Comparison of calcium and hydroxyl ion release ability and in vivo apatite-forming ability of three bioceramic-containing root canal sealers

• 資料種別: 博士論文
• タイトル: Comparison of calcium and hydroxyl ion release ability and in vivo apatite-forming ability of three bioceramic-containing root canal sealers
• 著者・編者: Ibn Belal, Md Razi Saifullah
• 著者標目: Ibn Belal, Md Razi Saifullah
• 出版年月日等: 2022-03-23
• 出版年（W3CDTF）: 2022-03-23
• 並列タイトル等: 3種のバイオセラミック配合シーラーのカルシウム水酸化物イオン放出能および生体内アパタイト形成能の比較
• 授与機関名: 新潟大学
• 授与年月日: 2022-03-23
• 授与年月日（W3CDTF）: 2022-03-23
• 報告番号: 甲第5031号
• 学位: 博士（歯学）
• 博論授与番号: 甲第5031号
• 本文の言語コード: eng
• 件名標目: Bioceramic-containing root canal sealer; Apatite-forming ability; Calcium ion release; Hydroxyl ion release; Subcutaneous implantation; Electron probe microanalyzer
• 対象利用者: 一般
• 一般注記: Objective Bioceramic-containing root canal sealers promote periapical healing via Ca2+ and OH- release and apatite formation on the surface. This study aimed to compare Ca2+ and OH- release and in vivo apatite formation of three bioceramic-containing root canal sealers: EndoSequence BC sealer (Endo-BC), MTA Fillapex (MTA-F), and Nishika Canal Sealer BG (N-BG). Materials and methods Polytetrafuoroethylene tubes filled with sealers were immersed in distilled water for 6 and 12 h and for 1, 7, 14, and 28 days to measure Ca2+ and OH- release. Additionally, tubes filled with sealers were implanted in the backs of rats for 28 days, and in vivo apatite formation was analyzed using an electron probe microanalyzer. Results Endo-BC released significantly more Ca2+ than the other sealers at 6 and 12 h and 1 day. Ca2+ release was significantly lower from N-BG than from Endo-BC and MTA-F at 14 and 28 days. OH- release was significantly higher from Endo-BC than from the other sealers throughout the experiment, except at 1 day. OH- release was lower from N-BG than from MTA-F at 6 h and 7 days. Only Endo-BC implants exhibited apatite-like calcium-, phosphorus-, oxygen-, and carbon-rich spherulites and apatite layer-like calcium- and phosphorus-rich, but radiopaque element-free, surface regions. Conclusions Ca2+ and OH- release is ranked as follows: Endo-BC>MTA-F>N-BG. Only Endo-BC demonstrated in vivo apatite formation. Clinical relevance Endo-BC could promote faster periapical healing than MTA-F and N-BG.; Clinical Oral Investigations. 2022, 26(2), 1443-1451.; 新大院博(歯)第517号
• 国立国会図書館永続的識別子: info:ndljp/pid/12313591; https://dl.ndl.go.jp/pid/12313591
• コレクション（共通）: 障害者向け資料
• コレクション（障害者向け資料：レベル1）: テキストデータ
• コレクション（個別）: 国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文; https://dl.ndl.go.jp/collections/A00014
• 収集根拠: 博士論文（自動収集）
• 受理日（W3CDTF）: 2022-08-08T06:02:54+09:00
• 記録形式（IMT）: application/pdf
• オンライン閲覧公開範囲: 国立国会図書館内限定公開
• デジタル化資料送信: 図書館・個人送信対象外
• 遠隔複写可否（NDL）: 可
• 掲載誌（URI）: http://hdl.handle.net/10191/0002000647; https://niigata-u.repo.nii.ac.jp/records/2000647
• 連携機関・データベース: 国立国会図書館 : 国立国会図書館デジタルコレクション; https://dl.ndl.go.jp