並列タイトル等骨欠損に大きさの異なるβ—TCP顆粒を填入したときの顆粒間隙と新生血管形成
一般注記We investigated how granule interspaces affected vascular formation when a bone defect is filled with different sizes of β-TCP granules. Bone defects in the experimental animals were filled with four sizes of β-TCP granules. Bone and microvascular corrosion cast specimens were then prepared for SEM, and the volume of the newly-formed vascular network was calculated from the SEM images. Newly-formed vasculature was observed in the granule interspaces with all sizes of granules. In particular, the newly-formed vasculature in smaller granules was uniformly distributed. The volume of the newly-formed vasculature was approximately equal in both the experimental and control animals. When β-TCP granules were used to fill bone defects, newly-formed vessels were more uniformly distributed in defects filled with small granules, which are considered advantageous for microvascular formation.
2015
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