Analysis of fracture healing process by HR-pQCT in patients with distal radius fracture

• 資料種別: 博士論文
• ISSN: 0914-8779
• タイトル: Analysis of fracture healing process by HR-pQCT in patients with distal radius fracture
• 巻次・部編番号: 38 5
• 著者・編者: 西野, 雄一朗
• 著者標目: 西野, 雄一朗
• 出版事項: Springer Japan
• 出版年月日等: 2020-09-02
• 出版年（W3CDTF）: 2020-09-02
• 並列タイトル等: HR-pQCTによる橈骨遠位端骨折の治癒過程の解析
• タイトル（掲載誌）: Journal of Bone and Mineral Metabolism
• 授与機関名: Nagasaki University (長崎大学)
• 授与年月日: 2020-09-02
• 授与年月日（W3CDTF）: 2020-09-02
• 報告番号: 甲医歯薬第1271号
• 学位: 博士(医学)
• 博論授与番号: 甲医歯薬第1271号
• 本文の言語コード: eng
• 件名標目: Fracture healing; High-resolution peripheral quantitative computed tomography (HR-pQCT); Distal radius fracture
• 対象利用者: 一般
• 一般注記: Introduction: High-resolution peripheral quantitative computed tomography (HR-pQCT) has enabled us to observe the changes in bone microarchitecture over time in vivo. In this study, the process of fracture healing was analyzed using HR-pQCT in patients with distal radius fracture who underwent osteosynthesis. Materials and methods: A total of 10 fracture sites identified from four patients with a distal radius fracture who underwent internal fixation with a volar locking plate (mean age 68.8 years, all women) were investigated. HR-pQCT was performed within a week (baseline) 4, 12, and 24 weeks after fracture. Rectangular region of interest (ROI) was established in the fracture site, inner callus, and external callus area, and the changes in bone mineral density (BMD) in each region were analyzed. Results: From baseline to 24 weeks post-fracture, the BMD changed from 105.5 (95% CI 98.6?113) to 428.0 (331?554) mgHA/ccm at the fracture site, from 111.0 (104?119) to 375.3 (290?486) mgHA/ccm at the inner callus area, and from 98.5 (91.6?106) to 171.6 (132?222) mgHA/ccm at the external callus area. The BMD increased at the fracture site and inner callus area, but increased only slightly at the external callus area. At 24 weeks post-fracture, the BMD at the fracture site and inner callus area was significantly higher than the external callus area. Conclusion In the healing process of postoperative distal radius fractures, increased BMD at the inner surface of the fracture site was confirmed in all fractures. Bone formation on the endosteal side may be a necessary condition for bone union of distal radius fractures.; 長崎大学学位論文 学位記番号:博(医歯薬)甲第1271号 学位授与年月日:令和2年9月2日; Author: Yuichiro Nishino, Ko Chiba, Makoto Era, Narihiro Okazaki, Takashi Miyamoto, Akihiko Yonekura, Masato Tomita & Makoto Osaki; Citation: Journal of Bone and Mineral Metabolism, 38(5), pp.710-717; 2020; identifier:Nagasaki University (長崎大学), 博士(医学) (2020-09-02); http://hdl.handle.net/10069/40341
• DOI: info:doi/10.1007/s00774-020-01109-x; https://doi.org/info:doi/10.1007/s00774-020-01109-x
• 国立国会図書館永続的識別子: info:ndljp/pid/11678946; https://dl.ndl.go.jp/pid/11678946
• コレクション（共通）: 障害者向け資料
• コレクション（障害者向け資料：レベル1）: テキストデータ
• コレクション（個別）: 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• 収集根拠: 博士論文（自動収集）
• 受理日（W3CDTF）: 2021-06-07T02:06:26+09:00
• 作成日（W3CDTF）: 2020-12-16
• 記録形式（IMT）: PDF
• オンライン閲覧公開範囲: 国立国会図書館内限定公開
• デジタル化資料送信: 図書館・個人送信対象外
• 遠隔複写可否（NDL）: 可
• 関連情報（URI）: http://hdl.handle.net/10069/40341
• 掲載誌（URI）: http://hdl.handle.net/10069/40278
• 連携機関・データベース: 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp