Efficacy of autogenous bone grafts preserved in 80% ethanol solution for preventing surgical site infection after cranioplasty: A retrospective cohort study.

• 資料種別: 博士論文
• ISSN: 2214-7519
• タイトル: Efficacy of autogenous bone grafts preserved in 80% ethanol solution for preventing surgical site infection after cranioplasty: A retrospective cohort study.
• 巻次・部編番号: 28
• 著者・編者: Kogeichi, Yohei; Motoyama, Yasushi; Takeshima, Yasuhiro; Matsuda, Ryosuke; Tamura, Kentaro; Nishimura, Fumihiko; Yamada, Shuichi; Nakagawa, Ichiro; Park, Young-Su; Fukushima, Hidetada; Nakase, Hiroyuki
• 著者標目: Kogeichi, Yohei; Motoyama, Yasushi; Takeshima, Yasuhiro; Matsuda, Ryosuke; Tamura, Kentaro; Nishimura, Fumihiko; Yamada, Shuichi; Nakagawa, Ichiro; Park, Young-Su; Fukushima, Hidetada; Nakase, Hiroyuki
• 出版事項: Elsevier
• 出版年月日等: 2022-06; 28
• 出版年（W3CDTF）: 2022-06
• 並列タイトル等: 頭蓋骨形成術後の手術部位感染予防のための80％エタノール溶液に保存した自家骨移植片の有効性。後方視的コホート研究
• タイトル（掲載誌）: Interdisciplinary neurosurgery
• 授与機関名: 奈良県立医科大学
• 授与年月日: 2022-03-15
• 授与年月日（W3CDTF）: 2022-03-15
• 報告番号: 乙第1526号
• 学位: 博士（医学）
• 博論授与番号: 乙第1526号
• 本文の言語コード: eng
• 件名標目: Autogenous bone graft; Decompressive craniectomy; Ethanol; Surgical site infection
• 対象利用者: 一般
• 一般注記: type:Thesis; Background: Surgical site infection (SSI) is common following cranioplasty after decompressive craniectomy (DC). The aim of this study was to assess the risk of SSI following cranioplasty in terms of the preservation method of autogenous bone graft (ABG), comparing preservation in 80% ethanol versus the standard method of subcutaneous ABG preservation. Material and methods: The patients who underwent cranioplasty using ABGs after DC between 2008 and 2019 were retrospectively reviewed. SSIs were compared between patients whose ABG was preserved in 80% ethanol (group A) and those whose ABG was preserved subcutaneously (group B) using inverse probability of treatment weighting (IPTW) based on propensity scores to balance measurable confounders including elderly age, sex, expanded polytetrafluoroethylene, stroke, interval to cranioplasty, and diabetes mellitus. Results: Total number of 127 patients consisted of 56 in group A and 71 in group B. SSI after cranioplasty occurred in five patients each in groups A and B (8.9% vs. 7%, p = 0.748). IPTW analysis demonstrated that preservation in 80% ethanol was associated with a lower risk of SSI (odds ratio: 0.239, 95％ confidence interval: 0.0615–0.927, p = 0.039). Conclusion: The simple and less-invasive method of preserving ABGs in 80% ethanol for cranioplasty after DC might be potentially safe from an SSI perspective.; 博士（医学）・乙第1526号・令和4年3月15日; © 2022 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND licens(https://creativecommons.org/licenses/by-nc-nd/4.0/).; identifier:Interdisciplinary neurosurgery Vol.28 Article No.101489 (2022 Jun); identifier:22147519; identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/4031; identifier:Interdisciplinary neurosurgery, 28: Article No.101489
• DOI: info:doi/10.1016/j.inat.2022.101489; https://doi.org/info:doi/10.1016/j.inat.2022.101489
• 国立国会図書館永続的識別子: info:ndljp/pid/12304454; https://dl.ndl.go.jp/pid/12304454
• コレクション（共通）: 障害者向け資料
• コレクション（障害者向け資料：レベル1）: テキストデータ
• コレクション（個別）: 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• 収集根拠: 博士論文（自動収集）
• 受理日（W3CDTF）: 2022-07-05T02:30:21+09:00
• 記録形式（IMT）: PDF; application/pdf
• オンライン閲覧公開範囲: 国立国会図書館内限定公開
• デジタル化資料送信: 図書館・個人送信対象外
• 遠隔複写可否（NDL）: 可
• 掲載誌（URI）: http://hdl.handle.net/10564/4031
• 連携機関・データベース: 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp

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