並列タイトル等アロマ吸引によるラット顎下腺唾液の抗菌タンパク質分泌促進効果
一般注記Application of aroma inhalation is likely to enhance antimicrobial action. We studied the influence of sympathetic nerve stimulation and aroma inhalation on both SIgA and lactoferrin secretion in the rat submandibular gland. We found no spontaneous secretion from the submandibular gland in the control rats. Although the flow of the saliva evoked by black pepper and cardamom was very small in volume, a marked saliva secretion was found evoked when isoprenaline stimulation was combined with black pepper or cardamom inhalation. Significant secretion of SIgA and lactoferrin was not obtained with black pepper or cardamon inhalation alone. However, there was considerable secretion of SIgA and lactoferrin induced when isoprenaline stimulation was combined with black pepper inhalation.The salivary amylase activity induced by aroma inhalation was approximately 10% that of isoprenaline stimulation alone. Combined use of the two enhanced salivary amylase activity compared with stimulation by isoprenaline alone. Their combined use had a synergistic effect. These results suggest that the use of aroma inhalation enhances salivary antibacterial activity, and that this activity may be induced by the sympathetic nervous system. In addition, aroma inhalation imparts a greater effect on SIgA and lactoferrin secretion than does solitary sympathetic stimulation alone. We hypothesized that aroma inhalation might positively influence the intraoral environment.
2017年度
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