並列タイトル等外側環軸関節の関節症性変化のリスク増加に関連する要因; 後ろ向き研究
一般注記type:Thesis
Purpose Atlantodens osteoarthritis and atlantoaxial osteoarthritis cause neck pain and suboccipital headaches. Currently,knowledge on the risk factors for atlantoaxial osteoarthritis is lacking. This study aimed to investigate the factors relatedto the increased risk of atlantoaxial osteoarthritis. Methods We analyzed computed tomography (CT) images of the uppercervical spine of 1266 adult trauma patients for whom upper cervical spine CT was performed at our hospital between 2014and 2019. The degree of atlantoaxial osteoarthritis was quantified as none-to-mild (not having osteoarthritis) or moderateto-severe (having osteoarthritis). Risk factors associated with atlantoaxial osteoarthritis were identified using univariate andmultivariable logistic regression analyses. Results The study group included 69.4% men, and the overall average age of thestudy population was 54.9 ± 20.4 years. The following factors were independently and significantly associated with atlantoaxialosteoarthritis in the multivariable logistic regression analysis: age in the sixth decade or older (odds ratio [OR], 20.5;95% confidence interval [CI], 6.2‒67.2, p < 0.001), having calcific synovitis (OR, 4.9; 95% CI, 2.4‒9.9, p < 0.001), womensex (OR, 3.3; 95% CI, 1.9‒5.7, p = 0.002), and not having atlantodens osteoarthritis (OR, 2.1; 95% CI, 1.2‒3.8, p = 0.014).Conclusion In the multivariable logistic regression analysis, age in the sixth decade or older, calcification of the transverseligament, being women, and not having atlantodens osteoarthritis were found to be significantly associated with atlantoaxialosteoarthritis. Delayed diagnosis and treatment can be avoided by focusing on these risk factors.
博士（医学）・甲第873号・令和5年3月15日
This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://doi.org/10.1007/s00586-022-07414-5
identifier:European spine journal Vol.31 No.12 p.3418-3425 (2022 Dec)
identifier:09406719
identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/4105
identifier:European spine journal, 31(12): 3418-3425
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