並列タイトル等骨欠損に大きさの異なるβ- TCP 顆粒を填入したときの顆粒間隙の計測 －実験動物と骨欠損モデルとの比較－
一般注記We investigated the granule interspaces created for vascular formation when a bone defect is filled with four sizes of β-TCP granules. Bone defects in experimental animals and models were filled with the granules. Images were obtained from the samples using micro-CT imaging, and the average volume of the granule interspaces was measured by 3D image analysis software. When a bone defect was filledwith granules, the larger granules created lager interspaces. It is thought that maintenance of the granule interspaces when filling the defect may favor microvascular development and new bone formation. Therefore, we speculated that granule resorption might be faster with a smaller granule size. However, it is also thought that smaller interspaces might lead to less microvascular formation, further delaying new bone formation.
2015
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