一般注記Intestinal microflora plays a significant role in systemic health and immunity. However, oral microflora is still poorly understood and research is ongoing to identify substances that improve it. Propolis, a resinous substance found in beehives, is produced by honeybees by mixing plant shoots and resin with saliva and other enzymatic secretions. The natural antimicrobial properties of propolis from several regions such as Brazil, Mexico, Taiwan, and Okinawa have been previously reported. However, the anti-microbial property of Hawaiian propolis, which is from the same botanical source in subtropical regions such as Taiwan and Okinawa remains to be characterized. In this study, we investigated the antibacterial activities of Hawaiian propolis against Actinomyces oris (A. oris), early adherents of biofilm formation on the tooth surface, and against Porphyromonas gingivalis (P. gingivalis), a periodontopathic bacterium. We measured the inhibitory effect of ethanol-extracted propolis on the growth of A. oris and P. gingivalis and determined the minimum inhibitory concentration and minimum bactericidal concentration of ethanol-extracted propolis against these oral pathogen bacteria. Our results suggest that Hawaiian propolis is an effective antimicrobial against A. oris and P. gingivalis with implications for usage in aiding dental health.
2022年度
コレクション（個別）国立国会図書館デジタルコレクション > デジタル化資料 > 博士論文
受理日（W3CDTF）2022-11-07T16:56:35+09:00
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