Optimal plane selection for measuring post-prandial blood flow increase within the superior mesenteric artery: Analysis using 4D flow and computational fluid dynamics 4

• 資料種別: 博士論文
• ISSN: 1347-3182
• タイトル: Optimal plane selection for measuring post-prandial blood flow increase within the superior mesenteric artery: Analysis using 4D flow and computational fluid dynamics
• 巻次・部編番号: 19 4
• 著者・編者: 杉山, 将隆
• 著者標目: 杉山, 将隆
• 出版事項: Japanese Society for Magnetic Resonance in Medicine
• 出版年月日等: 2020
• 出版年（W3CDTF）: 2020
• 並列タイトル等: 食事負荷後の上腸間膜動脈の血流増加を測定するのに最適な断面の選択: 4D Flowと計算流体力学を用いた解析
• タイトル（掲載誌）: Magnetic Resonance in Medical Sciences
• 授与機関名: 浜松医科大学
• 授与年月日: 2020-10-16
• 授与年月日（W3CDTF）: 2020-10-16
• 報告番号: 甲第847号
• 学位: 博士（医学）
• 博論授与番号: 甲第847号
• 本文の言語コード: eng
• 件名標目: 4D Flow; phase contrast image; superior mesenteric artery; flow measurement; post-prandial hyperemia
• 対象利用者: 一般
• 一般注記: doctoral; 医学系研究科; Purpose: 2D cine phase contrast (PC)-MRI is a standard velocimetry for the superior mesenteric artery (SMA); however, the optimal localization of the measurement plane has never been fully discussed previously. The purpose of this Institutional Review Board approved prospective and single arm study is to test whether flow velocimetry of the SMA with combined use of 2D cine PC-MRI and meal challenge is dependent on the localizations of the measurement planes and to seek optimal section for velocimetry.Methods: Seven healthy volunteers underwent cardiac phase resolved ECG gated 2D cine PC-MRI pre- and 30 min post-meal challenge at three measurement planes: proximal, curved mid section and distal straight section of the SMA at 3T. 4D Flow using 3D cine PC-MRI with vastly undersampled isotropic projection imaging (PC VIPR) was also performed right after 2D cine PC-MRI to delineate the flow dynamics within the SMA using streamline analysis. Two radiologists measured flow velocities, and rated the appearances of the abnormal flow in the SMA on streamlines derived from the 4D Flow and the computational fluid dynamics (CFD).Results: 2D cine PC-MRI measured increased temporally averaged flow velocity (mm/s) after the meal challenge only in the proximal (129.3 vs. 97.8, P=0.0313) and distal section (166.9 vs. 96.2, P=0.0313), not in the curved mid section (113.1 vs. 85.5, P=0.0625). The average velocities were highest and their standard errors (8.5?26.5) were smallest at the distal straight section both before and after the meal challenge as compared with other sections. The streamline analysis depicted more frequent appearances of vertical or helical flow in the curved mid section both on 4D Flow and CFD (κ: 0.27?0.68).Conclusion: SMA velocimetry with 2D cine PC-MRI was dependent on the localization of the measurement planes. Distal straight section, not in the curved mid section is recommended for MR velocimetry.
• DOI: info:doi/10.2463/mrms.mp.2019-0089; https://doi.org/info:doi/10.2463/mrms.mp.2019-0089
• 国立国会図書館永続的識別子: info:ndljp/pid/11679132; https://dl.ndl.go.jp/pid/11679132
• コレクション（共通）: 障害者向け資料
• コレクション（障害者向け資料：レベル1）: テキストデータ
• コレクション（個別）: 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• 収集根拠: 博士論文（自動収集）
• 受理日（W3CDTF）: 2021-06-07T02:06:26+09:00
• 作成日（W3CDTF）: 2021-05-06
• 記録形式（IMT）: application/pdf
• オンライン閲覧公開範囲: 国立国会図書館内限定公開
• デジタル化資料送信: 図書館・個人送信対象外
• 遠隔複写可否（NDL）: 可
• 掲載誌（URI）: http://hdl.handle.net/10271/00003854; https://hama-med.repo.nii.ac.jp/records/3725
• 連携機関・データベース: 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp