https://cir.nii.ac.jp/crid/1050016494530920960; ALDH2 polymorphism rs671 is a predictor of PD-1/PD-L1 inhibitor efficacy against thoracic malignancies; https://cir.nii.ac.jp/crid/1360294643836841216; Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia–like IBMFS <i>ADH5/ALDH2</i> deficiency; https://cir.nii.ac.jp/crid/1360572092665305344; Potential Doxorubicin-Mediated Dual-Targeting Chemotherapy in FANC/BRCA-Deficient Tumors via Modulation of Cellular Formaldehyde Concentration; https://cir.nii.ac.jp/crid/1360853567343512960
• 参照: Variant ALDH2 is associated with accelerated progression of bone marrow failure in Japanese Fanconi anemia patients; https://cir.nii.ac.jp/crid/1050564285731241216; Kinetic Mechanism of Human Glutathione-Dependent Formaldehyde Dehydrogenase; https://cir.nii.ac.jp/crid/1360011145905851264; Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway; https://cir.nii.ac.jp/crid/1360283691794252928; DNA-protein crosslink formation by endogenous aldehydes and AP sites; https://cir.nii.ac.jp/crid/1360290617389805312; Endogenous formaldehyde is a memory-related molecule in mice and humans; https://cir.nii.ac.jp/crid/1360292619952185344; The formaldehyde metabolic detoxification enzyme systems and molecular cytotoxic mechanism in isolated rat hepatocytes; https://cir.nii.ac.jp/crid/1360292620094165888; Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function; https://cir.nii.ac.jp/crid/1360292620871115776; Substrate specificity of human and yeast aldehyde dehydrogenases; https://cir.nii.ac.jp/crid/1360574095113977856; Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily; https://cir.nii.ac.jp/crid/1360574095464967680; Cells Deficient in the FANC/BRCA Pathway Are Hypersensitive to Plasma Levels of Formaldehyde; https://cir.nii.ac.jp/crid/1360574095879974016; FHR5 Binds to Laminins, Uses Separate C3b and Surface-Binding Sites, and Activates Complement on Malondialdehyde-Acetaldehyde Surfaces; https://cir.nii.ac.jp/crid/1360855568652972928; Aldehyde dehydrogenase (ALDH) 2 associates with oxidation of methoxyacetaldehyde; in vitro analysis with liver subcellular fraction derived from human and <i>Aldh2</i> gene targeting mouse; https://cir.nii.ac.jp/crid/1361137045654290816; The association of mitochondrial aldehyde dehydrogenase gene (ALDH2) polymorphism with susceptibility to late-onset Alzheimer's disease in Chinese; https://cir.nii.ac.jp/crid/1361418518486398080; Kinetics of Cytochrome P450 2E1-Catalyzed Oxidation of Ethanol to Acetic Acid via Acetaldehyde; https://cir.nii.ac.jp/crid/1361699994482186496; Evidence that endogenous formaldehyde produces immunogenic and atherogenic adduct epitopes; https://cir.nii.ac.jp/crid/1361981470489018624; Deficiency in Mitochondrial Aldehyde Dehydrogenase Increases the Risk for Late-Onset Alzheimer's Disease in the Japanese Population; https://cir.nii.ac.jp/crid/1361981471280958080; Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism; https://cir.nii.ac.jp/crid/1361981471311131904; Toxicological and Metabolic Consequences of Methanol Poisoning; https://cir.nii.ac.jp/crid/1362262943610674816; ALDH2 polymorphisms and bone mineral density in an elderly Japanese population; https://cir.nii.ac.jp/crid/1362262944185879936; Formaldehyde Dehydrogenase from Human Liver; https://cir.nii.ac.jp/crid/1362544419616286592; Active DNA demethylation: many roads lead to Rome; https://cir.nii.ac.jp/crid/1362544421186567168; Endogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen; https://cir.nii.ac.jp/crid/1362544421249510144; A Novel Mechanism for Endogenous Formaldehyde Elevation in SAMP8 Mouse; https://cir.nii.ac.jp/crid/1362544421276748416; Lymphocyte Development Requires <i>S</i>-nitrosoglutathione Reductase; https://cir.nii.ac.jp/crid/1362825894298665216; The Janus face of alcohol dehydrogenase 3; https://cir.nii.ac.jp/crid/1363388843703796864; Reduction of <i>S</i>-nitrosoglutathione by alcohol dehydrogenase 3 is facilitated by substrate alcohols via direct cofactor recycling and leads to GSH-controlled formation of glutathione transferase inhibitors; https://cir.nii.ac.jp/crid/1363670318227848576; Oxidation-specific epitopes restrain bone formation; https://cir.nii.ac.jp/crid/1363951793765784320; Effects of Aldehyde Dehydrogenase-2 Genetic Polymorphisms on Metabolism of Structurally Different Aldehydes in Human Liver; https://cir.nii.ac.jp/crid/1364233270355947776; Acid-specific formaldehyde donor is a potential, dual targeting cancer chemotherapeutic/chemo preventive drug for FANC/BRCA-mutant cancer; https://cir.nii.ac.jp/crid/2050588892094259456
• 連携機関・データベース: 国立情報学研究所 : CiNii Research; https://cir.nii.ac.jp/
• 提供元機関・データベース: 雑誌記事索引データベース; https://ndlsearch.ndl.go.jp; Crossref; https://www.crossref.org; 科学研究費助成事業データベース; https://kaken.nii.ac.jp/ja
• 書誌ID（NDLBibID）: 11520477; http://id.ndl.go.jp/bib/11520477