A case of hypertensive disorders of pregnancy that developed at 9 weeks of gestation
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- 資料種別
- 記事
- 著者・編者
- Saki HayashiNaro OhashiDaiki Goto
- 出版年月日等
- 2021-03-15
- 出版年（W3CDTF）
- 2021-03-15
- タイトル（掲載誌）
- CEN case reports
- 巻号年月日等（掲載誌）
- 10(4)
- 掲載巻
- 10(4)
- ISSN（掲載誌）
- 2192-4449
- 本文の言語コード
- eng
- DOI
- 10.1007/s13730-021-00592-z
- 国立国会図書館永続的識別子
- info:ndljp/pid/12312836
- コレクション（共通）
- コレクション（障害者向け資料：レベル1）
- コレクション（個別）
- 国立国会図書館デジタルコレクション > 電子書籍・電子雑誌 > その他
- 収集根拠
- オンライン資料収集制度
- 受理日（W3CDTF）
- 2022-08-04T20:17:49+09:00
- 保存日（W3CDTF）
- 2022-07-22
- 記録形式（IMT）
- application/pdf
- オンライン閲覧公開範囲
- 国立国会図書館内限定公開
- デジタル化資料送信
- 図書館・個人送信対象外
- 遠隔複写可否（NDL）
- 可
- 掲載誌（国立国会図書館永続的識別子）
- info:ndljp/pid/12312832
- 連携機関・データベース
- 国立国会図書館 : 国立国会図書館デジタルコレクション
- 要約等
- application/pdfPreeclampsia and superimposed preeclampsia usually develop after 20 weeks of gestation. We report a case of a 35-year-old Japanese woman who developed hypertensive disorders of pregnancy (HDP) before 20 weeks of gestation. She presented with hypertension and proteinuria at 9 and 11 weeks of gestation, respectively, and developed nephrotic syndrome at 17 weeks of gestation. She did not have definite hypertension or urinary abnormalities before pregnancy. The patient was serologically positive for the antinuclear antibody. However, the complement levels were normal and anti-phospholipid antibody was not detected. A renal biopsy performed at 18 weeks of gestation showed diffuse endotheliosis and tip lesions of secondary focal segmental glomerulosclerosis but no hypertensive changes of the arterioles. Although electron microscopic examination showed electron-dense deposits in the subendothelial lesions, they were considered nonspecific plasma exudation by mass spectrometry. An abortion was performed at 20 weeks gestation because the patient’s congestive symptoms due to nephrotic syndrome had worsened and marked fetal growth restriction was observed. After delivery, the patient’s symptoms resolved immediately without any additional treatment; however, continuous antihypertensive medication was required. Finally, the patient was diagnosed with HDP based on the renal biopsy findings and her clinical course after delivery. Compared to previous reports, this case describes the earliest onset of HDP. Thus, HDP should be considered as a differential diagnosis in pregnant women with hypertension or proteinuria presenting with symptoms before 20 weeks of gestation.
- DOI
- 10.1007/s13730-021-00592-z
- 著作権情報
- This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s13730-021-00592-z
- 関連情報（URI）
- 参照
- Impaired autophagy by soluble endoglin, under physiological hypoxia in early pregnant period, is involved in poor placentation in preeclampsiaPredictive Value of the sFlt-1:PlGF Ratio in Women with Suspected PreeclampsiaThe Intrarenal Vascular Lesions Associated with Primary Antiphospholipid SyndromeObstetrical outcome and treatments in seronegative primary APS: data from European retrospective studyProportion of peripheral blood and decidual CD4+ CD25bright regulatory T cells in pre-eclampsiaPreeclampsia: A close look at renal dysfunctionPregnancy-Associated Hemolytic Uremic Syndrome Revisited in the Era of Complement Gene MutationsThe Glomerular Injury of PreeclampsiaEmbryo cryopreservation and preeclampsia risk‘Pure’ pre‐eclampsia before 20 weeks of gestation: a unique entityRisks of hypertensive disorders in the second pregnancyNon-conventional antiphospholipid antibodies in patients with clinical obstetrical APS: Prevalence and treatment efficacy in pregnanciesThe prognosis of pregnancy in women with chronic hypertensionComplement activation in patients with primary antiphospholipid syndromeInadequate tolerance induction may induce pre-eclampsiaHypertension in pregnancy.Acute Fatty Liver Disease of Pregnancy: Updates in Pathogenesis, Diagnosis, and ManagementBalance of antiangiogenic and angiogenic factors in the context of the etiology of preeclampsiaAssisted reproductive technology and the risk of pregnancy-related complications and adverse pregnancy outcomes in singleton pregnancies: a meta-analysis of cohort studiesSeronegative antiphospholipid syndrome: refining the value of “non-criteria” antibodies for diagnosis and clinical managementRemoval of Soluble Fms-Like Tyrosine Kinase-1 by Dextran Sulfate Apheresis in PreeclampsiaA Case of “Pure” Preeclampsia With Nephrotic Syndrome Before 15 Weeks of Gestation in a Patient Whose Renal Biopsy Showed Glomerular Capillary EndotheliosisCirculating Angiogenic Factors and the Risk of PreeclampsiaHypertension and Proteinuria in a 17-Year-Old at 19 Weeks’ GestationNew definition and classification of “Hypertensive Disorders of Pregnancy (HDP)Preeclampsia before 20 weeks of gestation : a case report and review of the literature
- 連携機関・データベース
- 国立情報学研究所 : CiNii Research
- 提供元機関・データベース
- 学術機関リポジトリデータベース雑誌記事索引データベースCrossref科学研究費助成事業データベース学術機関リポジトリデータベース学術機関リポジトリデータベース
- 書誌ID（NDLBibID）
- 12312836